Brampton, Canada Clinical Trials

A listing of Brampton, Canada clinical trials actively recruiting patients volunteers.

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Found 89 clinical trials
Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial

Patients who are critically ill in the in the Intensive Care Unit (ICU), especially those who need a breathing machine, can develop ulcers in the stomach that bleed. To prevent bleeding, many such patients around the world receive a drug called pantoprazole that decreases acid production. However, today, compared to …

resuscitation
William Osler Hospital, McKenzie Health, Brampton Civic Hospital
 (1.6 away) Contact site
  • 285 views
  • 24 Jan, 2021
  • +35 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
hemoglobin a1c
Aggarwal and Associates Ltd
 (2.4 away) Contact site
  • 597 views
  • 12 Sep, 2021
  • +895 other locations
Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA)

RA is a chronic, systemic inflammatory autoimmune disease which requires treatment for a long time period, hence it is important to study the long-term safety and efficacy of the continuous treatment with GSK3196165 over several years. This is a Phase 3, multicenter, parallel group treatment and long-term extension study primarily …

methotrexate
autoimmune disease
folate
rheumatic diseases
folic acid
GSK Investigational Site
 (2.4 away) Contact site
  • 10 views
  • 27 Apr, 2021
  • +117 other locations
Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis

A Phase 2a, multicenter, 3-part, randomized, double-blind, dose-ranging, placebo-controlled study to evaluate the safety, tolerability, and PK of once-daily treatment with PLN-74809 in participants with idiopathic pulmonary fibrosis.

pirfenidone
nintedanib
idiopathic pulmonary fibrosis
diffusion capacity of the lung for carbon monoxide
Clinical Site
 (8.5 away) Contact site
  • 20 views
  • 26 Aug, 2021
  • +30 other locations
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

The researchers are doing this study to look whether the type 2 diabetes medicine, semaglutide, has a positive effect on heart disease. Participants will either get semaglutide tablets or placebo tablets ("dummy" medicine) - which treatment is decided by chance. Participants must take one tablet with water every morning on …

stroke
semaglutide
chronic disease
Novo Nordisk Investigational Site
 (2.4 away) Contact site
  • 1280 views
  • 12 Aug, 2021
  • +557 other locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

stroke
infarct
diabetes
myocardial infarction
arterial disease
Brampton Clinical Trials
 (1.7 away) Contact site
  • 542 views
  • 19 Sep, 2021
  • +1332 other locations
Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial

This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Health Organization. Subjects will be randomized to receive either standard-of-care products or the study medication plus supportive care, while being hospitalized for COVID-19. Participants will be randomized to one of …

lopinavir/ritonavir
remdesivir
SARS
covid-19
hydroxychloroquine
William Osler Health System - Brampton Civic Hospital
 (1.6 away) Contact site
  • 1291 views
  • 31 May, 2021
  • +57 other locations
A Study to Understand Effectiveness and Safety of ABP 938 Compared to Aflibercept (Eylea ) in Patients Suffering With Neovascular Age-related Macular Degeneration [Neovascular (Wet) AMD]

The purpose of this study is to compare the efficacy and safety of ABP 938 versus Aflibercept (Eylea) in the treatment of neovascular age-related macular degeneration. Subjects will be randomized in a masked 1:1 ratio to receive 2 mg (0.05 mL) of either ABP 938 (Treatment Group or aflibercept (Treatment …

Canadian Centre for Advanced Eye Therapeutics Inc
 (9.2 away) Contact site
  • 57 views
  • 15 Sep, 2021
  • +225 other locations
Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)

The study aims to evaluate two, orally administered, investigational agents - PF-06865571 (DGAT2 inhibitor) and the coadministration of PF-06865571 with PF-05221304 (ACC inhibitor). This study is specifically designed to evaluate the effect of a range of doses of DGAT2i alone, and DGAT2i + ACCi, on resolution of NASH or improvement …

hepatic fibrosis
fibrosis
steatohepatitis
Aggarwal and Associates Limited
 (2.4 away) Contact site
  • 72 views
  • 08 Sep, 2021
  • +350 other locations
Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

This seamless, adaptive, two-stage, Phase 2b/3, randomized, double-blind, multicenter, parallel-groups, placebo-controlled study will assess the efficacy, safety, and tolerability of belapectin compared with placebo in patients with nonalcoholic steatohepatitis (NASH) cirrhosis and clinical signs of portal hypertension but without esophageal varices at baseline.

ultrasound liver
vasectomy
varicose veins
liver disease
cirrhosis
Brampton Civic Hospital
 (1.6 away) Contact site
  • 14 views
  • 18 Sep, 2021
  • +117 other locations