Longueuil, Canada Clinical Trials

A listing of Longueuil, Canada clinical trials actively recruiting patients volunteers.

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Found 1023 clinical trials
A Study of Oral Upadacitinib Tablets to Assess the Change in Disease Symptoms in Adult Canadian Participants With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study will assess how effective Upadacitinib is in changing the disease symptoms in Canadian participants with RA. Upadacitinib is a drug approved for the treatment of moderately to severely active …

Institut de Rhum. de Montreal /ID# 224045
 (2.5 away) Contact site
  • 07 Jul, 2021
  • +52 other locations
Host Response Mediators in Coronavirus (COVID-19) Infection

The coronavirus (COVID-19) pandemic continues to grow exponentially. Angiotensin II levels are increased in human influenza and are associated with influenza viral load, disease progression and mortality. Preliminary data shows angiotensin II receptor blockers (ARBs) limits lung injury in murine influenza H7N9, as well as viral titre and RNA. ARBs …

lung injury
ace inhibitor
coronavirus infection
Jewish General Hospital
 (3.6 away) Contact site
  • 24 Jan, 2021
  • +14 other locations
SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19)

Overall mortality of COVID-19 is variable and has been reported to be between less than 1% and 7%. Many authors around the world also reported data on hospitalization rate, need for intensive care unit (ICU) care and need for mechanical ventilation in SARS-CoV-2 infected patients. To provide anesthetic and surgical …

mechanical ventilation
Centre Hospitalier de l'Universit de Montr al (CHUM)
 (2.9 away) Contact site
  • 26 Sep, 2021
  • 1 location
Portal Pressure Effects of Phlebotomy Combined to Vasopressin Use in Cirrhotic Patients Undergoing Liver Transplantation

Liver transplantation is the standard treatment for chronic advanced liver disease, whether or not associated with a primary liver tumor. The intraoperative bleeding and the need for blood transfusion, encountered in this major surgery are associated with increased morbidity and mortality. However, this hemorrhagic risk has been drastically reduced in …

liver transplant
liver disease
intraoperative bleeding
blood transfusion
Centre Hospitalier de l'Universit de Montr al (CHUM)
 (2.9 away) Contact site
  • 23 Sep, 2021
  • 1 location
Understanding Decision Making in the Intensive Care Unit: a National Study

Given how central Substitute Decision Makers (SDMs) are to the process leading to end of life decisions and sometimes, organ donation, it is striking how poorly understood this decision-making process is. A 2017 scoping review on the topic of soliciting SDM consent to organ donation reported on more than 168 …

step 2
brain injury
Centre Hospitalier de l'Universit de Montr al (CHUM)
 (3.6 away) Contact site
  • 25 Jul, 2021
  • +8 other locations
Prevalence of Vertebral Fractures in Patients With Type 1 Diabetes

Background : Type 1 diabetes is associated with an increased risk of fractures. The mechanisms accounting for this bone fragility are not yet fully understood. The lower bone mineral density (BMD) observed in individuals with type 1 diabetes cannot solely explain the higher fracture incidence. Bone microarchitecture defects significantly contribute …

bone mineral density
dual-energy x-ray absorptiometry
Institut de recherches cliniques de Montr al (IRCM)
 (3.5 away) Contact site
  • 24 Jan, 2021
  • +1 other locations
Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface

This study aims to obtain the lacrimal fingerprint for frequent pathologies of the ocular surface and establish a normative base for each of them.

mucous membrane
dry eye syndrome
infectious keratitis
Centre Hospitalier de l'Universit de Montr al (CHUM)
 (2.9 away) Contact site
  • 13 Aug, 2021
  • +1 other locations
Brivaracetam: a Prospective and Multicentre Post-marketing Observational Study

Brivaracetam (BRV) is a new antiepileptic drug approved in March 2016 by Health Canada for the adjunctive treatment of focal epilepsy in adults. While randomized controlled trials represent the gold standard in measuring intervention efficacy, the generalizability of these findings to usual clinical practice remains uncertain. The primary objective of …

convulsive seizure
generalized epilepsy
generalized seizure
Centre Hospitalier de l'Universit de Montr al (CHUM)
 (3.6 away) Contact site
  • 26 Sep, 2021
  • 1 location
Viscoelasticity Imaging to Assess Liver Cancer

Ultrasound (US) used for hepatocellular carcinoma (HCC) surveillance suffers from low sensitivity (60-78%) due to fatty liver, obesity, and diffusely nodular appearance in cirrhosis. Once a suspicious malignant lesion is detected at US, guidelines recommend contrast-enhanced US, magnetic resonance imaging (MRI) or computed tomography (CT) scans to confirm suspicion. The …

Centre hospitalier de l'Universit de Montr al (CHUM)
 (3.6 away) Contact site
  • 29 Jan, 2021
  • 1 location
Mucopolysaccharidosis Type II Observational

This is an observational study planned to document prospectively disease manifestation and neurocognitive course in pediatric patients with a clinical presentation consistent with neuronopathic ("severe") MPS II undergoing current standard of care and/or intrathecal Elaprase for their condition. Some patients may be offered the opportunity to screen for a gene …

Mcgill University Health center
 (4.0 away) Contact site
  • 15 Aug, 2021
  • +3 other locations