Cambridge, Canada Clinical Trials

A listing of Cambridge, Canada clinical trials actively recruiting patients volunteers.

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Found 16 clinical trials
Efficacy and Safety of Etripamil for the Termination of Spontaneous PSVT. NODE 301 [Part 1 and Part 2 (The RAPID Study)]

This is a two-part, multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of etripamil NS self-administered by patients who experience an episode of paroxysmal ventricular tachycardia (PSVT) in an at-home setting. Part 1 comprised the conduct of the NODE-301 study up to the date of the adjudication …

Cambridge Cardiac Care Centre
 (1.3 away) Contact site
  • 281 views
  • 05 May, 2021
  • +127 other locations
Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303

NODE-303 is a multi-center, open label (OL) study to evaluate the safety of etripamil NS in patients with Paroxysmal Supraventricular Tachycardia (PSVT). Patients will be provided with an ambulatory Cardiac Monitoring System (CMS) to help document PSVT episodes. The CMS will be self-applied by the patient, when PSVT symptoms begin. …

0215
 (1.3 away) Contact site
  • 109 views
  • 27 Jan, 2021
  • +146 other locations
Peer Administered Online CBT for PPD

Postpartum depression (PPD) affects up to one in five of women and has profound effects on mothers and their infants. Unfortunately, fewer than 15% of women with PPD receive evidence-based care. This is at least partly due to significant difficulties faced by women in accessing psychotherapies, their preferred treatment for …

behavior therapy
depressed mood
Kids Can Fly
 (9.9 away) Contact site
  • 0 views
  • 03 Jul, 2021
  • 1 location
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

nt-probnp
iron
bypass graft
natriuretic peptide
ejection fraction
Cambridge Cardiac Care Center
 (1.3 away) Contact site
  • 5316 views
  • 02 Aug, 2021
  • +365 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

body mass index
cardiovascular disease
overweight or obesity
Novo Nordisk Investigational Site
 (1.3 away) Contact site
  • 7727 views
  • 18 Jul, 2021
  • +1164 other locations
Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer

Primary Objective: To determine whether amcenestrant per os improves progression free survival (PFS) when compared with a endocrine monotherapy of the choice of the physician, in participants with metastatic or locally advanced breast cancer Secondary Objectives: To compare the overall survival in the 2 treatment arms To assess the objective …

exemestane
hormone therapy
ESR1
breast cancer
adenocarcinoma
Investigational Site Number 1240002
 (1.3 away) Contact site
  • 213 views
  • 13 Jun, 2021
  • +168 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

hemoglobin a1c
body mass index
cardiovascular disease
Cambridge Cardiac Care Centre
 (1.3 away) Contact site
  • 593 views
  • 29 Jul, 2021
  • +888 other locations
Hockey Fans in Training (Hockey FIT): Improving Men's Health Through the Power of Sport

Hockey Fans in Training (Hockey FIT) is a 12-month (3-month active phase and 9-month minimally-supported phase) weight loss and healthy lifestyle program for middle-aged, overweight/obese male hockey fans, delivered by trained coaches in collaboration with major junior or professional hockey teams and implementation partners (e.g., YMCAs, local fitness facilities, and …

A.R. Kaufman Family YMCA
 (9.2 away) Contact site
  • 0 views
  • 26 Jan, 2021
  • +31 other locations
EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)

This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to go to the hospital for heart failure and whether it lowers the chances of dying …

atherosclerosis
st elevation myocardial infarction
angiography
cardiovascular disease
revascularisation
Cambridge Cardiac Care Inc.
 (1.3 away) Contact site
  • 0 views
  • 04 Aug, 2021
  • +188 other locations
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

nt-probnp
diuretic therapy
ejection fraction
heart disease
stroke
Cambridge Cardiac Care Center
 (1.3 away) Contact site
  • 0 views
  • 01 Aug, 2021
  • +778 other locations