North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 108 clinical trials
RCT Cefiderocol vs BAT for Treatment of Gram Negative BSI

The purpose of this study is to determine whether a new antibiotic, Cefiderocol which works against a wide variety of gram negative bacteria, is equally effective as the antibiotics that are currently used as current standard of care.

Western Sydney Local Health District (Westmead Hospital)
 (7.3 away) Contact site
  • 88 views
  • 02 Dec, 2019
  • +11 other locations
A Study of Erdafitinib in Participants With Advanced Solid Tumors and Fibroblast Growth Factor Receptor (FGFR) Gene Alterations

The purpose of this study is to evaluate the efficacy of erdafitinib in terms of overall response rate (ORR) in participants with advanced solid tumors with fibroblast growth factor receptor (FGFR) mutations and gene fusions.

measurable disease
growth factor
cancer
solid tumour
Chris O'Brien Lifehouse
 (7.3 away) Contact site
  • 33 views
  • 11 Nov, 2020
  • +253 other locations
A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adult Participants With Moderate to Severe Ulcerative Colitis

This phase 2b study is designed to have all subjects go into a 12 week induction period to compare different doses of study drug against placebo. After induction is complete all subjects will receive active therapy for 40 weeks, followed by a 12 week follow up period.

Concord Repatriation General Hospital
 (4.4 away) Contact site
  • 32 views
  • 11 Oct, 2020
  • +135 other locations
A Safety Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis

This is a phase 2 randomized, multi-center, double-blind, vehicle controlled, 12-week, safety, efficacy, and systemic exposure study followed by a 12-week open-label extension of trifarotene cream in adults and adolescents with autosomal recessive ichthyosis with lamellar scale

Premier Specialists Ptd Ltd
 (7.3 away) Contact site
  • 101 views
  • 22 Mar, 2020
  • +23 other locations
Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)

This study will evaluate the efficacy and safety of olaparib (MK-7339) monotherapy in participants with multiple types of advanced cancer (unresectable and/or metastatic) that: 1) have progressed or been intolerant to standard of care therapy; and 2) are positive for homologous recombination repair mutation (HRRm) or homologous recombination deficiency (HRD).

Kinghorn Cancer Centre ( Site 2200)
 (8.2 away) Contact site
  • 135 views
  • 23 Nov, 2020
  • +142 other locations
Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis

The objective of this study is to investigate the effect of K-321 in patients with Fuchs endothelial corneal dystrophy (FECD) after descemetorhexis.

corneal dystrophy
Sydney Eye Hospital
 (7.3 away) Contact site
  • 0 views
  • 25 Nov, 2020
  • +28 other locations
Pulsed Electromagnetic Field (PEMF) Stimulation for Tibia Fractures

Fractures of the tibial shaft (diaphysis) are some of the most common long bone fractures. They most frequently occur in males less than 40 years of age. Despite advancements in the surgical management of these fractures, the precarious blood supply and lack of soft-tissue cover of the shaft of the …

external fixation
multiple procedures
Westmead Hospital
 (9.9 away) Contact site
  • 105 views
  • 07 Nov, 2020
  • +3 other locations
Pembrolizumab With Chemoradiotherapy as Treatment for Muscle Invasive Bladder Cancer

This study will enrol patients with maximally resected (via transurethral resection (TURBT) non-metastatic muscle invasive bladder cancer, who either wish to attempt bladder preservation therapy or are ineligible for cystectomy. Patients must have adequate organ function and performance status to receive cisplatin based chemoradiotherapy, and no contraindications to the use …

pembrolizumab
carcinoma
direct bilirubin
neutrophil count
cystoscopy
Royal North Shore Hospital
 (4.8 away) Contact site
  • 39 views
  • 30 Jan, 2020
  • +6 other locations
ASA in Prevention of Ovarian Cancer (STICs and STONEs)

While ASA is not a cancer medication, research suggests that taking ASA reduces the probability of getting many types of cancer because of its anti-inflammatory action. Inflammation in the ovaries during ovulation is thought to contribute to the development of ovarian cancer, and, because ASA is an anti-inflammatory medication, it …

Westmead Hospital
 (7.7 away) Contact site
  • 375 views
  • 20 Jul, 2020
  • +19 other locations
In Men With Metastatic Prostate Cancer What is the Safety and Benefit of Lutetium-177 PSMA Radionuclide Treatment in Addition to Chemotherapy

This phase 2 randomised clinical trial will compare the effectiveness of Lu-PSMA therapy followed by docetaxel chemotherapy versus docetaxel chemotherapy on its own in patients with newly-diagnosed high-volume metastatic hormone-naive prostate cancer (mHNPC).

St Vincent's Hospital Sydney
 (8.2 away) Contact site
  • 0 views
  • 25 Nov, 2020
  • +3 other locations