North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 12 clinical trials
Prevention of Postoperative Events Following Reversal With Sugammadex or Neostigmine

The purpose of this study is to determine if the use of sugammadex (compared with neostigmine) reduces the rate of postoperative pulmonary complications (PPCs).

neostigmine
Royal North Shore Hospital
 (4.8 away) Contact site
  • 32 views
  • 03 Sep, 2020
  • 1 location
Study to Evaluate Discontinuation and Re-Treatment in Participants With Tenosynovial Giant Cell Tumor (TGCT) Previously Treated With Pexidartinib

This study is designed to evaluate the discontinuation/re-treatment of pexidartinib therapy in previously treated participants with tenosynovial giant cell tumor (TGCT).

Chris O'Brien Lifehouse
 (7.3 away) Contact site
  • 0 views
  • 28 Oct, 2020
  • +11 other locations
Plasma-Lyte 148 versUs Saline Study

The aim of PLUS is to conduct a multi-centre, blinded, randomised, controlled trial (RCT) to determine whether fluid resuscitation and therapy with a "balanced" crystalloid solution (Plasma-Lyte 148) decreases 90-day mortality in critically ill patients requiring fluid resuscitation when compared with the same treatment using 0.9% sodium chloride (saline)

Concord Repatriation General Hospital
 (3.5 away) Contact site
  • 0 views
  • 04 Oct, 2020
  • +52 other locations
Efficacy Safety and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)

This study will evaluate the efficacy, safety, and pharmacokinetics (PK) of sugammadex (MK-8616) for reversal of both moderate and deep neuromuscular blockade (NMB) in pediatric participants aged birth to <2 years. The primary hypothesis of this study is that sugammadex is superior to neostigmine in reversing moderate NMB as measured …

glycopyrrolate
neostigmine
intubation
atropine
sugammadex
The Children s Hospital at Westmead ( Site 3805)
 (7.7 away) Contact site
  • 4 views
  • 28 Oct, 2020
  • +27 other locations
A Sourcing Study to Collect Human Blood Samples From Healthy Adults

The purpose of this study is to collect large volumes of matched pairs of pre- and post-vaccination sera from healthy subjects who will be administered GlaxoSmithKline (GSK) Biologicals' vaccine against meningitis- MenACWY vaccine (Menveo) or rMenB+OMV NZ vaccine (Bexsero), which will serve for the development, qualification, validation and maintenance of …

menveo
hysterectomy
vaccination
bexsero
menacwy
GSK Investigational Site
 (8.2 away) Contact site
  • 721 views
  • 22 Oct, 2020
  • +6 other locations
Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY Disease

The Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY disease (CLARITY) study is a pragmatic prospective, open-label, randomised controlled trial. CLARITY aims to examine the effectiveness of angiotensin II receptor blockers (ARBs) on improving the outcomes of people who tested positive for COVID-19 disease.

SARS
diabetes
angiotensin
covid-19
Concord Hospital
 (4.4 away) Contact site
  • 64 views
  • 23 Jul, 2020
  • +10 other locations
Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis (PBC) is a serious, life-threatening, bile acid related liver disease of unknown cause. Without treatment, it frequently progresses to liver fibrosis and eventual cirrhosis requiring liver transplantation or resulting in death. The investigational drug, Obeticholic Acid (OCA) is a modified bile acid and FXR agonist that is …

liver transplant
antimitochondrial antibody
chenodeoxycholic acid
ursodiol
investigational drug
Royal Prince Alfred Hospital
 (7.5 away) Contact site
  • 402 views
  • 14 Oct, 2020
  • +322 other locations
Long-Term Outcomes and Durability of Effect Following Treatment With Cladribine Tablets for Multiple Sclerosis (MS)

The purpose of this study is to explore the long-term outcomes, durability of effect, and real world treatment patterns in participants previously participating in the Phase 3 oral cladribine in early multiple sclerosis (ORACLE MS) and Oral Cladribine in participants with relapsing remitting multiple sclerosis, extension study (CLARITY/CLARITY-EXT) clinical trials …

cladribine
relapsing multiple sclerosis
University of Sydney
 (7.3 away) Contact site
  • 331 views
  • 25 Nov, 2020
  • +81 other locations
A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Study 20170703 is a phase 4, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of erenumab against placebo in subjects with chronic migraine (CM) who have a history of at least 1 preventive treatment failure and are diagnosed with medication overuse headache (MOH).

headache
common migraine
chronic migraine
migraine with aura
erenumab
Research Site
 (7.3 away) Contact site
  • 359 views
  • 04 Nov, 2020
  • +75 other locations
Randomized Embedded Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of patients admitted to intensive care with community-acquired pneumonia. In addition, REMAP-CAP provides and adaptive research platform for evaluation of …

Royal North Shore Hospital
 (5.0 away) Contact site
  • 2104 views
  • 18 Oct, 2020
  • +107 other locations