North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 453 clinical trials
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A Study to Evaluate the Safety and Tolerability of ABBV-951 in Subjects With Parkinson's Disease (PD)

The purpose of this study is to assess the safety and tolerability of ABBV-951 in subjects with Parkinson's disease (PD).

levodopa
Concord Repatriation & Gen Hos /ID# 207628
 (4.4 away) Contact site
  • 395 views
  • 18 May, 2020
  • +20 other locations
Treatment of Invasively Ventilated Adults With Early Activity and Mobilisation

The aim of this study is to evaluate the effect of early activity and mobilisation during prolonged IMV on the composite outcome "days alive and out of hospital to day 180". The effect of the intervention on mortality, physical, cognitive and Psychological function at 180 days, as well as cost-effectiveness …

Royal Prince Alfred Hospital
 (7.5 away) Contact site
  • 1116 views
  • 08 Nov, 2020
  • +20 other locations
A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity

This is an open-label, multi-institutional phase II randomized study comparing neoadjuvant radiotherapy followed by surgical resection to neoadjuvant pembrolizumab with concurrent radiotherapy, followed by surgical resection and adjuvant pembrolizumab. The total duration of pembrolizumab will be one year in the experimental arm.

Chris O'Brien Hospital
 (7.5 away) Contact site
  • 56 views
  • 27 Jan, 2020
  • +16 other locations
Study to Assess Safety Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors

The primary objective of this study is to determine the safety and tolerability of pamiparib, the maximum tolerated dose (MTD) or maximum administered dose (MAD) for pamiparib combined with TMZ, to select the recommended Phase 2 dose (RP2D) and schedule of pamiparib in combination with TMZ, and to determine the …

Chris O'Brien Lifehouse
 (7.5 away) Contact site
  • 28 views
  • 21 Sep, 2020
  • +20 other locations
Safety Pharmacokinetics (PK) and Efficacy of MK-1308 in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)

This study will assess the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of escalating doses of MK-1308 when used in combination with pembrolizumab in participants with advanced solid tumors.

Melanoma Institute Australia ( Site 0017)
 (5.0 away) Contact site
  • 742 views
  • 28 Oct, 2020
  • +45 other locations
Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Young Children 1-3 Years of Age

The study aims to assess the safety and efficacy of Viaskin Peanut to induce desensitization to peanut in peanut-allergic children 1 to 3 years of age after a 12-month treatment by EPicutaneous ImmunoTherapy (EPIT).

a 12
The Children's Hospital at Westmead
 (7.7 away) Contact site
  • 246 views
  • 01 Nov, 2020
  • +50 other locations
Thin Wire Versus Thick Wire Snare for Cold Snare Polypectomy of Diminutive Polyps

Cold snare polypectomy (CSP) is now common practice and has proven to be a safe and effective technique for removal of diminutive polyps. Both thick and thin wire snares are now commonly used for CSP. However, because of their physical characteristics, thick wire snares might leave a higher percentage of …

polypectomy
adenoma
endoscopy
cancer
Auburn Hosptial
 (6.4 away) Contact site
  • 50 views
  • 08 Jul, 2019
  • 1 location
MOre REsponse on Cardiac Resynchronization Therapy With MultiPoint Pacing

The purpose of this Clinical investigation is to assess the impact of the Multi Point Pacing (MPP) feature at 12 months in the treatment of patients not responding to standard Cardiac Resynchronization Therapy (CRT) after 6 months.

cardiac resynchronization therapy
Westmead Hospital
 (7.9 away) Contact site
  • 1090 views
  • 01 Dec, 2019
  • +223 other locations
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require …

Concord Repatriation General Hospital
 (4.8 away) Contact site
  • 41 views
  • 05 Nov, 2020
  • +97 other locations
Letermovir Versus Valganciclovir to Prevent Human Cytomegalovirus Disease in Kidney Transplant Recipients (MK-8228-002)

The primary objective of this study is to evaluate the efficacy of letermovir (LET) versus valganciclovir (VGCV) in preventing CMV disease in adult kidney transplant recipients. The primary hypotheses are that LET is non-inferior to VGCV; and if non-inferiority is demonstrated, that LET is superior to VGCV, in preventing CMV …

Royal Prince Alfred Hospital ( Site 0005)
 (7.5 away) Contact site
  • 177 views
  • 21 Nov, 2020
  • +97 other locations