North Ryde, Australia Clinical Trials

A listing of North Ryde, Australia clinical trials actively recruiting patients volunteers.

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Found 505 clinical trials
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require …

Concord Repatriation General Hospital
 (4.8 away) Contact site
  • 41 views
  • 05 Nov, 2020
  • +97 other locations
Letermovir Versus Valganciclovir to Prevent Human Cytomegalovirus Disease in Kidney Transplant Recipients (MK-8228-002)

The primary objective of this study is to evaluate the efficacy of letermovir (LET) versus valganciclovir (VGCV) in preventing CMV disease in adult kidney transplant recipients. The primary hypotheses are that LET is non-inferior to VGCV; and if non-inferiority is demonstrated, that LET is superior to VGCV, in preventing CMV …

Royal Prince Alfred Hospital ( Site 0005)
 (7.5 away) Contact site
  • 177 views
  • 21 Nov, 2020
  • +97 other locations
Phase ll Study of Pirfenidone in Patients With RAILD (TRAIL1)

The purpose of this study is to to assess the safety and tolerability of pirfenidone 2403 mg/day for the treatment of RA-associated interstitial lung disease.

Royal Prince Alfred Hospital
 (7.5 away) Contact site
  • 207 views
  • 08 Jul, 2019
  • +30 other locations
Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers

We hypothesize through this randomized, placebo-controlled adjuvant study, that Aspirin in patients with dukes C or high risk dukes B colorectal cancer (ASCOLT) can improve survival in this patient population over placebo control. If indeed found to be beneficial, because aspirin is cheap and easy to administer, it will positively …

aspirin
colon cancer
PIK3CA
rectal carcinoma
Northern Cancer Institute, St Leonards
 (4.8 away) Contact site
  • 646 views
  • 07 Nov, 2020
  • +42 other locations
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)

This is a prospective, multicenter, open-label, randomized, controlled, parallel group, group-sequential, event-driven Phase 3 study to evaluate efficacy, safety and pharmacokinetics (PK) of macitentan in children.

hypertension
connective tissue disease
macitentan
heart disease
Children's Hospital at Westmead
 (7.7 away) Contact site
  • 172 views
  • 29 Nov, 2020
  • +104 other locations
A Study of Bendamustine and Rituximab Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated Mantle Cell Lymphoma

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

cyclin d1
acalabrutinib
bendamustine
rituximab
Research Site
 (4.8 away) Contact site
  • 1270 views
  • 30 Jul, 2020
  • +212 other locations
Comparison of VT Ablation Outcomes Using Remote MAGNETIC Navigation Versus Manual Approach in a Low LVEF Population

The study purpose is to demonstrate that ventricular tachycardia (VT) ablation using the Niobe ES system results in superior outcomes compared to a manual approach in subjects with ischemic scar VT in a low ejection fraction population.

infarct
scar
myocardial infarction
catheter ablation
ejection fraction
Westmead Hospital
 (7.9 away) Contact site
  • 0 views
  • 23 Mar, 2020
  • +15 other locations
Plasma-Lyte 148 versUs Saline Study

The aim of PLUS is to conduct a multi-centre, blinded, randomised, controlled trial (RCT) to determine whether fluid resuscitation and therapy with a "balanced" crystalloid solution (Plasma-Lyte 148) decreases 90-day mortality in critically ill patients requiring fluid resuscitation when compared with the same treatment using 0.9% sodium chloride (saline)

Concord Repatriation General Hospital
 (3.5 away) Contact site
  • 0 views
  • 04 Oct, 2020
  • +52 other locations
Study of REGN2810 in Patients With Advanced Cutaneous Squamous Cell Carcinoma

For Groups 1 to 4, the primary objective of this study is to estimate the clinical benefit of cemiplimab monotherapy for patients with: metastatic (nodal or distant) cutaneous squamous cell carcinoma (CSCC), or unresectable locally advanced CSCC. For Group 6, the primary objective is to provide additional efficacy and safety …

Royal North Shore Hospital
 (4.8 away) Contact site
  • 0 views
  • 17 Nov, 2020
  • +100 other locations
A Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

The purpose of the study is to compare the safety and efficacy of Tafasitamab with BEN versus RTX with BEN in adult patients with relapsed of refractory DLBCL.

diffuse large b-cell lymphoma refractory
marginal zone lymphoma
measurable disease
bendamustine
rituximab
MorphoSys Research Site
 (4.8 away) Contact site
  • 0 views
  • 22 Mar, 2020
  • +152 other locations