Essendon, Australia Clinical Trials

A listing of Essendon, Australia clinical trials actively recruiting patients volunteers.

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Found 9 clinical trials
Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients

ICON 9 will assess the efficacy, safety and tolerability of maintenance olaparib in combination with cediranib compared to maintenance olaparib alone following a response to platinum-based chemotherapy in women with relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer. Prognostic and predictive factors will be studied from tumour and blood samples.

platinum-based chemotherapy
fallopian tube
olaparib
metastasis
ovarian epithelial carcinoma
Peter MacCallum Cancer Centre
 (5.2 away) Contact site
  • 392 views
  • 10 Jun, 2021
  • +44 other locations
Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

The purpose of this study is to assess the efficacy and safety of treatment with carboplatin/paclitaxel* PLUS pembrolizumab (MK-3475) and maintenance olaparib (MK-7339) in women with epithelial ovarian cancer (EOC), fallopian tube cancer, or primary peritoneal cancer. The primary study hypotheses are that the combination of pembrolizumab plus carboplatin/paclitaxel* followed …

BRCA1
fallopian tube cancer
excisional biopsy
solid tumour
fallopian tube
Sunshine Hospital. ( Site 2205)
 (6.1 away) Contact site
  • 732 views
  • 09 Jun, 2021
  • +258 other locations
Neoadjuvant Hormonal Therapy Plus Palbociclib in Operable Hormone Sensitive and HER2-Negative Primary Breast Cancer

The study is a randomized, double blind, placebo controlled, Phase 3 clinical trial with the primary objective of demonstrating the efficacy of palbociclib in combination with Endocrine therapy over Endocrine therapy alone measured by PEPI and EndoPredict EPclin Score in women with operable HR+, HER2 negative breast cancer . The …

breast cancer
neutrophil count
her-2
cancer
hormone therapy
Peter MacCallum Cancer Centre
 (5.2 away) Contact site
  • 43 views
  • 30 May, 2021
  • +26 other locations
A Study of Mirvetuximab Soravtansine vs. Investigator's Choice of Chemotherapy in Platinum-Resistant Advanced High-Grade Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression

This Phase 3 study is designed to compare the efficacy and safety of mirvetuximab soravtansine vs. investigator's choice chemotherapy in patients with platinum-resistant high-grade epithelial ovarian cancer, primary peritoneal, or fallopian tube cancer, whose tumors express a high-level of FR. Patients will be, in the opinion of the Investigator, appropriate …

fallopian tube cancer
paclitaxel
mirvetuximab soravtansine
cancer
plat
Oncology Clinics Victoria (OCV) - Cabrini Malvern Hospital Location
 (10.0 away) Contact site
  • 88 views
  • 30 May, 2021
  • +145 other locations
Prospective Randomized Clinical Trial of Fetal Atrial Flutter & Supraventricular Tachycardia Therapy (FAST RCT)

Few studies are specifically designed to address health concerns relevant during pregnancy. The consequence is a lack of evidence on best clinical practice. This includes mothers and their babies when pregnancy is complicated by an abnormally fast heart rate up to 300 beats per minute due to supraventricular tachyarrhythmia (SVA) …

The Royal Women's Hospital
 (5.2 away) Contact site
  • 317 views
  • 25 Jan, 2021
  • +42 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

durvalumab
sarcoma
measurable disease
recurrent endometrial cancer
carcinoma
Research Site
 (5.4 away) Contact site
  • 104 views
  • 15 May, 2021
  • +192 other locations
Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047)

The purpose of this study is to evaluate the efficacy and safety of pembrolizumab plus concurrent chemoradiotherapy compared to placebo plus concurrent chemoradiotherapy in participants with locally advanced cervical cancer. The primary hypotheses are that pembrolizumab plus concurrent chemoradiotherapy is superior to placebo plus concurrent chemoradiotherapy with respect to progression-free …

chemoradiotherapy
external beam radiation therapy
brachytherapy
cancer
pembrolizumab
Peter MacCallum Cancer Centre ( Site 0971)
 (5.4 away) Contact site
  • 85 views
  • 11 Jun, 2021
  • +154 other locations
Sentinel Node Biopsy in Endometrial Cancer

Endometrial cancer (EC) is the most common gynaecological cancer. Current treatment of EC typically includes removal of the uterus and to determine the extent of the disease (removal of fallopian tubes, ovaries & if required a lymph node dissection (surgical staging)). While lymph node dissection may be valuable to guide …

Royal Women's Hospital
 (3.2 away) Contact site
  • 0 views
  • 01 Feb, 2021
  • +9 other locations
A Phase III Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine in Pregnant Women and Infants Born to Vaccinated Mothers

The purpose of this study is to evaluate the ability of a single dose of the investigational RSV Maternal vaccine, administered intramuscularly to pregnant women aged 18-49 years, in good general maternal health, in preventing medically assessed RSV associated Lower Respiratory Tract Illnesses (LRTIs) in infants born to vaccinated mothers. …

GSK Investigational Site
 (6.7 away) Contact site
  • 0 views
  • 13 May, 2021
  • +93 other locations