North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 112 clinical trials
A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis

This is a Phase 2, multicenter, multinational, randomized, double-blind, placebo-controlled study evaluating the efficacy, safety, pharmacokinetics (PK), quality of life and exploratory pharmacodynamics (PD) of two treatment doses of CC-90001, 200 mg and 400 mg, compared with placebo, when delivered once daily per os (PO) in subjects with idiopathic pulmonary …

fibrosis
idiopathic pulmonary fibrosis
lung biopsy
forced vital capacity
diffusion capacity of the lung for carbon monoxide
Concord Repatriation General Hospital
 (4.8 away) Contact site
  • 1660 views
  • 06 Sep, 2020
  • +102 other locations
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

The purpose of this study is to collect long term safety data in subjects who are continuing to derive clinical benefit from treatment with Enzalutamide from the subjects participation in an enzalutamide clinical study sponsored by Astellas or Medivation (i.e., parent study) which has completed, at a minimum, the primary …

prednisone
antiandrogen therapy
androgen suppression
abiraterone
androgens
Site AU61004
 (7.7 away) Contact site
  • 1404 views
  • 05 Dec, 2020
  • +130 other locations
Evaluate F901318 Treatment of Invasive Fungal Infections in Patients Lacking Treatment Options

A study to evaluate F901318 (study drug) for the treatment of invasive fungal infections in patients lacking suitable alternative treatment options.

fungal infection
Westmead Hospital
 (7.9 away) Contact site
  • 291 views
  • 30 Jul, 2020
  • +38 other locations
Study of Safety and Efficacy of LNP023 in Patients With Kidney Disease Caused by Inflammation

Efficacy and safety of LNP023 in IgAN patients

antihypertensive drugs
h. influenzae
glomerular filtration rate
body mass index
adrenaline
Novartis Investigative Site
 (7.9 away) Contact site
  • 306 views
  • 27 Nov, 2020
  • +76 other locations
A Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination With Ruxolitinib in Participants With Myelofibrosis

This is a Phase 2 open-label, multicenter study evaluating tolerability and efficacy of navitoclax alone or when added to ruxolitinib in participants with myelofibrosis.

St. Vincent's Hospital, Darlinghurst /ID# 214657
 (8.2 away) Contact site
  • 251 views
  • 30 Nov, 2020
  • +81 other locations
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

Historically, medulloblastoma treatment has been determined by the amount of leftover disease present after surgery, also known as clinical risk (standard vs. high risk). Recent studies have shown that medulloblastoma is made up of distinct molecular subgroups which respond differently to treatment. This suggests that clinical risk alone is not …

brain tumor
tumor cells
corticosteroids
craniospinal irradiation
cancer
Children's Hospital at Westmead
 (7.9 away) Contact site
  • 144 views
  • 18 Oct, 2020
  • +24 other locations
A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors

This research study is done to test how well different types of cancer respond to the drug called larotrectinib. The cancer must have a change in a particular gene (NTRK1, NTRK2 or NTRK3). Larotrectinib is a drug that blocks the actions of these NTRK genes in cancer cells and can …

NTRK
measurable disease
cancer
Macquarie University Hospital
 (1.3 away) Contact site
  • 0 views
  • 26 Nov, 2020
  • +171 other locations
A Phase II Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma

This is a Phase II, multicenter, open-label, single arm, 2-stage study of tazemetostat 800 mg BID (twice daily) and 1600 mg QD (once daily). Subjects will be screened for eligibility within 21 days of the planned date of the first dose of tazemetostat and enrolled into one of 8 cohorts: …

synovial sarcoma
carcinoma
epithelioid sarcoma
measurable disease
nitrosoureas
Chris O'Brien Lifehouse
 (7.5 away) Contact site
  • 0 views
  • 28 Oct, 2020
  • +24 other locations
Effects of JNJ-53718678 in Adult and Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With Respiratory Syncytial Virus (RSV)

The purpose of this study is to evaluate the effect of JNJ-53718678 on the development of respiratory syncytial virus (RSV) lower respiratory tract infection (LRTIs) in adult hematopoietic stem cell transplant (HSCT) recipients with RSV upper RTI.

respiratory tract infection
respiratory symptom
conditioning regimen
cough
jnj-53718678
Westmead Hospital
 (7.7 away) Contact site
  • 49 views
  • 03 Dec, 2020
  • +165 other locations
Phase II Study to Assess AFM13 in Patients With R/R CD30-positive T-cell Lymphoma or Transformed Mycosis Fungoides

This is a phase II study to evaluate the antitumor activity and safety of AFM13 given as monotherapy in patients with CD30-positive T-cell lymphoma. The investigational medicinal product AFM13 is a tetravalent bispecific chimeric (anti-human CD30 x anti-human CD16A) recombinant antibody construct which is being developed to treat CD30-positive malignancies. …

mycosis fungoides
measurable disease
brentuximab vedotin
systemic therapy
avid
Concord Repatriation General Hospital
 (4.4 away) Contact site
  • 32 views
  • 29 Nov, 2020
  • +68 other locations