St. John's , Canada Clinical Trials

A listing of St. John's , Canada clinical trials actively recruiting patients volunteers.

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Found 26 clinical trials
Efficacy and Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis

The main purpose of the study is to assess the efficacy and safety of nemolizumab after a 16-week treatment period in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD) not adequately controlled with topical treatments.

Galderma Investigational Site
 (0.5 away) Contact site
  • 95 views
  • 16 Jul, 2021
  • +458 other locations
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis

Long-Term Safety and Efficacy of Nemolizumab in Subjects with Moderate-to-Severe Atopic Dermatitis Description

Galderma Investigational Site 8000
 (0.5 away) Contact site
  • 21 views
  • 16 Jul, 2021
  • +470 other locations
A Study to Assess the Efficacy Safety and Tolerability of Rozanolixizumab in Adult Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP)

The purpose of this study is to demonstrate the clinical efficacy of rozanolixizumab in maintenance treatment and assess safety and tolerability of rozanolixizumab in adult study participants with primary immune thrombocytopenia (ITP).

Tp0006 50384
 (1130.5 away) Contact site
  • 15 views
  • 11 Jul, 2021
  • +49 other locations
Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

Psoriasis (PsO) is a chronic disease characterized by marked inflammation of the skin that results in thick, red, scaly plaques. This study will assess how safe and effective risankizumab is compared to apremilast in adult participants with moderate plaque psoriasis. Adverse events and change in disease symptoms will be monitored. …

arthritis
risankizumab
plaque psoriasis
systemic therapy
apremilast
Karma Clinical Trials /ID# 230339
 (3.5 away) Contact site
  • 0 views
  • 22 Jul, 2021
  • +61 other locations
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced ejection fraction and with iron deficiency

ejection fraction
nesiritide
heart failure
iron
natriuretic peptide
Health Sciences Centre
 (1.6 away) Contact site
  • 5316 views
  • 22 Jul, 2021
  • +365 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

stroke
infarct
stemi
diabetes
acute coronary syndrome
1240060 - Health Sciences Centre
 (1.6 away) Contact site
  • 1118 views
  • 21 Jul, 2021
  • +3430 other locations
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming …

tamoxifen
hormone therapy
endocrine therapy
HER2
immunostimulant
Doctor H. Bliss Murphy Cancer Centre
 (1.6 away) Contact site
  • 591 views
  • 21 Jul, 2021
  • +318 other locations
Efficacy and Safety Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis

This is a Phase 3, multicenter, randomized, placebo-controlled, double-blind study of the efficacy and safety of apremilast (CC-10004) in pediatric subjects with moderate to severe plaque psoriasis. At least 230 pediatric subjects (ages 6 through 17 years) will be randomized 2:1 to receive either apremilast or placebo for the first …

phototherapy
topical agents
plaque psoriasis
systemic therapy
cc-10004
Karma Clinical Trials
 (3.5 away) Contact site
  • 98 views
  • 22 Jul, 2021
  • +284 other locations
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (300/L). Eligible patients must have a history of 2 moderate and/or severe COPD exacerbations in the previous year …

corticosteroids
bronchodilator
antibiotics
eosinophil count
severe chronic obstructive pulmonary disease
Research Site
 (555.8 away) Contact site
  • 832 views
  • 10 Jul, 2021
  • +426 other locations
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors

This study will test how well a new medicine called concizumab works in the body of people with haemophilia A or B without inhibitors. The purpose is to show that concizumab can prevent bleeds in the body and is safe to use. Participants who usually only take medicine to treat …

Novo Nordisk Investigational Site
 (1.6 away) Contact site
  • 36 views
  • 22 Jul, 2021
  • +104 other locations