Essendon, Australia Clinical Trials

A listing of Essendon, Australia clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 235 clinical trials
A Phase 3 Multi-Center Randomized Double-Blind Placebo-Controlled Study of Fostamatinib Disodium in the Treatment of wAIHA

The primary objective of this study is to assess the efficacy of fostamatinib in subjects with warm antibody autoimmune hemolytic anemia (wAIHA).

The Alfred Hospital
 (6.7 away) Contact site
  • 113 views
  • 12 Jun, 2021
  • +124 other locations
A Study to Evaluate the Safety Tolerability and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS) and to assess the pharmacokinetics (PK) of BIIB017 in pediatric participants with RRMS in Part 1. In Part 2, the study will evaluate the long-term safety of BIIB017 and further …

relapsing multiple sclerosis
magnetic resonance imaging brain
interferon
Research Site
 (3.2 away) Contact site
  • 109 views
  • 02 Apr, 2021
  • +69 other locations
Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)

Combination therapy in pulmonary arterial hypertension (PAH) has been the subject of active investigation for more than a decade, with the benefit of targeting different pathways known to be involved in the pathogenesis of the disease. Adherence to prescribed therapy has an impact on clinical outcomes. Reducing the pill/tablet count …

St. Vincent's Hospital Melbourne
 (5.0 away) Contact site
  • 100 views
  • 16 Jun, 2021
  • +218 other locations
Adalimumab vs. Conventional Immunosuppression for Uveitis Trial

Non-infectious intermediate, posterior, and panuveitides are chronic, potentially-blinding diseases. Vision-threatening cases require long-term therapy with oral corticosteroids and immunosuppression. Based upon preliminary data, adalimumab, a fully-human, anti-TNFmonoclonal antibody, now US FDA-approved for uveitis treatment, may be a superior corticosteroid-sparing agent than conventional immunosuppressive drugs. The ADVISE Trial is multicenter randomized, …

monoclonal antibodies
corticosteroids
cyclosporine
adalimumab
panuveitis
Centre for Eye Research Australia
 (5.9 away) Contact site
  • 103 views
  • 24 Jan, 2021
  • +26 other locations
Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients in this study will have …

enfortumab vedotin
pd-l1
metastatic urothelial carcinoma
pembrolizumab
adjuvant chemotherapy
Site AUS61004
 (8.6 away) Contact site
  • 5 views
  • 27 May, 2021
  • +76 other locations
Efficacy and Safety of Odevixibat in Children With Biliary Atresia Who Have Undergone a Kasai HPE (BOLD)

Double-blind, randomized, placebo-controlled, Phase 3 study to investigate the efficacy and safety of odevixibat compared to placebo in children with biliary atresia who have undergone a Kasai hepatoportoenterostomy.

Royal Children's Hospital
 (3.2 away) Contact site
  • 0 views
  • 14 Jun, 2021
  • +50 other locations
Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion

Patients presenting to the emergency department with an acute ischemic stroke due to a large vessel occlusion eligible for thrombectomy and target mismatch on computed tomography perfusion imaging within 24 hours of onset will be assessed determine their eligibility for randomization into the trial. If the patient gives informed consent …

alteplase
stenosis
stroke
plasminogen
thrombectomy
Royal Melbourne Hospital
 (4.2 away) Contact site
  • 0 views
  • 26 Jan, 2021
  • +3 other locations
Study of Capmatinib Efficacy in Comparison With Docetaxel in Previously Treated Participants With Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation

The purpose of the study is to learn whether the study drug (capmatinib) helps to control lung cancer better compared to a single agent chemotherapy (docetaxel) and whether it is safe when given to patients suffering from a particular type of lung cancer. This type of cancer is called non-small …

growth factor
lung carcinoma
epidermal growth factor receptor
docetaxel
cancer chemotherapy
Novartis Investigative Site
 (5.4 away) Contact site
  • 0 views
  • 13 Jun, 2021
  • +42 other locations
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

growth factor
osimertinib
lung carcinoma
epidermal growth factor receptor
stage iv non-small cell lung cancer
Austin Hospital
 (8.6 away) Contact site
  • 27 views
  • 02 Jun, 2021
  • +307 other locations
Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC)

This is a Phase III, randomized, parallel-arm, placebo controlled, double blind, multicenter study assessing the efficacy and safety of durvalumab versus placebo following SoC chemotherapy in patients with completely resected stage II-III NSCLC who are MRD+ post surgery

lung carcinoma
cancer chemotherapy
durvalumab
Research Site
 (5.4 away) Contact site
  • 102 views
  • 02 Jun, 2021
  • +241 other locations