Douglas, Australia Clinical Trials

A listing of Douglas, Australia clinical trials actively recruiting patients volunteers.

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Found 22 clinical trials
Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers

We hypothesize through this randomized, placebo-controlled adjuvant study, that Aspirin in patients with dukes C or high risk dukes B colorectal cancer (ASCOLT) can improve survival in this patient population over placebo control. If indeed found to be beneficial, because aspirin is cheap and easy to administer, it will positively …

colon cancer
rectal carcinoma
aspirin
PIK3CA
Royal Brisbane and Women's Hospital
 (684.9 away) Contact site
  • 646 views
  • 07 Nov, 2020
  • +42 other locations
Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile Infection

Summit is developing ridinilazole as a novel antimicrobial for Clostridium difficile Infection (CDI) with the goal of achieving comparable cure rates to standard of care, but reducing rates of recurrent disease. A phase 2 proof of concept study, with vancomycin as comparator, demonstrated these attributes with a comparable safety profile. …

diarrhea
vancomycin
antibiotics
clostridium difficile
ridinilazole
Sunshine Coast University Hospital
 (650.3 away) Contact site
  • 101 views
  • 08 Jul, 2020
  • +223 other locations
Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain

This is a Phase I/II, double-blind, parallel-group, randomized, placebo-controlled multi-centre trial in 180 patients randomized 1:1:1 to receive the IMP (Dexamethasone acetate microspheres for extended-release injectable micro-suspension, SX600 at 12.5 mg or 25.0 mg) or Placebo (0.9% Sodium Chloride for Injection, BP) via transforaminal epidural injection to the lumbosacral epidural …

Research Site 08
 (5.8 away) Contact site
  • 70 views
  • 29 Oct, 2020
  • +9 other locations
Study of Ibrutinib and Rituximab in Treatment Na ve Follicular Lymphoma

The purpose of this study is to evaluate whether the addition of ibrutinib will result in prolongation of progression-free survival (PFS) when compared with rituximab alone in treatment nave subjects with follicular lymphoma.

measurable disease
rituximab
ibrutinib
follicular lymphoma
Mater Misericordiae Health Services
 (686.2 away) Contact site
  • 4546 views
  • 22 Nov, 2020
  • +216 other locations
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation …

myocardial infarction
acute coronary syndrome
infarct
stroke
percutaneous coronary intervention
0360063 - Cairns Base Hospital
 (178.3 away) Contact site
  • 1118 views
  • 25 Nov, 2020
  • +3405 other locations
A Phase 3 Efficacy Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer

A study of zolbetuximab (IMAB362) plus mFOLFOX6 versus placebo plus mFOLFOX6 in subjects with Claudin 18.2 positive, HER2-negative, locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical study for adult patients who have any of: advanced unresectable gastric …

Site AU61011
 (740.5 away) Contact site
  • 484 views
  • 25 Nov, 2020
  • +219 other locations
Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

Mycobacterium abscessus (MABS) is a group of rapid-growing, multi-drug resistant non-tuberculous mycobacteria (NTM) causing infections in humans. MABS pulmonary disease (MABS-PD) can result in significant morbidity, increased healthcare utilisation, accelerated lung function decline, impaired quality of life, more challenging lung transplantation, and increased mortality. While the overall numbers affected is …

Townsville Hospital
 (5.8 away) Contact site
  • 117 views
  • 15 Jun, 2020
  • +35 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
cardiovascular disease
hemoglobin a1c
CORE Research Group Pty Ltd
 (684.8 away) Contact site
  • 593 views
  • 25 Nov, 2020
  • +807 other locations
Australasian COVID-19 Trial (ASCOT)

An International Multi-Centre Randomised Clinical Trial to Assess the Clinical, Virological and Immunological Outcomes in Patients Diagnosed with SARS-CoV-2 Infection (COVID-19).

Townsville University Hospital
 (2.4 away) Contact site
  • 804 views
  • 25 Nov, 2020
  • +76 other locations
Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)

This study is designed to assess the safety and efficacy of lenvatinib in combination with pembrolizumab versus standard of care (SOC) chemotherapy, and to also assess the safety and efficacy of lenvatinib monotherapy in participants with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) that have progressed after platinum …

chemotherapy regimen
caries
docetaxel
carcinoma
paclitaxel
Greenslopes Private Hospital ( Site 0105)
 (689.4 away) Contact site
  • 0 views
  • 25 Nov, 2020
  • +25 other locations