Burlington, Canada Clinical Trials

A listing of Burlington, Canada clinical trials actively recruiting patients volunteers.

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Found 197 clinical trials
A Double-Blind Placebo-Controlled Randomized Phase III Trial of Fulvestrant and Ipatasertib as Treatment for Advanced HER-2 Negative and Estrogen Receptor Positive (ER+) Breast Cancer Following Progression on First Line CDK 4/6 Inhibitor and Aromatase Inhibitor (FINER)

The purpose of this study is to find out whether a new drug, Ipatasertib, can slow the growth of advanced breast cancer when added to standard therapy (Fulvestrant).

metastasis
fulvestrant
erbb2
advanced breast cancer
aromatase inhibitor
Juravinski Cancer Centre at Hamilton Health Sciences
 (6.3 away) Contact site
  • 39 views
  • 23 Oct, 2022
  • +37 other locations
The Family Check-Up: Implementing a New Family-Centred Model Within Autism Services

Many children and youth with autism spectrum disorder have high levels of emotional and behavioural problems. Parents play a powerful role in supporting their children's well-being. Research also shows that certain factors (e.g., parent mental health, access to services) can affect autistic children's well-being in important ways. Despite this, autism …

McMaster University
 (6.6 away) Contact site
  • 0 views
  • 23 Oct, 2022
  • 1 location
Low INR to Minimize Bleeding With Mechanical Valves Trial (LIMIT)

This study evaluates the use of a lower INR target (1.5 to 2.5) in patients with a mechanical heart valve in the aortic position. This study will inform physicians about whether a lower INR target will decrease the risk of bleeding or increase the risk of blood clot formation and …

Hamilton General Hospital
 (5.2 away) Contact site
  • 0 views
  • 23 Oct, 2022
  • +3 other locations
Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome Phase IV Pilot Study (TILE)

The TILE pilot study will be a multicenter, open-label, assessor-blinded RCT (randomized control trial) comparing extended LMWH (Low Molecular Weight Heparin) vs. DOAC (Direct Oral Anticoagulants) to PTS (prevent post thrombotic syndrome) in patients with DVT (Deep Vein Thrombosis).

tinzaparin
blood clot
anticoagulants
dvts
clot
Hamilton General Hospital
 (5.2 away) Contact site
  • 0 views
  • 12 Oct, 2022
  • +3 other locations
Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation (Ketodex)

Orthopedic injuries comprise more than 10% of ED visits in children and 25 to 50% of children will sustain a fracture before age 16 years. Distal radius fractures account for 20-32% of fractures in children, making them the most common fracture type. Between 20 and 40% of extremity fractures in …

dislocation
sedatives
ketamine
injuries
ulna fracture
McMaster Children's Hospital
 (6.0 away) Contact site
  • 144 views
  • 04 Oct, 2022
  • +3 other locations
A Community-based Program That Supports Physical Activity, Healthy Eating, Social Participation and System Navigation in Older Adults (EMBOLDEN)

Physical mobility and social participation are needed to maintain independence and quality of life for adults over 55 years of age. Despite the known benefits of physical activity and dietary change programs for older adults, the best ways to deliver these interventions are not well understood. The goal of the …

Accepts healthy volunteers
Community
 (6.0 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location
Evaluation of Emerging New Treatments for Infection Prevention in Total Joint Replacement (PREVENT-IT)

At the end of total joint replacement (TJR) surgery, surgeons wash and clean the surgical wound. This is done to lower the risk of infections. Currently, most surgeons use saline to wash the surgical wound and do not place antibiotics in the wound . However, some recent studies have shown …

Hamilton Health Sciences- Juravinkski Hospital
 (6.3 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Non-pharmacological Cough Control Therapy

Coughing affects almost all individuals with ILD leading to physical, psychological and social distress and prevents individuals from performing their activities of daily living, working or socialising in public places. Unfortunately, there are no licensed medications available to treat chronic cough and the few drugs that have been tried resulted …

interstitial lung disease
pulmonary rehabilitation
St. Joseph's Healthcare Hamilton
 (7.5 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • +1 other locations
EPI-7386 in Combination With Enzalutamide Compared With Enzalutamide Alone in Subjects With mCRPC

This is a Phase 1/2 study of EPI-7386 orally administered in combination with enzalutamide in subjects with mCRPC. Phase 1 of the study will be a single-arm dose escalation study of EPI-7386 in combination with a fixed dose of enzalutamide. This portion of the study will primarily evaluate the safety …

Juravinski Cancer Centre, Hamilton, ON L8V 5C2
 (6.3 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • +6 other locations
Transition to LIVE (Long-term In Home Ventilation Engagement) Study

The rising prevalence of ventilator assisted individuals (VAIs) who depend on Home Mechanical Ventilation (HMV) is an escalating public health challenge with important social and economic implications. VAIs are high cost users of the healthcare system, requiring competent healthcare and family caregivers for successful transition to HMV. The TTLive Study …

McMaster Children's Hospital
 (7.5 away) Contact site
  • 0 views
  • 04 Oct, 2022
  • +7 other locations