Laval, Quebec, Canada Clinical Trials

A listing of Laval, Quebec, Canada clinical trials actively recruiting patients volunteers.

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Found 251 clinical trials
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COMMANDS - Myelodysplastic Syndromes (MDS) - ACE536-MDS-002 – Canada  

The study will be conducted in compliance with the International Council for Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good Clinical Practice (GCP) and applicable regulatory requirements.   This is an interventional active-controlled, open-label, randomized Phase 3 study to compare the efficacy and safety of luspatercept …

epoetin alfa
Hopital Maisonneuve Rosemont
 (7.7 away)
  • 33 views
  • 03 Aug, 2021
  • +9 other locations
A Study of Biomarker-Directed Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)

This study will investigate the utility of biomarker-based triage for study participants with advanced non-small cell lung cancer (NSCLC) without prior systemic therapy. Study participants within groups defined by a biomarker-based classifier (gene expression profile [GEP] and tumor mutational burden [TMB]) will be randomized to receive pembrolizumab in combination with …

Jewish General Hospital ( Site 0307)
 (8.5 away) Contact site
  • 352 views
  • 02 Aug, 2021
  • +92 other locations
Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC

Sometimes, cancer patients receive an initial treatment, followed by additional treatment to lower the chance of cancer coming back. The standard or usual treatment for this type of disease is initially having radiation therapy at the same time as chemotherapy (with a drug called cisplatin), with no additional therapy afterwards

treatment schedule
human papillomavirus
pet/ct scan
durvalumab
neutrophil count
The Jewish General Hospital
 (8.5 away) Contact site
  • 56 views
  • 24 Jul, 2021
  • +29 other locations
Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis

A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis

Research site
 (9.2 away) Contact site
  • 0 views
  • 24 Jul, 2021
  • +116 other locations
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

Research site
 (9.2 away) Contact site
  • 0 views
  • 02 Aug, 2021
  • +252 other locations
Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)

This study will assess the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of escalating doses of quavonlimab when used in combination with pembrolizumab in participants with advanced solid tumors.

Jewish General Hospital ( Site 1105)
 (8.5 away) Contact site
  • 748 views
  • 04 Aug, 2021
  • +52 other locations
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

Psoriasis (PsO) is a chronic disease characterized by marked inflammation of the skin that results in thick, red, scaly plaques. This study will assess how safe and effective risankizumab is compared to apremilast in adult participants with moderate plaque psoriasis. Adverse events and change in disease symptoms will be monitored. …

apremilast
risankizumab
systemic therapy
arthritis
plaque psoriasis
Innovaderm Research Inc. /ID# 230334
 (9.4 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +61 other locations
Safety Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (DME)

This study is intended to assess the safety, tolerability and evidence of pharmacodynamic activity of a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME)

Universite de Montreal
 (8.4 away) Contact site
  • 0 views
  • 26 Jul, 2021
  • +31 other locations
Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria

The purpose of this study is to determine the efficacy, durability and long-term safety of reloxaliase in patients with enteric hyperoxaluria.

Centre de recherche du Centre Hospitalier de l'Universite de Montreal
 (10.0 away) Contact site
  • 7 views
  • 04 Aug, 2021
  • +83 other locations
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to evaluate the efficacy and safety (including evaluating side effects) of combination of olaparib and abiraterone versus placebo and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemotherapy or new hormonal agents (NHAs) at metastatic castration-resistant prostate …

adenocarcinoma
androgen
abiraterone
progressive disease
gonadotropin releasing hormone
Research Site
 (9.9 away) Contact site
  • 200 views
  • 23 Jul, 2021
  • +194 other locations