Halifax, Nova Scotia, Canada Clinical Trials

A listing of Halifax, Nova Scotia, Canada clinical trials actively recruiting patients volunteers.

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Found 277 clinical trials
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C3711005  

The study will evaluate the effect of coadministration of a range of doses of DGAT2i with 1 dose of ACCi, on hepatic steatosis and the ability of DGAT2i to mitigate ACCi-induced elevations in serum triglycerides. The study has a 2-part design with sequential conduct of Part 1 and Part 2 …

Nova Scotia Health Authority QE II Health Sciences Centre
 (0.7 away)
  • 0 views
  • 08 Jul, 2021
  • +9 other locations
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require …

Queen Elizabeth II Health Science Centre
 (0.8 away) Contact site
  • 41 views
  • 26 Jan, 2021
  • +97 other locations
A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

cyclin d1
acalabrutinib
rituximab
bendamustine
Research Site
 (0.7 away) Contact site
  • 1270 views
  • 24 Jul, 2021
  • +250 other locations
A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer

A phase III multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant treatment in patients with HR+/HER2- Early Breast Cancer

Novartis Investigative Site
 (0.8 away) Contact site
  • 211 views
  • 17 Jul, 2021
  • +362 other locations
Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to evaluate the efficacy and safety (including evaluating side effects) of combination of olaparib and abiraterone versus placebo and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemotherapy or new hormonal agents (NHAs) at metastatic castration-resistant prostate …

serum testosterone
olaparib
prostate adenocarcinoma
gonadotropin releasing hormone
androgen
Research Site
 (0.8 away) Contact site
  • 200 views
  • 23 Jul, 2021
  • +194 other locations
Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients

This trial investigates the efficacy and safety of clazakizumab [an anti-interleukin (IL)-6 monoclonal antibody (mAb)] for the treatment of CABMR in recipients of a kidney transplant.

Queen Elizabeth II Health Sciences Centre
 (0.8 away) Contact site
  • 1 views
  • 01 Mar, 2021
  • +55 other locations
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus

The study is a 2-arm, double blinded, multicenter, 2:1 randomized, placebo controlled clinical trial. Subjects will receive hydroxychloroquine or placebo and close monitoring for progression of T1D.

IWK Health Center
 (1.4 away) Contact site
  • 190 views
  • 24 Jan, 2021
  • +45 other locations
A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determining the superiority of lecanemab compared with placebo on the change from baseline in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) at 18 months of treatment in the Core Study. This …

True North Clinical Research Halifax, Inc.
 (4.7 away) Contact site
  • 242 views
  • 05 Jul, 2021
  • +275 other locations
A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer Compared to Nab-paclitaxel+Gemcitabine Treatment

The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5 fluorouracil/leucovorin (5FU/LV) plus oxaliplatin compared to nab-paclitaxel + gemcitabine treatment in improving the overall survival of patients not previously treated for …

Queen Elizabeth II Health Sciences Centre
 (0.6 away) Contact site
  • 31 views
  • 03 Jul, 2021
  • +273 other locations
Study to Assess Effectiveness of GlaxoSmithKline's (GSK's) Meningococcal Group B and Combined ABCWY Vaccines in Healthy Adolescents and Young Adults.

The purpose of this study is to evaluate the effectiveness of 2 doses or 3 doses of GSK's licenced meningococcal group B Bexsero (rMenB+OMV NZ) vaccine and of 2 doses of GSK's investigational combined meningococcal (MenABCWY) vaccine (GSK3536819A) in healthy adolescents and young adults. The immunogenicity and safety will also …

conjugate vaccine
menacwy
vaccination
bexsero
GSK Investigational Site
 (1.4 away) Contact site
  • 0 views
  • 01 May, 2021
  • +100 other locations