Halifax, Canada Clinical Trials

A listing of Halifax, Canada clinical trials actively recruiting patients volunteers.

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Found 74 clinical trials
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

heart disease
diuretic therapy
heart failure
natriuretic peptide
Queen Elizabeth II Health Sciences Centre
 (0.7 away) Contact site
  • 26 Sep, 2021
  • +784 other locations
A Research Study to Compare a New Weekly Insulin Insulin Icodec and an Available Daily Insulin Insulin Degludec Both in Combination With Mealtime Insulin in People With Type 1 Diabetes (ONWARDS 6)

This study compares insulin icodec (a new insulin) to insulin degludec (an insulin already available on the market) in people with type 1 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin degludec taken daily. Participants will either get insulin icodec …

Novo Nordisk Investigational Site
 (0.7 away) Contact site
  • 26 Sep, 2021
  • +87 other locations
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease. Participants will either get semaglutide or placebo (a "dummy" medicine which does not contain any study medicine) - which treatment participants get is decided by an equal chance. The study will …

Novo Nordisk Investigational Site
 (0.7 away) Contact site
  • 26 Sep, 2021
  • +161 other locations
A Study of LY3471851 in Adult Participants With Moderately to Severely Active Ulcerative Colitis (UC)

The reason for this study is to determine if the study drug LY3471851 is safe and effective in adult participants with active ulcerative colitis (UC). The study will last about 52 weeks.

tumor necrosis factor
Gastroenterology Research, Nova Scotia Health Authority
 (0.8 away) Contact site
  • 26 Sep, 2021
  • +140 other locations
Study of LOXO-305 Versus Investigator's Choice (IdelaR or BR) in Patients With CLL or SLL

This is a study for patients with chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL) who have previously received treatment with at least a BTK inhibitor. The main purpose is to compare LOXO-305 to idelalisib plus rituximab or bendamustine plus rituximab. Participation could last up to four years, and …

chronic lymphocytic leukemia
neutrophil count
Queen Elizabeth II Health Sciences Center
 (0.6 away) Contact site
  • 26 Sep, 2021
  • +110 other locations
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness

The World Health Organization, U.S. Centers for Disease Control and Prevention, Association of Medical Microbiology and Infectious Diseases (AMMI) Canada, and Health Canada have all declared antimicrobial resistance a global threat to health, based on rapidly increasing resistance rates and declining new drug development. Up to 30-50% of antibiotic use …

antimicrobial agent
antibiotic therapy
Centre hospitalier affili universitaire de Qu bec
 (395.6 away) Contact site
  • 27 Sep, 2021
  • +58 other locations
Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)

This study will evaluate the safety and efficacy of pembrolizumab (MK-3475) versus placebo as adjuvant therapy in participants with hepatocellular carcinoma (HCC) and complete radiological response after surgical resection or local ablation. The primary hypotheses of this study are that adjuvant pembrolizumab is superior to placebo with respect to: 1) …

ct scan
alpha fetoprotein
Nova Scotia Health Authority QEII-HSC ( Site 0208)
 (0.7 away) Contact site
  • 27 Sep, 2021
  • +257 other locations
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases

Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain. Whole brain radiation therapy with hippocampal …

stereotactic radiosurgery
brain tumor
whole-brain radiotherapy
QEII Health Sciences Centre/Nova Scotia Health Authority
 (0.7 away) Contact site
  • 20 Sep, 2021
  • +71 other locations
Neuro RX Gamma - Pivotal Phase

The active Neuro RX Gamma device uses non-invasive near-infrared energy delivered to the brain with the intention to improve cognitive functioning and quality of life in patients with moderate to severe Alzheimer's Disease. Treatment will occur at home-based treatment sessions with the device.

speech therapy
alzheimer's disease
mini-mental state examination
mental state examination
True North Clinical Research
 (4.7 away) Contact site
  • 20 Sep, 2021
  • +10 other locations
Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma

The purpose of this study is to find out what effects new combinations of treatment will have this disease. New promising treatment strategies will be added to this study as they are available to be compared against the standard treatment.

b-cell lymphoma
chop regimen
measurable disease
granulocyte colony stimulating factor
QEII Health Sciences Centre
 (0.8 away) Contact site
  • 20 Sep, 2021
  • +15 other locations