North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 112 clinical trials
Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study)

This is a phase II, open label, randomised trial of ipilimumab and nivolumab with concurrent intracranial stereotactic radiotherapy versus ipilimumab and nivolumab alone in patients with asymptomatic, untreated melanoma brain metastases.

Melanoma Institute Australia
 (5.0 away) Contact site
  • 16 views
  • 21 Sep, 2020
  • +5 other locations
Enzalutamide With Lu PSMA-617 Versus Enzalutamide Alone in Men With Metastatic Castration-resistant Prostate Cancer

This phase 2 randomised clinical trial will investigate the activity and safety of adding Lu-PSMA to enzalutamide in patients with metastatic castrate resistant prostate cancer (mCRPC) not previously treated with chemotherapy.

progressive disease
prostate adenocarcinoma
pet/ct
abiraterone
bone metastases
St Vincents Hospital
 (8.2 away) Contact site
  • 0 views
  • 08 Oct, 2020
  • +3 other locations
OLE Study for Patients With Parkinson's Disease With Dementia Enrolled in Study ANAVEX2-73-PDD-001

This is a Phase 2 open-label extension study to evaluate the effects of ANAVEX2-73 on safety and efficacy of daily treatment.

KaRa MINDS
 (0.8 away) Contact site
  • 0 views
  • 12 Oct, 2020
  • +4 other locations
A Study Assessing the Efficacy and Safety of CBP-201

This study will evaluate the efficacy, safety, pharmacokinetics and pharmacodynamics of CBP-201 in adult subjects with moderate to severe atopic dermatitis.

Connect Investigative Site 105
 (7.3 away) Contact site
  • 325 views
  • 11 Nov, 2020
  • +53 other locations
A Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)

This is a Phase 1b/2 dose-optimization study to evaluate safety, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of avelumab (MSB0010718C) in combination with other cancer immunotherapies in patients with locally advanced or metastatic solid tumors. The primary purpose is to assess the safety and early signs of efficacy of various avelumab …

gastric cancer
squamous cell carcinoma of head and neck
metastatic solid tumor
measurable disease
solid tumor
Macquarie University Hospital Pharmacy
 (1.3 away) Contact site
  • 193 views
  • 22 Nov, 2020
  • +113 other locations
This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia

The primary objective of this Phase II exploratory trial is to provide Proof of Concept (PoC) data to assess the effect on cognition of oral once daily administration of BI 425809 given for 12 weeks in patients with schizophrenia on stable antipsychotic treatment and adjunctive Computerized Cognitive Training (CCT).

anticholinergics
clozapine
antidepressants
cognitive training
antipsychotics
University of Sydney
 (7.3 away) Contact site
  • 773 views
  • 29 Nov, 2020
  • +54 other locations
A Study of Efficacy and Safety of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the clinical efficacy and safety of combination therapy with guselkumab and golimumab in participants with moderately to severely active ulcerative colitis (UC).

golimumab
Macquarie University Hospital
 (1.3 away) Contact site
  • 65 views
  • 03 Dec, 2020
  • +159 other locations
A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib (LY2835219) in Participants With Prostate Cancer

This study is being done to see how safe and effective abemaciclib is when given together with abiraterone acetate plus prednisone in participants with metastatic castration resistant prostate cancer. Prednisolone may be used instead of prednisone per local regulation.

adenocarcinoma of prostate
prostate cancer metastatic
metastatic prostate cancer
androgens
progressive disease
Macquarie University Hospital
 (1.3 away) Contact site
  • 501 views
  • 28 Nov, 2020
  • +122 other locations
Efficacy and Safety of TD-1473 in Crohn's Disease

A Phase 2 study to evaluate the efficacy, safety and tolerability of TD-1473 in subjects with moderately-to-severely active Crohn's Disease with up to 48 weeks of treatment.

anti-tnf therapy
aminosalicylate
corticosteroids
mercaptopurine
methotrexate
Theravance Biopharma Investigational Site
 (9.9 away) Contact site
  • 317 views
  • 04 Nov, 2020
  • +208 other locations
Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF-06700841 In Subjects With Moderate To Severe Crohn's Disease

The objectives of this study are to evaluate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06651600 (200 mg for 8 weeks followed by 50 mg for 4 weeks) dosed once daily and PF-06700841 (60 mg for 12 weeks) dosed once daily during an induction period of 12 weeks, followed …

corticosteroids
immunosuppressive agents
antibiotic therapy
mesalamine
conventional treatment
Concord Repatriation General Hospital
 (4.8 away) Contact site
  • 1357 views
  • 23 Nov, 2020
  • +278 other locations