North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 5 clinical trials
Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Versus Chemotherapy for Endometrial Carcinoma (ENGOT-en9 / MK-7902-001)

The purpose of this study is to compare the efficacy of pembrolizumab + lenvatinib to chemotherapy in female participants with Stage III, IV, or recurrent endometrial carcinoma. It is hypothesized that the combination of pembrolizumab + lenvatinib will be superior to chemotherapy for progression-free survival (PFS) per Response Evaluation Criteria …

paclitaxel
pembrolizumab
mk-3475
solid tumour
endometrial carcinoma
Royal North Shore Hospital ( Site 1600)
 (4.8 away) Contact site
  • 403 views
  • 02 Dec, 2020
  • +212 other locations
Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients

ICON 9 will assess the efficacy, safety and tolerability of maintenance olaparib in combination with cediranib compared to maintenance olaparib alone following a response to platinum-based chemotherapy in women with relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer. Prognostic and predictive factors will be studied from tumour and blood samples.

fallopian tube
metastasis
bevacizumab
peritoneal cancer
recurrent disease
Calvary Mater Hospital
 (7.3 away) Contact site
  • 392 views
  • 16 Sep, 2020
  • +40 other locations
Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)

Urinary tract infections (UTIs; acute cystitis) are very common, with approximately 11 percentage of women (>18 years of age) reporting at least 1 episode of acute cystitis per year. The purpose of this study to evaluate the therapeutic response (combined microbiological and clinical efficacy per participant) of oral gepotidacin compared …

gepotidacin
leukocyte esterase
cystitis
acute cystitis
nitrite
GSK Investigational Site
 (7.3 away) Contact site
  • 394 views
  • 21 Nov, 2020
  • +96 other locations
Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11)

The purpose of this study is to evaluate the efficacy and safety of pembrolizumab plus concurrent chemoradiotherapy compared to placebo plus concurrent chemoradiotherapy in participants with locally advanced cervical cancer. The primary hypotheses are that pembrolizumab plus concurrent chemoradiotherapy is superior to placebo plus concurrent chemoradiotherapy with respect to progression-free …

chemoradiotherapy
adenocarcinoma
adenosquamous carcinoma
pembrolizumab
external beam radiation therapy
Westmead Hospital ( Site 0973)
 (7.7 away) Contact site
  • 85 views
  • 02 Dec, 2020
  • +91 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

sarcoma
paclitaxel
olaparib
recurrent disease
maintenance therapy
Research Site
 (8.2 away) Contact site
  • 104 views
  • 29 Nov, 2020
  • +163 other locations