Kitchener, Canada Clinical Trials

A listing of Kitchener, Canada clinical trials actively recruiting patients volunteers.

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Found 31 clinical trials
A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer

A phase III multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR+/HER2- Early Breast Cancer

Novartis Investigative Site
 (0.4 away) Contact site
  • 211 views
  • 17 Jul, 2021
  • +362 other locations
Efficacy and Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis

The main purpose of the study is to assess the efficacy and safety of nemolizumab after a 16-week treatment period in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD) not adequately controlled with topical treatments.

Galderma Investigational Site
 (1.5 away) Contact site
  • 95 views
  • 16 Jul, 2021
  • +458 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (1.5 away) Contact site
  • 21 views
  • 16 Jul, 2021
  • +470 other locations
A Study of Guselkumab in Participants With Active Psoriatic Arthritis

The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.

psoriatic plaque
polyarticular arthritis
arthritis mutilans
anti-rheumatic drugs
DMARD
K. Papp Clinical Research
 (1.5 away) Contact site
  • 0 views
  • 18 Jul, 2021
  • +209 other locations
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

Psoriasis (PsO) is a chronic disease characterized by marked inflammation of the skin that results in thick, red, scaly plaques. This study will assess how safe and effective risankizumab is compared to apremilast in adult participants with moderate plaque psoriasis. Adverse events and change in disease symptoms will be monitored. …

risankizumab
apremilast
systemic therapy
arthritis
plaque psoriasis
K. Papp Clinical Research /ID# 230336
 (1.5 away) Contact site
  • 0 views
  • 23 Jul, 2021
  • +61 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

ejection fraction
bypass graft
cardiac resynchronization therapy
b-type natriuretic peptide
iron
Vizel Cardiac Research
 (9.0 away) Contact site
  • 5316 views
  • 22 Jul, 2021
  • +365 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

body mass index
cardiovascular disease
overweight or obesity
Novo Nordisk Investigational Site
 (9.5 away) Contact site
  • 7712 views
  • 18 Jul, 2021
  • +1164 other locations
Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis

The purpose of this study is to evaluate the effect of TRC101 on the progression of chronic kidney disease (CKD) and to evaluate the safety profile of TRC101 in CKD patients with metabolic acidosis.

glomerular filtration rate
ace inhibitor
nephropathy
Investigative Site 4202
 (1.5 away) Contact site
  • 316 views
  • 20 Jul, 2021
  • +511 other locations
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming …

adjuvant chemotherapy
hormone therapy
sentinel lymph node biopsy
invasive carcinoma
core needle biopsy
Grand River Regional Cancer Centre at Grand River Hospital
 (0.4 away) Contact site
  • 591 views
  • 21 Jul, 2021
  • +318 other locations
Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal Pancreatic or Colorectal Cancer

Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects with Gastrointestinal, Pancreatic, or Colorectal Cancer

Research Site
 (0.4 away) Contact site
  • 143 views
  • 17 Jul, 2021
  • +185 other locations