Douglas, Australia Clinical Trials

A listing of Douglas, Australia clinical trials actively recruiting patients volunteers.

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Found 17 clinical trials
Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers

We hypothesize through this randomized, placebo-controlled adjuvant study, that Aspirin in patients with dukes C or high risk dukes B colorectal cancer (ASCOLT) can improve survival in this patient population over placebo control. If indeed found to be beneficial, because aspirin is cheap and easy to administer, it will positively …

PIK3CA
colon cancer
rectal carcinoma
aspirin
Royal Brisbane and Women's Hospital
 (684.9 away) Contact site
  • 646 views
  • 07 Nov, 2020
  • +42 other locations
Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile Infection

Summit is developing ridinilazole as a novel antimicrobial for Clostridium difficile Infection (CDI) with the goal of achieving comparable cure rates to standard of care, but reducing rates of recurrent disease. A phase 2 proof of concept study, with vancomycin as comparator, demonstrated these attributes with a comparable safety profile. …

diarrhea
ridinilazole
antibiotics
vancomycin
antibiotic therapy
Sunshine Coast University Hospital
 (650.3 away) Contact site
  • 101 views
  • 08 Jul, 2020
  • +223 other locations
Study of Ibrutinib and Rituximab in Treatment Na ve Follicular Lymphoma

The purpose of this study is to evaluate whether the addition of ibrutinib will result in prolongation of progression-free survival (PFS) when compared with rituximab alone in treatment nave subjects with follicular lymphoma.

measurable disease
rituximab
follicular lymphoma
ibrutinib
Mater Misericordiae Health Services
 (686.2 away) Contact site
  • 4546 views
  • 22 Nov, 2020
  • +216 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

myocardial infarction
stemi
percutaneous coronary intervention
diabetes
acute coronary syndrome
0360063 - Cairns Base Hospital
 (178.3 away) Contact site
  • 1118 views
  • 01 Dec, 2020
  • +3406 other locations
Adjuvant Chemotherapy With Gemcitabine and Cisplatin Compared to Standard of Care After Curative Intent Resection of Biliary Tract Cancer

This is a multicenter, prospective, randomized, controlled phase III trial designed to assess the clinical performance of gemcitabine with cisplatin and observation vs. standard of care (observation alone in stage 1 and capecitabine and observation in stage 2) in patients after curative intent resection of BTC including an embedded sub-study …

biliary disease
biliary tract cancer
capecitabine
gemcitabine
cancer
Royal Brisbane and Women's Hospital
 (684.9 away) Contact site
  • 458 views
  • 01 Oct, 2020
  • +68 other locations
A Study of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

The purpose of this study is to evaluate the efficacy and safety of Tislelizumab as first line treatment in combination with chemotherapy in participants with advanced unresectable/metastatic ESCC.

oxaliplatin
squamous cell carcinoma
fluorouracil
capecitabine
paclitaxel
Coffs Harbour Hospital
 (852.9 away) Contact site
  • 24 views
  • 23 Sep, 2020
  • +204 other locations
Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients

ICON 9 will assess the efficacy, safety and tolerability of maintenance olaparib in combination with cediranib compared to maintenance olaparib alone following a response to platinum-based chemotherapy in women with relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer. Prognostic and predictive factors will be studied from tumour and blood samples.

recurrent disease
olaparib
neutrophil count
measurable disease
tumor debulking
Townsville Hospital
 (5.8 away) Contact site
  • 392 views
  • 16 Sep, 2020
  • +40 other locations
A Phase 3 Efficacy Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer

A study of zolbetuximab (IMAB362) plus mFOLFOX6 versus placebo plus mFOLFOX6 in subjects with Claudin 18.2 positive, HER2-negative, locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical study for adult patients who have any of: advanced unresectable gastric …

Site AU61011
 (740.5 away) Contact site
  • 484 views
  • 27 Nov, 2020
  • +220 other locations
A Study of Venetoclax and Dexamethasone Compared With Pomalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

A study designed to evaluate the safety and efficacy of venetoclax plus dexamethasone (VenDex) compared with pomalidomide plus dexamethasone (PomDex) in participants with t(11;14)-positive Relapsed or Refractory Multiple Myeloma.

pomalidomide
proteasome inhibitor
lenalidomide
dexamethasone
measurable disease
Icon Cancer Care - Townsville /ID# 206565
 (3.9 away) Contact site
  • 91 views
  • 27 Nov, 2020
  • +221 other locations
Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia

This study will evaluate the efficacy of uproleselan (GMI-1271), a specific E-selectin antagonist, in combination with chemotherapy to treat relapsed/refractory AML, compared to chemotherapy alone. The safety of uproleselan when given with chemotherapy will also be investigated in patients with relapsed/refractory AML

refractory acute myeloid leukemia (aml)
Princess Alexandra Hospital
 (687.2 away) Contact site
  • 89 views
  • 21 Nov, 2020
  • +53 other locations