Douglas, Australia Clinical Trials

A listing of Douglas, Australia clinical trials actively recruiting patients volunteers.

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Found 23 clinical trials
Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile Infection

Summit is developing ridinilazole as a novel antimicrobial for Clostridium difficile Infection (CDI) with the goal of achieving comparable cure rates to standard of care, but reducing rates of recurrent disease. A phase 2 proof of concept study, with vancomycin as comparator, demonstrated these attributes with a comparable safety profile. …

clostridium difficile
antibiotic therapy
antibiotics
vancomycin
ridinilazole
Sunshine Coast University Hospital
 (650.3 away) Contact site
  • 101 views
  • 08 Jul, 2020
  • +223 other locations
Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers

We hypothesize through this randomized, placebo-controlled adjuvant study, that Aspirin in patients with dukes C or high risk dukes B colorectal cancer (ASCOLT) can improve survival in this patient population over placebo control. If indeed found to be beneficial, because aspirin is cheap and easy to administer, it will positively …

PIK3CA
colon cancer
rectal carcinoma
aspirin
Royal Brisbane and Women's Hospital
 (684.9 away) Contact site
  • 646 views
  • 07 Nov, 2020
  • +42 other locations
Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain

This is a Phase I/II, double-blind, parallel-group, randomized, placebo-controlled multi-centre trial in 180 patients randomized 1:1:1 to receive the IMP (Dexamethasone acetate microspheres for extended-release injectable micro-suspension, SX600 at 12.5 mg or 25.0 mg) or Placebo (0.9% Sodium Chloride for Injection, BP) via transforaminal epidural injection to the lumbosacral epidural …

Research Site 08
 (5.8 away) Contact site
  • 70 views
  • 29 Oct, 2020
  • +9 other locations
Adjuvant Chemotherapy With Gemcitabine and Cisplatin Compared to Standard of Care After Curative Intent Resection of Biliary Tract Cancer

This is a multicenter, prospective, randomized, controlled phase III trial designed to assess the clinical performance of gemcitabine with cisplatin and observation vs. standard of care (observation alone in stage 1 and capecitabine and observation in stage 2) in patients after curative intent resection of BTC including an embedded sub-study …

capecitabine
biliary disease
cisplatin/gemcitabine
gemcitabine
cancer
Royal Brisbane and Women's Hospital
 (684.9 away) Contact site
  • 458 views
  • 01 Oct, 2020
  • +68 other locations
Study of Ibrutinib and Rituximab in Treatment Na ve Follicular Lymphoma

The purpose of this study is to evaluate whether the addition of ibrutinib will result in prolongation of progression-free survival (PFS) when compared with rituximab alone in treatment nave subjects with follicular lymphoma.

ibrutinib
follicular lymphoma
measurable disease
rituximab
Mater Misericordiae Health Services
 (686.2 away) Contact site
  • 4546 views
  • 22 Nov, 2020
  • +216 other locations
Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301)

This Phase III study will be conducted to evaluate the efficacy and safety of YH25448 as first-line treatment in locally advanced or metastatic Non-small Cell Lung Cancer (NSCLC) patients with EGFR mutations

lung adenocarcinoma
lung carcinoma
measurable disease
stage iv non-small cell lung cancer
EGFR
Princess Alexandra Hospital
 (687.2 away) Contact site
  • 233 views
  • 11 Nov, 2020
  • +76 other locations
A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors

This trial will study ladiratuzumab vedotin (LV) to find out if it works to treat different types of solid tumors. It will also find out what side effects may occur. A side effect is anything the drug does besides treating cancer.

adenocarcinoma
epidermal growth factor receptor
extensive disease
chemoradiotherapy
growth factor
St Vincents Hospital Sydney
 (1037.7 away) Contact site
  • 12 views
  • 28 Oct, 2020
  • +42 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
cardiovascular disease
hemoglobin a1c
CORE Research Group Pty Ltd
 (684.8 away) Contact site
  • 593 views
  • 25 Nov, 2020
  • +807 other locations
Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate

The purpose of this study is to determine the effectiveness of darolutamide as part of adjuvant androgen deprivation therapy (ADT) with a luteinising hormone releasing hormone analogue (LHRHA) in men having radiation therapy for localised prostate cancer at very high risk of recurrence.

adenocarcinoma
antiandrogen therapy
gonadorelin
gonadotropin
neutrophil count
Townsville Hospital
 (5.8 away) Contact site
  • 62 views
  • 07 Oct, 2020
  • +30 other locations
Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

Mycobacterium abscessus (MABS) is a group of rapid-growing, multi-drug resistant non-tuberculous mycobacteria (NTM) causing infections in humans. MABS pulmonary disease (MABS-PD) can result in significant morbidity, increased healthcare utilisation, accelerated lung function decline, impaired quality of life, more challenging lung transplantation, and increased mortality. While the overall numbers affected is …

Townsville Hospital
 (5.8 away) Contact site
  • 117 views
  • 15 Jun, 2020
  • +35 other locations