North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 17 clinical trials
EXamining PErsonalised Radiation Therapy for Low-risk Early Breast Cancer

This is a randomised, phase III, non-inferiority trial evaluating radiation therapy versus observation following breast conserving surgery and planned endocrine therapy in patients with stage I breast cancer of luminal A subtype defined using the Prosigna (PAM50) Assay.

Mater Hospital Sydney
 (5.9 away) Contact site
  • 31 Aug, 2020
  • +46 other locations
Safety Tolerability and Efficacy of the Human Cytomegalovirus Vaccine (V160) in Healthy Women 16 to 35 Years of Age (V160-002)

This study will evaluate the safety, tolerability, and efficacy of Human Cytomegalovirus (CMV) vaccine V160 administered in a 2-dose or 3-dose regimen in healthy seronegative women 16 to 35 years of age. Participants will receive blinded V160 on Day 1, Month 2, and Month 6 (3-dose regimen), V160 on Day …

Holdsworth House Medical Practice ( Site 0241)
 (8.2 away) Contact site
  • 12 Aug, 2019
  • +95 other locations
POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer

POSNOC is a pragmatic, randomised, multicentre, non-inferiority trial. Aim For women with early stage breast cancer and one or two sentinel node macrometastases, to assess whether adjuvant therapy alone is no worse than adjuvant therapy plus axillary treatment, in terms of axillary recurrence within 5 years. Stratification: Institution, Age (<50, …

breast-conserving surgery
sentinel lymph node biopsy
endocrine therapy
estrogen receptor
Bankstown-Lidcocombe Hospital
 (9.9 away) Contact site
  • 12 Apr, 2020
  • +49 other locations
Use of Hair to Diagnose Breast Cancer

Study FT3.6k-2006 is a single centre (the Mater Hospital, Sydney), blinded trial of a diagnostic test for breast cancer, with outcomes compared to the gold standard of screening mammogram followed by biopsy where required. This study aims to perform X-ray diffraction analysis of coded hair samples from women with a …

breast cancer
The Mater Hospital
 (5.0 away) Contact site
  • 07 Nov, 2020
  • 1 location
ASA in Prevention of Ovarian Cancer (STICs and STONEs)

While ASA is not a cancer medication, research suggests that taking ASA reduces the probability of getting many types of cancer because of its anti-inflammatory action. Inflammation in the ovaries during ovulation is thought to contribute to the development of ovarian cancer, and, because ASA is an anti-inflammatory medication, it …

Westmead Hospital
 (7.7 away) Contact site
  • 20 Jul, 2020
  • +19 other locations
Breast Radiotherapy Audio Visual Enhancement for Sparing the Heart

This study investigates the Breathe Well device to test whether it is superior to the existing treatment standard of the Varian Realtime Position Management (RPM) system in assisting patients with deep inspiration breath hold.

Gillian Lamoury
 (4.8 away) Contact site
  • 08 Nov, 2020
  • 1 location
ANAVEX2-73 Study in Pediatric Patients With Rett Syndrome

ANAVEX2-73 Study in Pediatric Patients With Rett Syndrome: ANAVEX2-73-RS-003 is a Phase 2/3, double-blind, randomized, placebo-controlled dose escalation safety, tolerability and efficacy study in patients 5-18 years of age with RTT using endpoints including multiple clinical and exploratory molecular and biochemical measures.

treatment regimen
pregnancy testing
The Children's Hospital at Westmead
 (9.9 away) Contact site
  • 09 Jul, 2020
  • +1 other locations
Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients

ICON 9 will assess the efficacy, safety and tolerability of maintenance olaparib in combination with cediranib compared to maintenance olaparib alone following a response to platinum-based chemotherapy in women with relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer. Prognostic and predictive factors will be studied from tumour and blood samples.

endometrioid carcinoma
ovarian epithelial carcinoma
Calvary Mater Hospital
 (7.3 away) Contact site
  • 16 Sep, 2020
  • +40 other locations
Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Versus Chemotherapy for Endometrial Carcinoma (ENGOT-en9 / MK-7902-001)

The purpose of this study is to compare the efficacy of pembrolizumab + lenvatinib to chemotherapy in female participants with Stage III, IV, or recurrent endometrial carcinoma. It is hypothesized that the combination of pembrolizumab + lenvatinib will be superior to chemotherapy for progression-free survival (PFS) per Response Evaluation Criteria …

recurrent endometrial cancer
endometrial carcinoma
Royal North Shore Hospital ( Site 1600)
 (4.8 away) Contact site
  • 23 Nov, 2020
  • +211 other locations
Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical Cancer

The main purpose of this study is to evaluate clinical efficacy and safety of bintrafusp alfa in participants with advanced, unresectable cervical cancer with disease progression during or after platinum-containing chemotherapy.

Westmead Hospital
 (7.7 away) Contact site
  • 14 Oct, 2020
  • +81 other locations