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A, Woolloongabba N Clinical Trials

A listing of A, Woolloongabba N clinical trials actively recruiting patients volunteers.

RESULTS

Found (88) clinical trials

Capecitabine and Temozolomide for Treatment of Recurrent Pituitary Adenomas

This is an open label study to assess the efficacy of capecitabine (CAP) and temozolomide (TMZ) in recurrent pituitary adenomas. There will be a safety run-in of at least three patients to establish any dose limiting toxicities. Enrolled patients will receive treatment in 28-day cycles: capecitabine 1500mg/m2 per day (divided ...

Phase

Effect of Vitamin C in Autologous Stem Cell Transplantations

Rationale: Recent studies showed that ascorbic acid (AA) stimulates proliferation and maturation of T lymphocytes and natural killer (NK) cells. Chemotherapy results in depletion of those cells and thereby an increased infection rate. A pilot study showed low levels of AA in the plasma of several patients after chemotherapy followed ...

Phase

Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17

PRIMARY OBJECTIVES To evaluate the efficacy (adequate response) after 2 cycles of BEABOVP (bendamustine substitution for mechlorethamine in the original Stanford V chemotherapy backbone) in low-risk and intermediate-risk patients with classical Hodgkin lymphoma (cHL). To estimate the event-free survival in high-risk patients with classical Hodgkin lymphoma (cHL). SECONDARY OBJECTIVES To ...

Phase

Mepo for EoE Study

This is a multi-center, randomized, double blind, parallel-arm, placebo controlled trial of mepolizumab. After the first 3 month blinded phase, there will be a second 3 month blinded phase where all patients receive active medication, but the dose will be lower in the subjects initially randomized to the placebo arm. ...

Phase

FORWARD Optune and Adjuvant TMZ in Grade II/III Astrocytoma

Patients with newly diagnosed high-risk Grade II or II astrocytoma must undergo maximal safe resection (biopsy alone may be eligible) and chemoradiotherapy: concomitant 75mg/m2 daily temozolomide with 80% prescribed dose completed and RT with minimal RT dose of 40 Gy delivered. Within three weeks prior to beginning adjuvant temozolomide, all ...

Phase

Efficacy Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression

This is a randomized, multiple dose, placebo-controlled, double-blind, multicentre study of Esketamine DPI, inhalation powder delivered via dry powder inhaler (DPI) in participants with TRBD. There are 3 study phases: Screening phase, a two weeks double-blind treatment phase and a 6-week follow-up phase. Participants are to be randomized in 1:1:1:1 ...

Phase

Trial Evaluating the Efficacy of Systemic Mesenchymal Stromal Cell (MSC) Injections for the Treatment of Severe and Chronic Radiotherapy-induced Abdomino-pelvic Complications (Pelvic Radiation Disease PRD) Refractory to Standard Therapy

-Chemo-radiation enhances survival but also increases the risk of PRD. The result will be an increasing Cost for society (repeated hospitalization for palliative care) An ethical problem to help these patients with irreversible degraded quality of life. Results from conventional therapies for PRD reveal a poor long-term efficacy: i. Coagulation ...

Phase

Micronised Resveratrol as a Treatment for Friedreich Ataxia

Friedreich ataxia (FRDA) is the most common hereditary ataxia, with an estimated prevalence in Caucasians of 1 in 30,000. Neurological features of FRDA are progressive gait and limb ataxia, absent lower limb reflexes, and loss of position and vibration sense. There are currently no treatments proven to alter the natural ...

Phase

Serial Infusions of Allogeneic Mesenchymal Stem Cells in Ischemic Cardiomyopathy Patients With Left Ventricular Assist Device

A double-blind, placebo-controlled, single-center, randomized study to assess the safety and preliminary efficacy of a three serial intravenous doses of allogeneic mesenchymal bone marrow cells to subjects with heart failure of ischemic etiology and implanted left ventricular assist devices.

Phase

Study the Efficacy and Safety of VAY736 and CFZ533 in SLE Patients

This study is designed to evaluate the safety, tolerability, pharmacokinetics and therapeutic efficacy of treatment with either VAY736 or CFZ533 in patients with SLE to enable further development of these compounds as treatment in this disease population

Phase