North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 111 clinical trials
Osteonecrosis of the Hip and Bisphosphonate Treatment

Osteonecrosis of the hip is an important cause of musculoskeletal disability and finding therapeutic solutions has proven to be challenging. Osteonecrosis means death of bone which can occur from the loss of the blood supply or some other means. Although any age group may develop osteonecrosis, most patients are between …

steroid treatment
core decompression
zoledronic acid
Royal North Shore Hospital, Department of Rheumatology
 (5.0 away) Contact site
  • 07 Nov, 2020
  • +4 other locations
Pulsed Electromagnetic Field (PEMF) Stimulation for Tibia Fractures

Fractures of the tibial shaft (diaphysis) are some of the most common long bone fractures. They most frequently occur in males less than 40 years of age. Despite advancements in the surgical management of these fractures, the precarious blood supply and lack of soft-tissue cover of the shaft of the …

external fixation
multiple procedures
Westmead Hospital
 (9.9 away) Contact site
  • 07 Nov, 2020
  • +3 other locations
Micronised Resveratrol as a Treatment for Friedreich Ataxia

The aim of this study is to assess the efficacy of micronised resveratrol as a treatment for FRDA, in terms of reducing the severity of ataxia symptoms at 24 weeks, through a randomised blinded, placebo controlled crossover trial.

total bilirubin
Royal North Shore Hospital
 (4.8 away) Contact site
  • 10 Sep, 2020
  • +3 other locations
ASA in Prevention of Ovarian Cancer (STICs and STONEs)

While ASA is not a cancer medication, research suggests that taking ASA reduces the probability of getting many types of cancer because of its anti-inflammatory action. Inflammation in the ovaries during ovulation is thought to contribute to the development of ovarian cancer, and, because ASA is an anti-inflammatory medication, it …

Westmead Hospital
 (7.7 away) Contact site
  • 20 Jul, 2020
  • +19 other locations
International Multicentre Study in Advanced Anal Cancer Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Weekly Paclitaxel

Anal cancer is a relatively uncommon disease and there is currently no standard chemotherapy treatment for patients with inoperable locally recurrent or metastatic disease. The aim of this phase II study is compare two well known and largely used chemotherapy regimens - Cisplatin plus 5-fluorouracil vs Carboplatin plus Paclitaxel. The …

Margot Gorzeman
 (7.3 away) Contact site
  • 08 Nov, 2020
  • +1 other locations
A Study to Evaluate the Effectiveness and Safety of IONIS-FB-LRx an Antisense Inhibitor of Complement Factor B in Adult Participants With Primary IgA Nephropathy

The purpose of this study is to evaluate the effectiveness and safety of IONIS-FB-LRx, an antisense inhibitor of complement factor B messenger ribonucleic acid (CFB mRNA), and to evaluate the effect of IONIS-FB-LRx on plasma factor B (FB) levels and serum AH50, CH50 activity in participants with primary immunoglobulin A …

IONIS Investigative Site
 (4.8 away) Contact site
  • 09 Mar, 2020
  • +5 other locations
Non Small Cell Lung Cancer Trial of Durvalumab and Tremelimumab in Advanced Epidermal Growth Factor Receptor (EGFR) Mutant Disease.

The primary purpose of this trial is to evaluate the efficacy and tolerability of durvalumab and tremelimumab with platinum-pemetrexed in patients with metastatic NSCLC (T790+ve or T790M-ve) following progression on EGFR Tyrosine Kinase Inhibitors.. Study population: Individuals may be eligible to enrol in this trial if aged 18 or over …

Bankstown Hospital
 (9.9 away) Contact site
  • 08 Jul, 2020
  • +15 other locations
Enzalutamide With Lu PSMA-617 Versus Enzalutamide Alone in Men With Metastatic Castration-resistant Prostate Cancer

This phase 2 randomised clinical trial will investigate the activity and safety of adding Lu-PSMA to enzalutamide in patients with metastatic castrate resistant prostate cancer (mCRPC) not previously treated with chemotherapy.

conjugated bilirubin
progressive disease
renal function
St Vincents Hospital
 (8.2 away) Contact site
  • 08 Oct, 2020
  • +3 other locations
A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain Metastases

20-40% of patients with NSCLC will develop brain metastases at some point during their course of disease. Osimertinib has demonstrated intracranial activity in EFGR mutated NSCLC with leptomeningeal disease in the phase 1 BLOOM study. Stereotactic radiosurgery (SRS) is one of the standard local treatment for patients with limited number …

Liverpool Hospital
 (7.3 away) Contact site
  • 16 Nov, 2020
  • +12 other locations
Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM

This study aims to investigate effect of Nivolumab and Temozolomide vs Temozolomide alone on overall survival in newly diagnosed elderly patients with glioblastoma. Who is it for? You may be eligible to join this study if you are aged 65 years or above, with newly diagnosed histologically confirmed GBM (WHO …

renal function test
Royal North Shore Hospital
 (4.8 away) Contact site
  • 15 Dec, 2019
  • +15 other locations