Halifax, Canada Clinical Trials

A listing of Halifax, Canada clinical trials actively recruiting patients volunteers.

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Found 270 clinical trials
The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial

This is a Phase III multicentre randomized controlled trial (RCT) to evaluate the impact of tranexamic acid (TXA) on perioperative blood transfusion in patients undergoing liver resection. The rationale for this study includes: (1) experimental evidence supporting the use of TXA in other surgical populations; (2) lack of evidence in …

primary cancer
cancer
blood transfusion
liver surgery
Queen Elizabeth II Health Sciences Centre
 (1.0 away) Contact site
  • 15 views
  • 26 Jan, 2021
  • +10 other locations
Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

This phase III trial studies how well response and biology-based risk factor-guided therapy works in treating younger patients with non-high risk neuroblastoma. Sometimes a tumor may not need treatment until it progresses. In this case, observation may be sufficient. Measuring biomarkers in tumor cells may help plan when effective treatment …

carboplatin
cancer
ganglioneuroblastoma
etoposide
tumor cells
IWK Health Centre
 (0.2 away) Contact site
  • 265 views
  • 02 Sep, 2021
  • +121 other locations
Myocardial Ischemia and Transfusion

The purpose of this study is to compare two red blood cell transfusion strategies (liberal and restrictive) for patients who have had an acute myocardial infarction and are anemic.

stemi
ischemia
myocardial infarction
red blood cell transfusion
acute myocardial infarction
Massachusetts General Hospital
 (380.4 away) Contact site
  • 385 views
  • 02 Sep, 2021
  • +136 other locations
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness

The World Health Organization, U.S. Centers for Disease Control and Prevention, Association of Medical Microbiology and Infectious Diseases (AMMI) Canada, and Health Canada have all declared antimicrobial resistance a global threat to health, based on rapidly increasing resistance rates and declining new drug development. Up to 30-50% of antibiotic use …

bloodstream infection
bacteremia
blood culture
antibiotics
antibiotic therapy
Centre hospitalier affili universitaire de Qu bec
 (395.6 away) Contact site
  • 4323 views
  • 27 Jan, 2021
  • +57 other locations
Induction Study #2 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a Phase 3, randomized, double-blind, placebo-controlled study to explore the effect of oral ozanimod as an induction treatment for subjects with moderately to severely active Crohn's Disease.

endoscopy
abdominal pain
immunomodulators
corticosteroids
ileal disease
IWK Health Center
 (1.4 away) Contact site
  • 412 views
  • 12 Mar, 2021
  • +387 other locations
A Study of ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation

This is a randomized, double-blind, placebo-controlled study in patients with dilated cardiomyopathy (DCM) due to a mutation of the gene encoding the lamin A/C protein (LMNA). The study will further evaluate a dose level of study drug (ARRY-371797) that has shown preliminary efficacy and safety in this patient population. After …

c protein
arry-371797
walk test
dilated cardiomyopathy
implantable cardioverter-defibrillators
Array BioPharma Investigative Site
 (0.6 away) Contact site
  • 420 views
  • 05 Sep, 2021
  • +261 other locations
A Study to Evaluate the Efficacy Safety and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants

The purpose of this study is to evaluate the efficacy and safety of guselkumab in pediatric participants aged greater than or equal to 6 through less than 18 years with chronic plaque psoriasis.

plaque psoriasis
varicella
arthritis
enbrel
etanercept
Eastern Canada Research Associates
 (0.9 away) Contact site
  • 51 views
  • 14 Aug, 2021
  • +49 other locations
Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A

The primary purpose of the study is to compare the efficacy and safety of canakinumab versus placebo as adjuvant therapy in adult subjects with stages AJCC/UICC v. 8 II -IIIA and the subset of IIIB (T>5cm N2 disease) completely resected (R0) non-small cell lung cancer (NSCLC).

alopecia
systemic therapy
lung carcinoma
Novartis Investigative Site
 (0.8 away) Contact site
  • 645 views
  • 19 Sep, 2021
  • +416 other locations
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

This randomized phase III trial studies how well combination chemotherapy (vincristine sulfate, dactinomycin, cyclophosphamide alternated with vincristine sulfate and irinotecan hydrochloride or vinorelbine) works compared to combination chemotherapy plus temsirolimus in treating patients with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle), and has an intermediate chance …

cancer
cancer chemotherapy
alveolar rhabdomyosarcoma
vincristine
actinomycin
IWK Health Centre
 (1.4 away) Contact site
  • 292 views
  • 19 Sep, 2021
  • +290 other locations
Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

This phase II trial studies how well reduced doses of radiation therapy to the brain and spine (craniospinal) and chemotherapy work in treating patients with newly diagnosed type of brain tumor called WNT)/Wingless (WNT)-driven medulloblastoma. Recent studies using chemotherapy and radiation therapy have been shown to be effective in treating …

cancer
immunohistochemistry
residual tumor
medulloblastoma
vincristine
IWK Health Centre
 (1.4 away) Contact site
  • 119 views
  • 03 Sep, 2021
  • +136 other locations