North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 111 clinical trials
Phase ll Study of Pirfenidone in Patients With RAILD (TRAIL1)

The purpose of this study is to to assess the safety and tolerability of pirfenidone 2403 mg/day for the treatment of RA-associated interstitial lung disease.

Royal Prince Alfred Hospital
 (7.5 away) Contact site
  • 207 views
  • 08 Jul, 2019
  • +30 other locations
A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity

This is an open-label, multi-institutional phase II randomized study comparing neoadjuvant radiotherapy followed by surgical resection to neoadjuvant pembrolizumab with concurrent radiotherapy, followed by surgical resection and adjuvant pembrolizumab. The total duration of pembrolizumab will be one year in the experimental arm.

Chris O'Brien Hospital
 (7.5 away) Contact site
  • 56 views
  • 27 Jan, 2020
  • +16 other locations
Study of REGN2810 in Patients With Advanced Cutaneous Squamous Cell Carcinoma

For Groups 1 to 4, the primary objective of this study is to estimate the clinical benefit of cemiplimab monotherapy for patients with: metastatic (nodal or distant) cutaneous squamous cell carcinoma (CSCC), or unresectable locally advanced CSCC. For Group 6, the primary objective is to provide additional efficacy and safety …

Royal North Shore Hospital
 (4.8 away) Contact site
  • 0 views
  • 17 Nov, 2020
  • +100 other locations
Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

This is an open-label, randomized, multi-center, comparator Phase II trial looking at the addition of Bevacizumab to Vinblastine in chemotherapy nave pediatric patients with progressive Low Grade Glioma aged 6 months to less than18 years of age at the time of initiation of therapy. Participants will be randomized to Arm …

platelet count
vinblastine
glomerular filtration rate
auditory test
neutrophil count
Children's Hospital at Westmead
 (7.7 away) Contact site
  • 0 views
  • 16 Mar, 2020
  • +22 other locations
Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)

This study will evaluate the efficacy and safety of olaparib (MK-7339) monotherapy in participants with multiple types of advanced cancer (unresectable and/or metastatic) that: 1) have progressed or been intolerant to standard of care therapy; and 2) are positive for homologous recombination repair mutation (HRRm) or homologous recombination deficiency (HRD).

Kinghorn Cancer Centre ( Site 2200)
 (8.2 away) Contact site
  • 135 views
  • 02 Dec, 2020
  • +142 other locations
Safety Tolerability and Efficacy of the Human Cytomegalovirus Vaccine (V160) in Healthy Women 16 to 35 Years of Age (V160-002)

This study will evaluate the safety, tolerability, and efficacy of Human Cytomegalovirus (CMV) vaccine V160 administered in a 2-dose or 3-dose regimen in healthy seronegative women 16 to 35 years of age. Participants will receive blinded V160 on Day 1, Month 2, and Month 6 (3-dose regimen), V160 on Day …

Holdsworth House Medical Practice ( Site 0241)
 (8.2 away) Contact site
  • 6476 views
  • 12 Aug, 2019
  • +95 other locations
A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201)

The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with advanced/metastatic Merkel cell carcinoma (MCC).

St Vincent's Hospital Sydney
 (8.2 away) Contact site
  • 21 views
  • 11 Nov, 2020
  • +74 other locations
Study of Efficacy Safety Tolerability Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody CFZ533 in Kidney Transplant Recipients

The purpose of this study is to investigate the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of three CFZ533 dose regimens in kidney transplant recipients. This study will allow assessment of the ability of CFZ533 to replace Calcineurin inhibitors (CNIs) in terms of anti-rejection efficacy, while providing better renal function …

renal function
vaccination
tacrolimus
calcineurin inhibitor
kidney transplant
Novartis Investigative Site
 (7.3 away) Contact site
  • 31 views
  • 21 Oct, 2020
  • +85 other locations
Randomized Study to Evaluate Efficacy Safety and Tolerability of AMG 890 in Subjects With Elevated Lipoprotein(a)

Evaluate the effect of AMG 890 administered subcutaneously (SC) compared with placebo, on percent change from baseline in lipoprotein(a) (Lp[a]).

atherosclerotic cardiovascular disease
Research Site
 (7.3 away) Contact site
  • 0 views
  • 05 Nov, 2020
  • +20 other locations
RCT Cefiderocol vs BAT for Treatment of Gram Negative BSI

The purpose of this study is to determine whether a new antibiotic, Cefiderocol which works against a wide variety of gram negative bacteria, is equally effective as the antibiotics that are currently used as current standard of care.

Western Sydney Local Health District (Westmead Hospital)
 (7.3 away) Contact site
  • 88 views
  • 02 Dec, 2019
  • +11 other locations