Chicoutimi, Canada Clinical Trials

A listing of Chicoutimi, Canada clinical trials actively recruiting patients volunteers.

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Found 76 clinical trials
Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)

The effect of sacubitril/valsartan vs. valsartan on changes in NT-proBNP, safety, and tolerability in HFpEF patients with a WHF event (HFpEF decompensation) who have been stabilized and initiated at the time of or within 30 days post-decompensation.

Novartis Investigative Site
 (6.5 away) Contact site
  • 44 views
  • 21 Jul, 2022
  • +121 other locations
A Remote Physical Activity Program in the Population Suffering From Type 1 Myotonic Dystrophy

The COVID-19 pandemic exacerbates health problems by reducing access to adapted and advanced physical rehabilitation for several people who need rehabilitation services, including the population with myotonic dystrophy type 1 (DM1). The PACE tool, an innovative web tool integrating pragmatic physical activity programs, seems to be an interesting and innovative …

Groupe de recherche interdisciplinaire Groupe de recherche interdisciplinaire sur les maladies neuromusculaires
 (6.0 away) Contact site
  • 0 views
  • 15 Oct, 2021
  • +1 other locations
Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH) (Gateway)

Participants with documented homozygous familial hypercholesterolemia (HoFH) who have provided informed consent will receive 2 open-label doses of ARO-ANG3 and be evaluated for safety and efficacy parameters through 36 weeks.

Clinique des Maladies Lipidiques de Quebec Inc
 (108.9 away) Contact site
  • 0 views
  • 28 Jul, 2022
  • +5 other locations
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

The purpose of the study is to evaluate the safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) effects of olezarsen (formerly known as AKCEA -APOCIII-LRX) in participants with FCS previously treated with volanesorsen.

Clinique des Maladies Lipidiques de Quebec Inc.
 (108.9 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • +8 other locations
EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF) (ENRICH-AF)

To assess whether edoxaban (60/30 mg daily) compared to non-antithrombotic medical therapy (either no antithrombotic therapy or antiplatelet monotherapy) reduces the risk of stroke (composite of ischemic, hemorrhagic and unspecified stroke) in high-risk atrial fibrillation (CHA2DS2-VASc 2) patients with previous intracranial hemorrhage.

stroke
atrial fibrillation
fibrillation
anticoagulants
vascular disease
Centre integre universitaire de sante et de services sociaux du Saguenay-Lac-Saint-Jean
 (6.5 away) Contact site
  • 15 views
  • 16 Feb, 2022
  • +139 other locations
A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial Disease and Type 2 Diabetes (STRIDE)

This study is done to see if semaglutide has an effect on walking ability compared with placebo (dummy medicine) in people with peripheral arterial disease (PAD) and type 2 diabetes. Participants will either get semaglutide or placebo ("dummy") medicine - which treatment participants get is decided by chance. Semaglutide is …

intermittent claudication
diabetes
pain-free
Novo Nordisk Investigational Site
 (6.6 away) Contact site
  • 118 views
  • 24 Apr, 2022
  • +91 other locations
Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2) (KARDIA-2)

The purpose of this study is to evaluate the effect of zilebesiran on systolic and diastolic blood pressure and to characterize the pharmacodynamic (PD) effects and safety of zilebesiran as add-on therapy.

olmesartan
amlodipine
hypertension
antihypertensive drugs
Clinical Trial Site
 (6.6 away) Contact site
  • 0 views
  • 23 Jul, 2022
  • +84 other locations
A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seamless Phase 2b/3, Parallel-group Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (INTREPID Lead-In) (INTREPID)

This study seeks to evaluate the safety and efficacy of brazikumab versus placebo (Stage I) and versus an active comparator (Stage 2) in participants with moderately to severely active CD and will include assessments of clinical response as demonstrated by improvement of symptoms and colonic mucosal appearance as observed on …

methotrexate
crohn's disease
mercaptopurine
antibiotics
immunomodulators
Research Site
 (6.6 away) Contact site
  • 550 views
  • 14 Sep, 2022
  • +76 other locations
A Phase 3, Randomized, Comparator-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-risk Non-muscle Invasive Bladder Cancer (HR NMIBC) That is Either Persistent or Recurrent Following BCG Induction or That is Naïve to BCG Treatment (KEYNOTE-676)

This study is designed to assess the antitumor efficacy and safety of pembrolizumab in combination with BCG, compared to BCG monotherapy, in participants with HR NMIBC that is either persistent or recurrent following adequate BCG induction (Cohort A), or that is naïve to BCG treatment (Cohort B). The primary hypothesis …

CIUSSS du Saguenay-Lac-St-Jean ( Site 0164)
 (6.5 away) Contact site
  • 116 views
  • 17 Sep, 2022
  • +138 other locations
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of LY3561774 in Adults With Mixed Dyslipidemia (PROLONG-ANG3)

This a multicenter, Phase 2b, double-blind, placebo-controlled, parallel group study to provide data on efficacy and safety of LY3561774 administered subcutaneously at various doses in participants with mixed dyslipidemia and on a stable dose of a statin.

fasting
hmg-coa reductase inhibitors
body mass index
Clinique des maladies lipidiques de Quebec
 (108.9 away) Contact site
  • 0 views
  • 14 Sep, 2022
  • +33 other locations