Georgetown, Canada Clinical Trials

A listing of Georgetown, Canada clinical trials actively recruiting patients volunteers.

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Found 16 clinical trials
The Impact of a Fast Diet and Calorie Mimetic Supplements on Epigenetic Aging

This is a prospective randomized clinical study of 50 patients to evaluate the fasting mimicking diet program by Prolon with a calorie mimetic supplement from Peak Human Labs. This study will be evaluating the effectiveness of the combined intervention over a three month program. The study will assess the effects …

Peak Human Labs
 (8.3 away) Contact site
  • 24 Jul, 2021
  • 1 location
Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy

This is an open-label, multi-centre, umbrella Phase II study in patients with metastatic NSCLC who have progressed on an anti-PD-1/PD-L1 containing therapy. This study is modular in design, allowing initial assessment of the efficacy, safety, and tolerability of multiple treatment arms.

recurrent non-small cell lung cancer
stage iv non-small cell lung cancer
Research Site
 (9.9 away) Contact site
  • 14 May, 2021
  • +54 other locations
Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy

Cancer cachexia is a multi-factorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment. There is an urgency for improving management, but there is no consensus on …

targeted therapy
cancer treatment
advanced cancer
CA4 Brampton Civic Hospital
 (9.0 away) Contact site
  • 14 Mar, 2021
  • +18 other locations
Study to Evaluate the Efficacy Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH)

This study will assess the efficacy of vibegron compared with placebo in men with overactive bladder (OAB) symptoms on pharmacological therapy for benign prostatic hyperplasia (BPH) as defined by micturition and urgency episodes.

micturition chart
benign prostatic hypertrophy
alpha blocker
Practice Dr Jonathan Giddens
 (9.0 away) Contact site
  • 15 Jul, 2021
  • +170 other locations
A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis

A double-blind placebo controlled randomized Phase 3 study to determine if 80 or 100 mg of MGL-3196 as compared with placebo resolves NASH on liver biopsy and prevents progression to cirrhosis and/or advanced liver disease

liver disease
hepatic fibrosis
LMC/ Manna Research - Brampton
 (9.0 away) Contact site
  • 17 Jul, 2021
  • +229 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

arterial disease
myocardial infarction
Brampton Clinical Trials
 (7.7 away) Contact site
  • 04 Jul, 2021
  • +1332 other locations
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

ejection fraction
heart failure
heart disease
b-type natriuretic peptide
Brampton Clinical Trials
 (7.7 away) Contact site
  • 03 Jul, 2021
  • +774 other locations
Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults

This Phase 2/3 study is a multi-portion design to confirm that the chosen formulation and dosing regimen of CoVLP has an acceptable immunogenicity and safety profile. The Phase 3 portion is an event-driven, randomized, observer blinded, placebo-controlled design that will evaluate the efficacy and safety of the CoVLP formulation compared …

Aggarwal and associates Ltd
 (9.0 away) Contact site
  • 25 Jul, 2021
  • +73 other locations
DOuble SEquential External Defibrillation for Refractory VF

Despite significant advances in resuscitation efforts, there are some patients who remain in refractory ventricular fibrillation (VF) during out-of-hospital cardiac arrest. Double sequential external defibrillation (DSED) and vector change defibrillation have been proposed as viable options for patients in refractory VF. This cluster randomized trial will compare (1) continued resuscitation …

Peel Regional Paramedic Service
 (9.0 away) Contact site
  • 25 Jul, 2021
  • +3 other locations
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness

The World Health Organization, U.S. Centers for Disease Control and Prevention, Association of Medical Microbiology and Infectious Diseases (AMMI) Canada, and Health Canada have all declared antimicrobial resistance a global threat to health, based on rapidly increasing resistance rates and declining new drug development. Up to 30-50% of antibiotic use …

antimicrobial agent
critical illness
antibiotic therapy
blood culture
William Osler Health System
 (9.0 away) Contact site
  • 27 Jan, 2021
  • +57 other locations