St Kilda, VIC, Australia Clinical Trials

A listing of St Kilda, VIC, Australia clinical trials actively recruiting patients volunteers.

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Found 162 clinical trials
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A Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination With Ruxolitinib in Participants With Myelofibrosis

www.MyelofibrosisResearch.com This is a Phase 2 open-label, multicenter study evaluating tolerability and efficacy of navitoclax alone or when added to ruxolitinib in participants with myelofibrosis.

The Alfred Hospital /ID# 215545
 (1.2 away) Contact site
  • 251 views
  • 29 Apr, 2021
  • +134 other locations
Trial of EXenatide in Acute Ischaemic Stroke

Overview: Elevated blood glucose levels are common in many acute diseases, resulting in worse clinical outcomes. Hyperglycaemia in acute ischaemic stroke (post-stroke hyperglycaemia [PSH]) occurs in up to 50% patients, reduces the efficacy of stroke thrombolysis with increased risk of haemorrhage, increases infarct size, and results in worse clinical outcomes …

Alfred Hospital
 (2.3 away) Contact site
  • 2 views
  • 23 Jan, 2021
  • +15 other locations
Phase ll Study of Pirfenidone in Patients With RAILD (TRAIL1)

The purpose of this study is to to assess the safety and tolerability of pirfenidone 2403 mg/day for the treatment of RA-associated interstitial lung disease.

Melbourne Alfred Hospital
 (2.3 away) Contact site
  • 207 views
  • 23 Jan, 2021
  • +30 other locations
Study of REGN2810 in Patients With Advanced Cutaneous Squamous Cell Carcinoma

For Groups 1 to 4, the primary objective of this study is to estimate the clinical benefit of cemiplimab monotherapy for patients with: metastatic (nodal or distant) cutaneous squamous cell carcinoma (CSCC), or unresectable locally advanced CSCC. For Group 6, the primary objective is to provide additional efficacy and safety …

Peter MacCallum Cancer Centre
 (3.5 away) Contact site
  • 0 views
  • 28 Jan, 2021
  • +102 other locations
A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity

This is an open-label, multi-institutional phase II randomized study comparing neoadjuvant radiotherapy followed by surgical resection to neoadjuvant pembrolizumab with concurrent radiotherapy, followed by surgical resection and adjuvant pembrolizumab. The total duration of pembrolizumab will be one year in the experimental arm.

Peter MacCallum Cancer Centre
 (3.5 away) Contact site
  • 56 views
  • 23 Jan, 2021
  • +16 other locations
A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

The purpose of the study is to evaluate on-treatment efficacy against hepatitis D virus (HDV) of JNJ-73763989 + nucleos(t)ide analog (NA) regimen compared to NA alone.

Eastern Health Research
 (8.3 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +69 other locations
Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)

The purpose of this Phase II study is to assess the efficacy and safety of NIS793 with and without spartalizumab in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel in untreated mPDAC.

Novartis Investigative Site
 (3.5 away) Contact site
  • 0 views
  • 12 Jun, 2021
  • +23 other locations
Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis

In this study researchers want to learn about the safety of drug Osocimab at low and high doses in adult participants with kidney disease undergoing regular dialysis (a procedure that uses a machine to get rid of toxins and extra fluids in the blood). Patients with kidney disease undergoing regular …

Eastern Health Integrated Renal Service
 (8.3 away) Contact site
  • 20 views
  • 28 May, 2021
  • +215 other locations
Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer

This study will evaluate the efficacy, safety, and pharmacokinetics of Trastuzumab deruxtecan (T-DXd) in participants with human epidermal growth factor 2 (HER2)-overexpressing locally advanced, unresectable, or metastatic colorectal cancer (mCRC).

Peter MacCallum Cancer Centre
 (3.6 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +63 other locations
Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

This is an open-label, randomized, multi-center, comparator Phase II trial looking at the addition of Bevacizumab to Vinblastine in chemotherapy nave pediatric patients with progressive Low Grade Glioma aged 6 months to less than18 years of age at the time of initiation of therapy. Participants will be randomized to Arm …

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Royal Children's Hospital
 (6.2 away) Contact site
  • 0 views
  • 24 Jan, 2021
  • +23 other locations