Brampton, Canada Clinical Trials

A listing of Brampton, Canada clinical trials actively recruiting patients volunteers.

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Found 45 clinical trials
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (9.4 away) Contact site
  • 21 views
  • 16 Jul, 2021
  • +470 other locations
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

solid tumour
EGFR
lung carcinoma
cancer treatment
stage iv non-small cell lung cancer
William Osler Health System
 (1.6 away) Contact site
  • 27 views
  • 25 Jul, 2021
  • +324 other locations
A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

The primary purpose of this study is to assess the long-term safety of nemolizumab (CD14152) in participants with prurigo nodularis (PN).

Galderma Investigational Site
 (9.4 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +140 other locations
Atogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments.

This study will assess the safety, tolerability, and efficacy of Atogepant 60 mg compared with placebo in episodic migraines in participants who previously failed 2 to 4 classes of oral prophylactic treatments.

Aggarwal and Associates Limited
 (2.4 away) Contact site
  • 0 views
  • 19 Jul, 2021
  • +134 other locations
Efficacy and Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis

The main purpose of the study is to assess the efficacy and safety of nemolizumab after a 16-week treatment period in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD) not adequately controlled with topical treatments.

Galderma Investigational Site
 (9.4 away) Contact site
  • 95 views
  • 16 Jul, 2021
  • +458 other locations
Safety Tolerability and Efficacy of Cilofexor in Non-Cirrhotic Adults With Primary Sclerosing Cholangitis

The primary objective of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing cholangitis (PSC).

cilofexor
platelet count
fibrosis
William Osler Health System - Brampton Civic Hospital
 (1.6 away) Contact site
  • 83 views
  • 25 Jul, 2021
  • +231 other locations
Phase 2B Study to Evaluate the Efficacy of PB2452 in Reversal of Ticagrelor in Subjects Aged 50-80 Years Old

This phase 2B study is a multi-center, randomized, double-blind, placebo-controlled study. The study is designed to evaluate the efficacy of PB2452 in reversing the anti-platelet effects of ticagrelor as part of a dual antiplatelet regimen and to evaluate the safety and tolerability of PB2452 in subjects aged 50-80 years old. …

BioPharma Services Inc.
 (9.9 away) Contact site
  • 0 views
  • 15 Jul, 2021
  • +14 other locations
A Study of the Efficacy and Safety of Upadacitnib (ABT-494) in Participants With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Conventional and/or Biologic Therapies

The objective of this study is to evaluate the efficacy and safety of upadacitinib compared to placebo as induction therapy in participants with moderately and severely active Crohn's disease (CD).

immunosuppressive agents
conventional treatment
abdominal pain
endoscopy
crohn's disease
Toronto Digestive Disease Asso /ID# 166972
 (10.0 away) Contact site
  • 824 views
  • 21 Jul, 2021
  • +834 other locations
A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

This study will test an experimental drug (enfortumab vedotin) alone and with different combinations of anticancer therapies. Pembrolizumab is an immune checkpoint inhibitor (CPI) that is used to treat patients with cancer of the urinary system (urothelial cancer). This type of cancer includes cancer of the bladder, renal pelvis, ureter …

enfortumab vedotin
platinum-based chemotherapy
intravesical bcg
intravesical chemotherapy
metastasis
Site CA11008
 (1.6 away) Contact site
  • 284 views
  • 23 Jul, 2021
  • +92 other locations
Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension

This study will evaluate the intraocular pressure-lowering effect and safety of Bimatoprost SR compared with selective laser trabeculoplasty in patients with open-angle glaucoma or ocular hypertension who are not adequately managed with topical IOP-lowering medication.

brimonidine tartrate ophthalmic solution
bimatoprost
selective laser trabeculoplasty
intraocular pressure
hypertension
Ophthalmic Consultant Centres
 (9.2 away) Contact site
  • 0 views
  • 21 Jul, 2021
  • +130 other locations