Chicoutimi, Canada Clinical Trials

A listing of Chicoutimi, Canada clinical trials actively recruiting patients volunteers.

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Found 74 clinical trials
A Phase 3, Randomized, Comparator-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-risk Non-muscle Invasive Bladder Cancer (HR NMIBC) That is Either Persistent or Recurrent Following BCG Induction or That is Naïve to BCG Treatment (KEYNOTE-676)

This study is designed to assess the antitumor efficacy and safety of pembrolizumab in combination with BCG, compared to BCG monotherapy, in participants with HR NMIBC that is either persistent or recurrent following adequate BCG induction (Cohort A), or that is naïve to BCG treatment (Cohort B). The primary hypothesis …

CIUSSS du Saguenay-Lac-St-Jean ( Site 0164)
 (6.5 away) Contact site
  • 129 views
  • 22 Oct, 2022
  • +143 other locations
A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seamless Phase 2b/3, Parallel-group Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (INTREPID Lead-In) (INTREPID)

This study seeks to evaluate the safety and efficacy of brazikumab versus placebo (Stage I) and versus an active comparator (Stage 2) in participants with moderately to severely active CD and will include assessments of clinical response as demonstrated by improvement of symptoms and colonic mucosal appearance as observed on …

antibiotics
mercaptopurine
prednisone
azathioprine
aminosalicylate
Research Site
 (6.6 away) Contact site
  • 550 views
  • 20 Oct, 2022
  • +77 other locations
Study of ARO-APOC3 in Adults With Familial Chylomicronemia Syndrome (FCS) (PALISADE)

The purpose or AROAPOC3-3001 is to evaluate the efficacy and safety of ARO-APOC3 in adult participants with familial chylomicronemia syndrome (FCS). Participants who have met all protocol eligibility criteria will be randomized to receive 4 total doses of ARO-APOC3 or matching placebo administered subcutaneously.

Research Site
 (6.6 away) Contact site
  • 0 views
  • 07 Oct, 2022
  • +24 other locations
A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Zilebesiran Used as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)

The purpose of this study is to evaluate the effect of zilebesiran on systolic and diastolic blood pressure and to characterize the pharmacodynamic (PD) effects and safety of zilebesiran as add-on therapy.

hypertension
amlodipine
olmesartan
antihypertensive drugs
Clinical Trial Site
 (6.6 away) Contact site
  • 8 views
  • 13 Oct, 2022
  • +92 other locations
A Randomized, Double-blind, Placebo-Controlled, Dose-Ranging Multicenter Study to Evaluate the Efficacy and Safety of ALN-AGT01 in Patients With Mild-to-Moderate Hypertension (KARDIA-1)

The purpose of this study is to evaluate the effect of ALN-AGT01 on systolic and diastolic blood pressure and to characterize the pharmacodynamic (PD) effects and safety of ALN-AGT01.

hypertension
antihypertensive drugs
systolic blood pressure
Clinical Trial Site
 (6.6 away) Contact site
  • 44 views
  • 25 Oct, 2022
  • +83 other locations
A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Therapy After Surgery With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle Invasive Bladder Cancer

The purpose of this study is to compare nivolumab plus neoadjuvant gemcitabine/cisplatin (GC) chemotherapy, followed by post-surgery continuation of immuno-oncology (IO) therapy, with neoadjuvant GC chemotherapy alone in adult participants with previously untreated muscle-invasive bladder cancer (MIBC).

invasive bladder cancer
bladder cancer
nivolumab
radical cystectomy
gemcitabine
Local Institution - 0192
 (6.5 away) Contact site
  • 98 views
  • 09 Jul, 2022
  • +163 other locations
Phase III Radium 223 mCRPC-PEACE III (PEACE III)

The primary objective of the trial is to assess if upfront combination of enzalutamide and Ra223 improves radiological progression-free survival (rPFS1) compared to enzalutamide single agent in CRPC patients metastatic to bone

docetaxel
luteinizing hormone
diphosphonates
antiandrogen therapy
prednisone
Centre De Sante Et De Services Sociaux De Chicoutimi
 (6.5 away) Contact site
  • 514 views
  • 03 Jul, 2022
  • +61 other locations
TALAPRO-3: A PHASE 3, RANDOMIZED, DOUBLE-BLIND, STUDY OF TALAZOPARIB WITH ENZALUTAMIDE VERSUS PLACEBO WITH ENZALUTAMIDE IN MEN WITH DDR GENE MUTATED METASTATIC CASTRATION-SENSITIVE PROSTATE CANCER

The purpose of the study is to evaluate the safety and efficacy of talazoparib in combination with enzalutamide compared with placebo in combination with enzalutamide in participants with DDR-deficient mCSPC.

CIUSSS- saguenay-Lac-Saint-Jean
 (6.5 away) Contact site
  • 0 views
  • 25 Oct, 2022
  • +210 other locations
My Choices: Efficacy and Implementation Study

The aim of the study is to assess the efficacy of the My Choices - Alcohol program by comparing alcohol-use of people before and after doing the program to people that did not do the program on the same period of time (3 months).

Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay-Lac-Saint-Jean
 (6.1 away) Contact site
  • 0 views
  • 15 Jul, 2022
  • +3 other locations
Effects of a 12-week Strength Training Program in Women With Myotonic Dystrophy Type 1

20 women with myotonic dystrophy type 1 (DM1) will complete a 12-week lower-limb strength training program. The training program consist of 3 series of 6 to 8 maximal repetitions of 5 different exercises: Leg extension, leg press, hip abduction, squat and plantar flexion. Training sessions will be closely supervise and …

myotonic dystrophy
Groupe de recherche interdisciplinaire sur les maladies neuromusculaires
 (6.3 away) Contact site
  • 0 views
  • 20 Jun, 2022
  • 1 location