North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 45 clinical trials
The Zenflow Spring System EU Safety and Performance Study

The objectives of the trial are to demonstrate the safety and performance of the Zenflow Spring System in relieving the symptoms of obstructive Benign Prostatic Hyperplasia (BPH).

lower urinary tract symptoms
transrectal ultrasound
benign prostatic hypertrophy
total psa
free psa
Australian Clinical Trials
 (5.1 away) Contact site
  • 226 views
  • 05 Nov, 2019
  • +4 other locations
177Lu-PSMA-617 Therapy and Olaparib in Patients With Metastatic Castration Resistant Prostate Cancer

This phase 1 dose-escalation and dose-expansion study is designed to evaluate the safety and tolerability of olaparib in combination with 177Lutetium-Prostate Specific Membrane Antigen (177 Lu-PSMA) in patients with metastatic castration resistant prostate cancer (mCRPC).

St Vincent's Hospital Sydney
 (7.3 away) Contact site
  • 14 views
  • 21 Jun, 2020
  • +1 other locations
PRINCE (PSMA-lutetium Radionuclide Therapy and ImmuNotherapy in Prostate CancEr)

This investigator driven study will examine the safety, tolerability and efficacy of the combination of 177Lutetium-PSMA (177Lu-PSMA) and pembrolizumab in patients with metastatic Castration Resistant Prostate Cancer (mCRPC). 177Lu-PSMA is a compound that binds to the extra-cellular domain of the prostate-specific membrane antigen. Pembrolizumab is an antibody targeted against anti-programmed …

St Vincent's Hospital Sydney
 (7.3 away) Contact site
  • 63 views
  • 23 Sep, 2020
  • +3 other locations
Enzalutamide With Lu PSMA-617 Versus Enzalutamide Alone in Men With Metastatic Castration-resistant Prostate Cancer

This phase 2 randomised clinical trial will investigate the activity and safety of adding Lu-PSMA to enzalutamide in patients with metastatic castrate resistant prostate cancer (mCRPC) not previously treated with chemotherapy.

abiraterone
direct bilirubin
orchiectomy
adenocarcinoma
enzalutamide
St Vincents Hospital
 (8.2 away) Contact site
  • 0 views
  • 08 Oct, 2020
  • +3 other locations
In Men With Metastatic Prostate Cancer What is the Safety and Benefit of Lutetium-177 PSMA Radionuclide Treatment in Addition to Chemotherapy

This phase 2 randomised clinical trial will compare the effectiveness of Lu-PSMA therapy followed by docetaxel chemotherapy versus docetaxel chemotherapy on its own in patients with newly-diagnosed high-volume metastatic hormone-naive prostate cancer (mHNPC).

St Vincent's Hospital Sydney
 (8.2 away) Contact site
  • 0 views
  • 30 Nov, 2020
  • +4 other locations
Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC

This study compares rPFS in men with mCRPC treated with talazoparib plus enzalutamide vs. enzalutamide after confirmation of the starting dose of talazoparib in combination with enzalutamide.

Chris O'Brien Lifehouse
 (7.3 away) Contact site
  • 4293 views
  • 04 Nov, 2020
  • +477 other locations
A Study to Evaluate the Safety and Efficacy of Relugolix in Men With Advanced Prostate Cancer

The purpose of this study is to determine the efficacy and safety of relugolix 120 milligrams (mg) orally once daily for 48 weeks on maintaining serum testosterone suppression to castrate levels (< 50 nanograms/deciliter [ng/dL]) in participants with androgen-sensitive advanced prostate cancer.

adenocarcinoma
androgens
serum testosterone
prostatectomy
testosterone
Wahroonga
 (5.1 away) Contact site
  • 1590 views
  • 04 Nov, 2020
  • +351 other locations
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

The purpose of this study is to collect long term safety data in subjects who are continuing to derive clinical benefit from treatment with Enzalutamide from the subjects participation in an enzalutamide clinical study sponsored by Astellas or Medivation (i.e., parent study) which has completed, at a minimum, the primary …

androgen suppression
androgens
antiandrogen therapy
abiraterone
enzalutamide
Site AU61004
 (7.7 away) Contact site
  • 1404 views
  • 02 Dec, 2020
  • +130 other locations
Study to Assess the Efficacy of the iTind in Subjects With Symptomatic BPH

A total of up to 200 Symptomatic BPH subjects subjects will be enrolled into the study. Study duration will be 12 months post implantation with a follow-up visits at Year 2 and Year 3.

transrectal ultrasound
Sydney Adventist Hospital Clinical School of the University of Sydney
 (7.3 away) Contact site
  • 97 views
  • 10 Sep, 2020
  • +19 other locations
Study of SRP-4045 and SRP-4053 in DMD Patients

The main objective of this study is to evaluate the efficacy of SRP-4045 and SRP-4053 compared to placebo in Duchenne muscular dystrophy (DMD) patients with out-of-frame deletion mutations amenable to skipping exon 45 and exon 53, respectively.

deletion mutation
corticosteroids
forced vital capacity
muscular dystrophy
Children's Hospital at Westmead
 (7.7 away) Contact site
  • 0 views
  • 15 Jul, 2020
  • +73 other locations