Essendon, Australia Clinical Trials

A listing of Essendon, Australia clinical trials actively recruiting patients volunteers.

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Found 235 clinical trials
A Study of Abemaciclib (LY2835219) Plus Hormone Therapy in Participants With Early Breast Cancer

The main purpose of this study is to measure how well abemaciclib works in participants with early breast cancer who are taking hormone therapy after surgery. Participants must have breast cancer that is hormone receptor positive (HR+) and human epidermal receptor 2 positive (HER2+). Your participation could last up to …

hormone therapy
trastuzumab
pertuzumab
erbb2
invasive breast cancer
Peter MacCallum Cancer Centre
 (5.2 away) Contact site
  • 0 views
  • 17 Jun, 2021
  • +503 other locations
Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: The VAPOR-C Trial

VAPOR-C is a randomised study of the impact of IV versus inhaled anaesthesia (propofol versus sevoflurane) and lidocaine versus placebo on duration of disease free survival inpatients with either colorectal or non small cell lung cancer.

lung carcinoma
Footscray Hospital
 (3.5 away) Contact site
  • 0 views
  • 18 Jun, 2021
  • +13 other locations
Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC

This study compares rPFS in men with mCRPC treated with talazoparib plus enzalutamide vs. enzalutamide after confirmation of the starting dose of talazoparib in combination with enzalutamide.

Pharmacy Services, Peter MacCallum Cancer Centre
 (3.8 away) Contact site
  • 4293 views
  • 27 May, 2021
  • +497 other locations
Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy

The purpose of this study is to determine the clinical benefit and characterize the safety profile of tabelecleucel for the treatment of Epstein-Barr virus-associated post-transplant lymphoproliferative disease (EBV+ PTLD) in the setting of (1) solid organ transplant (SOT) after failure of rituximab and rituximab plus chemotherapy or (2) allogeneic hematopoietic …

chemotherapy regimen
myeloid malignancy
ct scan
remission
cancer
The Royal Children's Hospital Melbourne (Pediatrics only)
 (3.2 away) Contact site
  • 70 views
  • 23 May, 2021
  • +76 other locations
A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL

To compare efficacy between zanubrutinib versus bendamustine and rituximab in patients with previously untreated CLL/SLL, as measured by progression free survival.

chemoimmunotherapy
cyclophosphamide
fludarabine
rituximab
bendamustine
Saint Vincent's Hospital Melbourne
 (5.1 away) Contact site
  • 1222 views
  • 08 May, 2021
  • +242 other locations
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial

An investigator initiated and conducted, multicentre, international, double-blinded, placebo-controlled, parallel-group, randomised controlled trial, to determine the effects of a fixed low-dose combination blood pressure lowering pill ("Triple Pill") on top of standard of care on blood pressure control, and on time to first occurrence of recurrent stroke, in patients with …

stroke
telmisartan
amlodipine
systolic blood pressure
Royal Melbourne Hospital
 (4.2 away) Contact site
  • 399 views
  • 25 Jan, 2021
  • +85 other locations
Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients

The purpose of the study is to evaluate efficacy and safety of Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-Edotreotide compared to targeted molecular therapy with Everolimus in patients with inoperable, progressive, somatostatin receptor-positive (SSTR+), neuroendocrine tumours of gastroenteric or pancreatic origin (GEP-NET).

edotreotide
somatostatin
radionuclide therapy
measurable disease
progressive disease
Peter MacCallum Cancer Centre
 (5.4 away) Contact site
  • 220 views
  • 19 Apr, 2021
  • +82 other locations
Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)

This Phase 3 multinational, randomized, double-blind study is designed to compare the efficacy and safety of the combination of ibrutinib and venetoclax vs. ibrutinib and placebo in subjects with MCL.

ibrutinib
cyclin d1
renal function tests
venetoclax
TP53
St.Vincent's Hospital
 (5.0 away) Contact site
  • 908 views
  • 06 Mar, 2021
  • +179 other locations
A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis Post Polycythemia Vera Myelofibrosis or Post-Essential Thrombocythemia Myelofibrosis

This study (study ID PAC203 North America; PAC303 ex-North America) is evaluating 200 mg BID of pacritinib compared to physician's choice (P/C) therapy in patients with MF and severe thrombocytopenia (platelet count <50,000/L). Approximately 348 patients in total will be enrolled, randomized 2:1 to either pacritinib (approximately 232 patients) or …

blood blast count
blast cells
thrombocytosis
thrombocythemia
pacritinib
Alfred Hospital, Malignant Hematology and Stem Cell Transplantation Service
 (5.2 away) Contact site
  • 506 views
  • 15 Jun, 2021
  • +175 other locations
Efficacy and Safety of FG-4592 for Treatment of Anemia in Patients With Lower Risk MDS With Low Red Blood Cell Transfusion Burden

The purpose of this study is to determine whether FG-4592 is safe and effective in the treatment of anemia in patients with Lower Risk Myelodysplastic Syndrome and Low Red Blood Cell Transfusion Burden.

Investigational Site
 (7.7 away) Contact site
  • 44 views
  • 17 Feb, 2021
  • +74 other locations