Ayr, Canada Clinical Trials

A listing of Ayr, Canada clinical trials actively recruiting patients volunteers.

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Found 15 clinical trials
Efficacy and Safety of Etripamil for the Termination of Spontaneous PSVT. NODE 301 [Part 1 and Part 2 (The RAPID Study)]

This is a two-part, multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of etripamil NS self-administered by patients who experience an episode of paroxysmal ventricular tachycardia (PSVT) in an at-home setting. Part 1 comprised the conduct of the NODE-301 study up to the date of the adjudication …

Cambridge Cardiac Care Centre
 (9.2 away) Contact site
  • 281 views
  • 05 May, 2021
  • +127 other locations
Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303

NODE-303 is a multi-center, open label (OL) study to evaluate the safety of etripamil NS in patients with Paroxysmal Supraventricular Tachycardia (PSVT). Patients will be provided with an ambulatory Cardiac Monitoring System (CMS) to help document PSVT episodes. The CMS will be self-applied by the patient, when PSVT symptoms begin. …

0215
 (9.2 away) Contact site
  • 109 views
  • 27 Jan, 2021
  • +146 other locations
Peer Administered Online CBT for PPD

Postpartum depression (PPD) affects up to one in five of women and has profound effects on mothers and their infants. Unfortunately, fewer than 15% of women with PPD receive evidence-based care. This is at least partly due to significant difficulties faced by women in accessing psychotherapies, their preferred treatment for …

depressed mood
behavior therapy
Kids Can Fly
 (9.6 away) Contact site
  • 0 views
  • 03 Jul, 2021
  • 1 location
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

ejection fraction
bypass graft
cardiac resynchronization therapy
b-type natriuretic peptide
iron
Vizel Cardiac Research
 (8.9 away) Contact site
  • 5316 views
  • 22 Jul, 2021
  • +365 other locations
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. …

body mass index
cardiovascular disease
overweight or obesity
Novo Nordisk Investigational Site
 (9.2 away) Contact site
  • 7712 views
  • 18 Jul, 2021
  • +1164 other locations
Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer

Primary Objective: To determine whether amcenestrant per os improves progression free survival (PFS) when compared with a endocrine monotherapy of the choice of the physician, in participants with metastatic or locally advanced breast cancer Secondary Objectives: To compare the overall survival in the 2 treatment arms To assess the objective …

estrogen receptor
hormone therapy
estrogen
immunological adjuvant
advanced breast cancer
Investigational Site Number 1240002
 (8.8 away) Contact site
  • 213 views
  • 13 Jun, 2021
  • +168 other locations
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%

The purpose of this study is to evaluate the effect of finerenone compared to placebo (a tablet without active substance) in the reduction of cardiovascular death (generally meaning death due to disease of the heart or blood vessels) and total Heart Failure (HF) events, including HF hospitalization and urgent visits …

ejection fraction
stroke
b-type natriuretic peptide
heart disease
heart failure
Vizel Cardiac Research
 (8.9 away) Contact site
  • 0 views
  • 03 Jul, 2021
  • +774 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
cardiovascular disease
hemoglobin a1c
Cambridge Cardiac Care Centre
 (9.2 away) Contact site
  • 593 views
  • 21 Jul, 2021
  • +887 other locations
Efficacy Safety and Tolerability of AZD9977 and Dapagliflozin in Participants With Heart Failure and Chronic Kidney Disease

The purpose of the study is to evaluate the efficacy and safety of AZD9977 alone and AZD9977 in combination with dapagliflozin and to assess the dose-response relationship of placebo, AZD9977 alone, dapagliflozin alone and 3 doses of AZD9977 combined with dapagliflozin on urinary albumin to creatinine ratio (UACR). The study …

loop diuretic
antihypertensive drugs
MRI
b-type natriuretic peptide
hypertension
Research Site
 (8.6 away) Contact site
  • 0 views
  • 10 Jul, 2021
  • +135 other locations
Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation

The purpose of the ANT-006 study is to evaluate the bleeding profile of abelacimab relative to rivaroxaban in patients with atrial fibrillation (AF) at moderate-to-high risk of stroke.

anticoagulation therapy
stroke
atrial flutter
fibrillation
aspirin
Anthos Investigative Site
 (8.9 away) Contact site
  • 0 views
  • 22 Jul, 2021
  • +52 other locations