North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 67 clinical trials
AMG 404 in Patients With Advanced Solid Tumors.

To evaluate the safety and tolerability of AMG 404, a monoclonal antibody that binds to PD-1 and inhibits its engagement with ligands, in patients with advanced solid tumors.

Research Site
 (7.3 away) Contact site
  • 87 views
  • 02 Dec, 2020
  • +16 other locations
Study to Determine the Safety Tolerability Pharmacokinetics and RP2D of ABBV-151 as a Single Agent and in Combination With ABBV-181 in Participants With Locally Advanced or Metastatic Solid Tumors

The study will determine the recommended Phase 2 dose (RP2D) of ABBV-151 administered as monotherapy and in combination with ABBV-181 as well as to assess the safety, pharmacokinetics (PK), and preliminary efficacy of ABBV-151 alone and in combination with ABBV-181. The study will consist of 2 phases: dose escalation and …

Chris O'Brien Lifehouse /ID# 213236
 (7.6 away) Contact site
  • 17 views
  • 14 Jun, 2020
  • +20 other locations
Study Evaluating Safety Tolerability and PK of AMG 757 in Adults With Small Cell Lung Cancer

A study to assess the safety, tolerability, and pharmacokinetics of AMG 757 in Subjects with Small Cell Lung Cancer

brain metastases
metastasis
pembrolizumab
Research Site
 (7.5 away) Contact site
  • 398 views
  • 04 Nov, 2020
  • +26 other locations
A Study of ZN-c5 in Participants With Breast Cancer

This is a Phase 1 open-label, multicenter study to evaluate biomarkers for ZN-c5 in subjects with breast cancer

estradiol
breast adenocarcinoma
Site 9
 (1.3 away) Contact site
  • 37 views
  • 05 Nov, 2020
  • +16 other locations
A Study of SHR-A1811 in Subjects With Advanced Malignant Solid Tumors

This is an open-label, two-part study to evaluate the safety, tolerability, pharmacokinetics and immunogenicity of SHR-A1811 and preliminary anti-tumor efficacy in HER2 expressing or mutated advanced malignant solid tumor subjects.

Macquarie University Hospital
 (1.3 away) Contact site
  • 0 views
  • 18 Nov, 2020
  • +10 other locations
A Phase 1 Study of HLX20 a Human Monoclonal Antibody Targeting PD-L1Protein in Patients With Advanced Solid Tumors

This is an open-label, dose escalation, first-in-human study of HLX20, an anti-PD-L1 monoclonal antibody, in patients with metastatic or recurrent solid tumors who have failed standard therapy.

Kinghorn cancer centre
 (8.2 away) Contact site
  • 47 views
  • 08 Nov, 2020
  • +1 other locations
A Study Evaluating the Safety Tolerance and Anti-tumor Activity of a Study Drug in Subjects With Advanced Solid Tumors

This is a study to evaluate the safety and tolerability of the study drug HBM4003, and to determine the maximum tolerated dose and/or recommended Phase 2 study dose of HBM4003. Participants will receive 3 escalating doses of HBM4003, with the possibility of a fourth, higher dose level following review by …

serum pregnancy test
solid tumour
Macquarie University, 2 Technology Place
 (1.3 away) Contact site
  • 4 views
  • 20 Jan, 2020
  • +1 other locations
A Study of CS3002 in Subjects With Advanced Solid Tumors

This is a phase I, open-label, multiple-dose, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics and anti-tumor activity of CS3002 in subjects with advanced solid tumors.

blood transfusion
serum pregnancy test
hysterectomy
solid tumour
measurable disease
Chris O'Brien Lifehouse
 (7.3 away) Contact site
  • 3 views
  • 16 Mar, 2020
  • +1 other locations
FPT155 in Patients With Advanced Solid Tumors

This study is a Phase 1 open-label, first-in-human, multicenter study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and activity of FPT155 as monotherapy in patients with advanced solid tumors.

Chris O'Brien Lifehouse
 (7.3 away) Contact site
  • 7 views
  • 07 May, 2020
  • +11 other locations
Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

The purpose of this study is to evaluate whether DB-020 administered via an injection in the middle ear prevents hearing loss in participants who will receive high doses of cisplatin as part of their treatment for cancer.

The Crown Princess Mary Cancer Care Centre
 (7.7 away) Contact site
  • 0 views
  • 26 Jul, 2020
  • +10 other locations