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Etobicoke,, Canada Clinical Trials

A listing of Etobicoke,, Canada clinical trials actively recruiting patients volunteers.

RESULTS

Found (245) clinical trials

Neurocognitive Functioning in Patients With Hepatitis C Pre- and Post-Treatment With Antiviral Medication

The current proposal addresses the hypothesis that neurocognitive and neurochemical abnormalities may occur in individuals with HCV-infection who do not have liver cirrhosis or vasculitic neuropathy, and that this phenomenon may result from a direct effect of HCV on the Central Nervous System (CNS). Our hypothesis originated from the frequently ...

Phase N/A

5.85 miles

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Family Studies in Primary Biliary Cirrhosis (PBC)

This proposal is predicated on cumulative data revealing a major role for genetic factors in PBC and the recent positional cloning of genes for Crohn’s disease, type 2 diabetes and rheumatoid as well as psoriatic arthritis data provide the “proof-of-principle” that susceptibility genes for multigenic diseases can be identified by ...

Phase N/A

5.85 miles

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Assessment of SpondyloArthritis Society (ASAS) Classification and Diagnostic Criteria for Early Axial Spondyloarthritis (SpA)

Background: Existing criteria for AS/SpA such as mod. New York, ESSG, or Amor criteria for classification and/or diagnosis of spondyloarthritis have limitations when applied to early disease. Moreover, MRI is not part of any of the established criteria and the precise role of MRI in early axial disease has not ...

Phase N/A

5.85 miles

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Diagnosing Frontotemporal Lobar Degeneration

The goal of this study is to determine the best diagnostic test for diagnosing frontotemporal lobar degeneration. To accomplish this, the current study will evaluate different tests: brain imaging, skin biopsy, body fluid samples (blood and cerebrospinal fluid), thinking abilities, everyday functioning, and brain autopsy. The study team hopes that ...

Phase N/A

5.85 miles

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Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)

Frontotemporal Lobar Degeneration (FTLD) is the neuropathological term for a collection of rare neurodegenerative diseases that correspond to four main overlapping clinical syndromes: frontotemporal dementia (FTD), primary progressive aphasia (PPA), corticobasal degeneration syndrome (CBS) and progressive supranuclear palsy syndrome (PSPS). The goal of this study is to build a FTLD ...

Phase N/A

5.85 miles

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BEAM: Brain-Eye Amyloid Memory Study

Retinal correlations with neurodegeneration: Retinal nerve fiber layer (RNFL) pattern will differ in participants in the MCI and early stages of LBD spectrum, AD, and VCI, relative to normal elders. i) RNFL thinning around the optic disc and macular thinning will correlate with hippocampal atrophy and with the cortical thickness ...

Phase N/A

5.85 miles

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Primary Tumor Research and Outcome Network

Objective: To prospectively investigate the prognostic variables (clinical, diagnostic, and therapeutic) within subgroups of patients diagnosed with primary spinal column tumors that are associated with: survival local recurrence perioperative morbidity patient reported outcomes Outcome measures: Variables applicable to primary spinal column tumor patients which will be collected in the registry ...

Phase N/A

5.85 miles

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A Protocol of the Canadian Prospective Study for Hepatocellular Carcinoma Surveillance Using Biomarkers

This study is a prospective randomized controlled trial (RCT) comparing surveillance for hepatocellular carcinoma with ultrasound alone versus ultrasound and standard biomarkers. The study will be conducted initially at UHN (TGH and TWH). One arm will undergo surveillance for hepatocellular carcinoma using ultrasound (US) alone and the other will undergo ...

Phase N/A

5.85 miles

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Observational Study Evaluating Long-term Health Outcomes of Canadian DUODOPA-treated Patients

This is an open-label, postmarketing, observational study to document health outcomes, in Canadian patients with advanced Parkinson's disease and long-term treatment with Duodopa (levodopa/carbidopa intestinal gel).

Phase N/A

5.85 miles

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Identification of the Genetic Variants Responsible for Primary Biliary Cirrhosis (PBC)

Very recently, a single nucleotide polymorphism (SNP) in the PTPN22 gene encoding the Lyp (lymphoid-specific phosphatase) PTP has been shown to be associated with susceptibility to rheumatoid arthritis (RA) and Type 1 diabetes (T1D)4,5. These data are consistent with the known role for Lyp in suppressing T cell activation and ...

Phase N/A

5.85 miles

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