North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 220 clinical trials
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A Study to Evaluate the Safety and Tolerability of ABBV-951 in Subjects With Parkinson's Disease (PD)

The purpose of this study is to assess the safety and tolerability of ABBV-951 in subjects with Parkinson's disease (PD).

levodopa
Concord Repatriation & Gen Hos /ID# 207628
 (4.4 away) Contact site
  • 395 views
  • 18 May, 2020
  • +20 other locations
featured
A Phase III, Randomised, Double Blind, Placebo Controlled, Multicentre Study of Maintenance Olaparib Monotherapy in Patients With gBRCA Mutated Metastatic Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum Based Chemotherapy

A Phase III, Randomised, Double Blind, Placebo Controlled, Multicentre Study of Maintenance Olaparib Monotherapy in Patients With gBRCA Mutated Metastatic Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum Based Chemotherapy

Royal North Shore Hospital
 (4.8 away) Contact site
  • 326 views
  • 08 Nov, 2020
  • +26 other locations
Androgen Deprivation Therapy in Treating Patients With Prostate Cancer

RATIONALE: Androgens can cause the growth of prostate cancer cells. Androgen deprivation therapy may stop the adrenal glands from making androgens. PURPOSE: This randomized phase III trial is studying how well androgen deprivation therapy works in treating patients with prostate cancer.

androgen suppression
epinephrine
antiandrogen therapy
antiandrogens
androgens
Sydney Cancer Centre at Royal Prince Alfred Hospital
 (7.5 away) Contact site
  • 401 views
  • 07 Nov, 2020
  • +8 other locations
Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers

We hypothesize through this randomized, placebo-controlled adjuvant study, that Aspirin in patients with dukes C or high risk dukes B colorectal cancer (ASCOLT) can improve survival in this patient population over placebo control. If indeed found to be beneficial, because aspirin is cheap and easy to administer, it will positively …

aspirin
colon cancer
PIK3CA
rectal carcinoma
Northern Cancer Institute, St Leonards
 (4.8 away) Contact site
  • 646 views
  • 07 Nov, 2020
  • +42 other locations
Pembrolizumab Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

This is a randomized, double-blind, study that compares pembrolizumab with placebo given as adjuvant therapy in participants with high-risk locally advanced cutaneous squamous cell carcinoma (LA cSCC) that have undergone surgery with curative intent in combination with radiotherapy. The primary hypothesis is that pembrolizumab is superior to placebo in increasing …

pembrolizumab
cancer
mk-3475
adjuvant therapy
Royal North Shore Hospital ( Site 0052)
 (4.8 away) Contact site
  • 69 views
  • 03 Dec, 2020
  • +127 other locations
Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

A Global Study to Determine the Efficacy and Safety of Durvalumab in Combination with Gemcitabine+Cisplatin for Neoadjuvant Treatment and Durvalumab Alone for Adjuvant Treatment in Patients with Muscle-Invasive Bladder Cancer

Research Site
 (1.3 away) Contact site
  • 147 views
  • 24 Nov, 2020
  • +244 other locations
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

The purpose of this study is to evaluate efficacy of erdafitinib versus chemotherapy or pembrolizumab in participants with advanced urothelial cancer harboring selected fibroblast growth factor receptor (FGFR) aberrations who have progressed after 1 or 2 prior treatments, at least 1 of which includes an anti-PD-(L) 1 agent (cohort 1) …

growth factor
adjuvant chemotherapy
erdafitinib
pembrolizumab
advanced urothelial carcinoma
Chris O'Brien Lifehouse
 (7.5 away) Contact site
  • 271 views
  • 12 Oct, 2020
  • +522 other locations
Safety Tolerability and Efficacy of Cilofexor in Non-Cirrhotic Adults With Primary Sclerosing Cholangitis

The primary objective of this study is to evaluate whether cilofexor reduces the risk of fibrosis progression among non-cirrhotic adults with primary sclerosing cholangitis (PSC).

fibrosis
cilofexor
platelet count
Royal Prince Alfred Hospital
 (7.3 away) Contact site
  • 83 views
  • 29 Nov, 2020
  • +217 other locations
Efficacy Safety and Tolerability of Atogepant for the Prevention of Chronic Migraine

This study will evaluate the efficacy, safety and tolerability of atogepant in participants with chronic migraine. This study includes a 12-week treatment period.

headache
migraine
Royal North Shore Hospital
 (4.8 away) Contact site
  • 576 views
  • 01 Nov, 2020
  • +146 other locations
Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile Infection

Summit is developing ridinilazole as a novel antimicrobial for Clostridium difficile Infection (CDI) with the goal of achieving comparable cure rates to standard of care, but reducing rates of recurrent disease. A phase 2 proof of concept study, with vancomycin as comparator, demonstrated these attributes with a comparable safety profile. …

antibiotic therapy
antibiotics
vancomycin
clostridium difficile
ridinilazole
Westmead Hospital
 (7.9 away) Contact site
  • 101 views
  • 08 Jul, 2020
  • +223 other locations