Kelowna, Canada Clinical Trials

A listing of Kelowna, Canada clinical trials actively recruiting patients volunteers.

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Found 27 clinical trials
An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is a Phase 3, open-label, multicenter extension study to evaluate safety and efficacy of ozanimod in subjects with moderately to severely active Crohn's Disease.

crohn's disease
remission
Okanagan Clinical Trials Ltd
 (0.2 away) Contact site
  • 1032 views
  • 22 Feb, 2021
  • +807 other locations
A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a Phase 3, randomized, double-blind, placebo-controlled study to demonstrate the effect of oral ozanimod as maintenance therapy in subjects with moderately to severely active Crohn's Disease.

crohn's disease
abdominal pain
remission
Okanagan Clinical Trials Ltd
 (0.2 away) Contact site
  • 858 views
  • 23 Feb, 2021
  • +780 other locations
Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke

The proposed trial is a pragmatic, registry based, prospective, randomized (1:1) controlled, open-label parallel group clinical trial with blinded endpoint assessment of 1600 patients to test if intravenous tenecteplase (0.25 mg/kg body weight, max dose 25 mg) is non-inferior to intravenous alteplase (0.9 mg/kg body weight) in patients with acute …

ischemic stroke
acute stroke
plasminogen activator
thrombectomy
tissue plasminogen activator
Royal Columbian Hospital
 (159.6 away) Contact site
  • 31 views
  • 07 Mar, 2021
  • +23 other locations
Safety and Efficacy Study of Pembrolizumab (MK-3475) Combined With Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Advance Melanoma (MK-7902-003/E7080-G000-312/LEAP-003)

The purpose of this study is to assess the safety and efficacy of pembrolizumab (MK-3475) combined with lenvatinib (MK-7902/E7080) compared to pembrolizumab alone (with placebo for lenvatinib) as first-line treatment in adults with no prior systemic therapy for their advanced melanoma. The primary study hypotheses are that: 1) The combination …

cytotoxic t-lymphocyte antigen 4
metastatic melanoma
targeted therapy
measurable disease
braf v600 mutation
BC Cancer-Kelowna - Sindi Ahluwalia Hawkins Centre ( Site 0661)
 (1.0 away) Contact site
  • 150 views
  • 18 Jun, 2021
  • +125 other locations
Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment

A global study to assess the efficacy and safety of durvalumab in combination with bevacizumab or durvalumab alone in patients with hepatocellular carcinoma who are at high risk of recurrence.

durvalumab
bevacizumab
Research Site
 (1.0 away) Contact site
  • 75 views
  • 16 Jun, 2021
  • +242 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

flortaucipir
mini-mental state examination
positron emission tomography
florbetapir
alzheimer's disease
OCT Research ULC
 (0.2 away) Contact site
  • 79 views
  • 13 Jun, 2021
  • +382 other locations
A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this 12-month, open-label study is to see if the study drug lasmiditan is safe and effective for the intermittent acute treatment of migraine in children aged 6 to 17. The study will last about 12 months and may include up to 7 visits.

lasmiditan
acute treatment
migraine in children
ly573144
Okanagan Clinical Trials
 (0.2 away) Contact site
  • 129 views
  • 16 Jun, 2021
  • +236 other locations
PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

Currently, warfarin is the only approved anticoagulation for patients with mechanical valves. The purpose of this study is to determine if participants with an On-X Prosthetic Heart Valve / On-X aortic valve can be maintained safely and effectively on apixaban. Both the On-X aortic valve and apixaban have been approved …

aspirin
apixaban 5 mg
warfarin
Kelowna General Hospital
 (1.0 away) Contact site
  • 79 views
  • 17 Jun, 2021
  • +72 other locations
The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial

This is a Phase III multicentre randomized controlled trial (RCT) to evaluate the impact of tranexamic acid (TXA) on perioperative blood transfusion in patients undergoing liver resection. The rationale for this study includes: (1) experimental evidence supporting the use of TXA in other surgical populations; (2) lack of evidence in …

blood transfusion
primary cancer
cancer
liver surgery
Foothills Hospital
 (248.4 away) Contact site
  • 15 views
  • 26 Jan, 2021
  • +10 other locations
Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a Phase 3, randomized, double-blind, placebo-controlled study to explore the effect of oral ozanimod as an induction treatment for subjects with moderately to severely active Crohn's Disease.

endoscopy
corticosteroids
immunomodulators
crohn's disease
abdominal pain
Okanagan Clinical Trials Ltd
 (0.2 away) Contact site
  • 865 views
  • 09 Mar, 2021
  • +420 other locations