North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 6 clinical trials
A Phase I Gene Therapy Study of FP253/Fludarabine for Prostate Cancer

The primary objective of this study is to determine the safety and tolerability of a gene-directed enzyme prodrug therapy for prostate cancer. FP253 contains an ovine atadenovirus that expresses the E. coli enzyme purine nucleoside phosphorylase (PNP) under the control of a prostate-directed promoter. PNP converts systemically administered fludarabine (the …

biopsy of prostate
bilateral orchidectomy
adenocarcinoma
gonadorelin
transrectal ultrasound
St Vincent's Hospital, Sydney
 (8.2 away) Contact site
  • 90 views
  • 07 Nov, 2020
  • 1 location
Idronoxil Suppository Combine With Radiotherapy for Metastatic Prostate Cancer

The aim of the study is to determine the toxicity of Idronoxil (NOX66) when used in combination with palliative radiotherapy for metastatic prostate cancer

Royal North Shore Hospital
 (4.8 away) Contact site
  • 42 views
  • 08 Nov, 2020
  • 1 location
177Lu-PSMA-617 Therapy and Olaparib in Patients With Metastatic Castration Resistant Prostate Cancer

This phase 1 dose-escalation and dose-expansion study is designed to evaluate the safety and tolerability of olaparib in combination with 177Lutetium-Prostate Specific Membrane Antigen (177 Lu-PSMA) in patients with metastatic castration resistant prostate cancer (mCRPC).

St Vincent's Hospital Sydney
 (7.3 away) Contact site
  • 14 views
  • 21 Jun, 2020
  • +1 other locations
Safety Tolerability Pharmacokinetics and Efficacy of AMG 160 in Subjects With mCRPC

A study to evaluate the safety and tolerability of AMG 160 and in combination with pembrolizumab in adult subjects with metastatic castration-resistant prostate cancer (mCRPC), and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

metastatic castration-resistant prostate cancer
bone scan
progressive disease
bilateral orchidectomy
gonadorelin
Research Site
 (7.5 away) Contact site
  • 217 views
  • 22 Nov, 2020
  • +16 other locations
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

metastatic castration-resistant prostate cancer
bone scan
progressive disease
bilateral orchidectomy
gonadorelin
Research Site
 (7.3 away) Contact site
  • 93 views
  • 27 Sep, 2020
  • +10 other locations
A Study to Establish the Feasibility of Biolen for the Local Delivery of Bicalutamide in Patients With Prostate Cancer

Biolen, a novel implant, is intended to deliver an anti-androgen locally to the prostate gland for the management of prostate disease, while minimizing systemic exposure and its associated side-effects. The objectives of the study are to assess whether the Biolen is safe.

prostatectomy
antiandrogen therapy
cancer
bicalutamide
androgens
Australian Clinical Trials
 (5.1 away) Contact site
  • 50 views
  • 12 Aug, 2020
  • +3 other locations