Brampton, Ontario, Canada Clinical Trials

A listing of Brampton, Ontario, Canada clinical trials actively recruiting patients volunteers.

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Found 35 clinical trials
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C3711005  

The study will evaluate the effect of coadministration of a range of doses of DGAT2i with 1 dose of ACCi, on hepatic steatosis and the ability of DGAT2i to mitigate ACCi-induced elevations in serum triglycerides. The study has a 2-part design with sequential conduct of Part 1 and Part 2 …

Aggarwal and Associates Limited
 (2.3 away)
  • 25 views
  • 03 Aug, 2021
  • +10 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site
 (9.4 away) Contact site
  • 21 views
  • 04 Aug, 2021
  • +474 other locations
A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

The primary purpose of this study is to assess the long-term safety of nemolizumab (CD14152) in participants with prurigo nodularis (PN).

Galderma Investigational Site
 (9.4 away) Contact site
  • 0 views
  • 30 Jul, 2021
  • +140 other locations
Safety Tolerability and Efficacy of Cilofexor in Non-Cirrhotic Adults With Primary Sclerosing Cholangitis

The primary objective of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing cholangitis (PSC).

platelet count
cilofexor
fibrosis
William Osler Health System - Brampton Civic Hospital
 (1.6 away) Contact site
  • 83 views
  • 25 Jul, 2021
  • +231 other locations
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

epidermal growth factor receptor
lung carcinoma
stage iv non-small cell lung cancer
growth factor
solid tumour
William Osler Health System
 (1.6 away) Contact site
  • 27 views
  • 02 Aug, 2021
  • +325 other locations
CT-Perfusion for Neurological Diagnostic Evaluation

For the purpose of organ donation after neurological determination of death (NDD), death must be declared using a set of standardized clinical criteria. When a full clinical evaluation cannot be completed, additional neuroimaging ancillary testing is required. The ideal ancillary test for NDD would demonstrate no cerebral blood flow, be …

William Osler Health System
 (1.6 away) Contact site
  • 727 views
  • 01 Aug, 2021
  • +18 other locations
A Multicenter Randomized Double-Blind Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2. The objective of Sub-Study 2 is to …

remission
Toronto Digestive Diseases Ass /ID# 169106
 (10.0 away) Contact site
  • 611 views
  • 04 Aug, 2021
  • +890 other locations
Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension

This study will evaluate the intraocular pressure-lowering effect and safety of Bimatoprost SR compared with selective laser trabeculoplasty in patients with open-angle glaucoma or ocular hypertension who are not adequately managed with topical IOP-lowering medication.

intraocular pressure
hypertension
trabeculectomy
bimatoprost
glaucoma
Ophthalmic Consultant Centres
 (9.2 away) Contact site
  • 3 views
  • 21 Jul, 2021
  • +130 other locations
An Induction Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 1)

The purpose of this study is to evaluate the safety and efficacy of Mirikizumab in participants with moderately to severely active ulcerative colitis (UC) who have had an inadequate response to, loss of response, or intolerant to conventional or biologic therapy for UC.

mirikizumab
Toronto Digestive Disease Associates, Inc.
 (10.0 away) Contact site
  • 1722 views
  • 24 Jul, 2021
  • +880 other locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

mirikizumab
endoscopy
Toronto Digestive Disease Associates, Inc.
 (10.0 away) Contact site
  • 386 views
  • 26 Jul, 2021
  • +906 other locations