Brampton, Canada Clinical Trials

A listing of Brampton, Canada clinical trials actively recruiting patients volunteers.

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Found 89 clinical trials
Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis

A Phase 2a, multicenter, 3-part, randomized, double-blind, dose-ranging, placebo-controlled study to evaluate the safety, tolerability, and PK of once-daily treatment with PLN-74809 in participants with idiopathic pulmonary fibrosis.

idiopathic pulmonary fibrosis
diffusion capacity of the lung for carbon monoxide
pirfenidone
nintedanib
Clinical Site
 (8.5 away) Contact site
  • 20 views
  • 26 Aug, 2021
  • +30 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

chronic disease
stroke
semaglutide
Novo Nordisk Investigational Site
 (2.4 away) Contact site
  • 1280 views
  • 12 Aug, 2021
  • +557 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

infarct
arterial disease
diabetes
myocardial infarction
stroke
Brampton Clinical Trials
 (1.7 away) Contact site
  • 542 views
  • 19 Sep, 2021
  • +1332 other locations
Research Study to Compare Three Doses of Semaglutide Tablets Taken Once Daily in People With Type 2 Diabetes

This study compares three doses of once daily semaglutide tablets in people with type 2 diabetes who were previously treated with other oral anti-diabetic medicines. Participants will be initiated on the lowest starting dose of 3 mg and gradually increased until they reach the final trial dose of 14 mg, …

Novo Nordisk Investigational Site
 (2.4 away) Contact site
  • 6 views
  • 19 Sep, 2021
  • +155 other locations
Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial

This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Health Organization. Subjects will be randomized to receive either standard-of-care products or the study medication plus supportive care, while being hospitalized for COVID-19. Participants will be randomized to one of …

hydroxychloroquine
covid-19
lopinavir/ritonavir
SARS
remdesivir
William Osler Health System - Brampton Civic Hospital
 (1.6 away) Contact site
  • 1291 views
  • 31 May, 2021
  • +57 other locations
A Phase 2b Diabetic Kidney Disease Study

A Phase 2b Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Efficacy and Safety of MEDI3506 in Subjects with Diabetic Kidney Disease

diabetic nephropathy
nephropathy
Research Site
 (2.4 away) Contact site
  • 54 views
  • 14 Aug, 2021
  • +115 other locations
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (300/L). Eligible patients must have a history of 2 moderate and/or severe COPD exacerbations in the previous year …

antibiotics
corticosteroids
severe chronic obstructive pulmonary disease
eosinophil count
bronchodilator
Research Site
 (8.5 away) Contact site
  • 838 views
  • 10 Sep, 2021
  • +438 other locations
A Study to Understand Effectiveness and Safety of ABP 938 Compared to Aflibercept (Eylea ) in Patients Suffering With Neovascular Age-related Macular Degeneration [Neovascular (Wet) AMD]

The purpose of this study is to compare the efficacy and safety of ABP 938 versus Aflibercept (Eylea) in the treatment of neovascular age-related macular degeneration. Subjects will be randomized in a masked 1:1 ratio to receive 2 mg (0.05 mL) of either ABP 938 (Treatment Group or aflibercept (Treatment …

Canadian Centre for Advanced Eye Therapeutics Inc
 (9.2 away) Contact site
  • 57 views
  • 15 Sep, 2021
  • +225 other locations
Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

steatohepatitis
fibrosis
hepatic fibrosis
Aggarwal and Associates Limited
 (2.4 away) Contact site
  • 72 views
  • 08 Sep, 2021
  • +350 other locations
Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

This seamless, adaptive, two-stage, Phase 2b/3, randomized, double-blind, multicenter, parallel-groups, placebo-controlled study will assess the efficacy, safety, and tolerability of belapectin compared with placebo in patients with nonalcoholic steatohepatitis (NASH) cirrhosis and clinical signs of portal hypertension but without esophageal varices at baseline.

varicose veins
diabetes
fatty liver
MRI
liver disease
Brampton Civic Hospital
 (1.6 away) Contact site
  • 14 views
  • 18 Sep, 2021
  • +117 other locations