Chermside, Australia Clinical Trials

A listing of Chermside, Australia clinical trials actively recruiting patients volunteers.

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Found 393 clinical trials
A Study of Lenvatinib (MK-7902) in Pediatric Participants With Relapsed or Refractory Solid Malignancies (MK-7902-013/E7080)

The main purpose of this study is to evaluate the antitumor activity and safety of Lenvatinib (MK-7902/E7080) in children, adolescents, and young adults with relapsed or refractory solid malignancies after administration. Participants will be enrolled into initial tumor-specific cohorts which will be expanded based on observed response.

Queensland Children s Hospital ( Site 0804)
 (6.6 away) Contact site
  • 0 views
  • 23 Jul, 2021
  • +48 other locations
Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

The study is to evaluate the efficacy and safety of evobrutinib administered orally twice daily versus Teriflunomide (Aubagio), administered orally once daily in participants with Relapsing Multiple Sclerosis (RMS).

evobrutinib
teriflunomide
aubagio
Research Site 104
 (6.6 away) Contact site
  • 0 views
  • 25 Jul, 2021
  • +269 other locations
An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Dimethyl Fumarate or Fingolimod to Ofatumumab

The open label study to evaluate effectiveness of treatment with ofatumumab in patients transitioning from commonly used oral MS therapies - fingolimod or dimethyl fumarate, due to breakthrough disease.

dimethyl fumarate
ofatumumab
fingolimod
Novartis Investigative Site
 (6.9 away) Contact site
  • 0 views
  • 22 Jul, 2021
  • +116 other locations
Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).

This study is a Phase 3 global, multicenter, placebo-controlled double-blind randomized study that will enroll participants with inoperable locally recurrent or metastatic SCAC not previously treated with systemic chemotherapy.

Princess Alexandra Hospital Australia
 (6.9 away) Contact site
  • 0 views
  • 19 Jun, 2021
  • +83 other locations
Study of REGN2810 in Patients With Advanced Cutaneous Squamous Cell Carcinoma

For Groups 1 to 4, the primary objective of this study is to estimate the clinical benefit of cemiplimab monotherapy for patients with: metastatic (nodal or distant) cutaneous squamous cell carcinoma (CSCC), or unresectable locally advanced CSCC. For Group 6, the primary objective is to provide additional efficacy and safety …

Royal Brisbane & Women's Hospital
 (4.2 away) Contact site
  • 0 views
  • 28 Jan, 2021
  • +102 other locations
Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)

This is an open-label, randomized, multi-center, comparator Phase II trial looking at the addition of Bevacizumab to Vinblastine in chemotherapy nave pediatric patients with progressive Low Grade Glioma aged 6 months to less than18 years of age at the time of initiation of therapy. Participants will be randomized to Arm …

progressive disease
auditory test
corticosteroids
vinblastine
platelet count
Queensland Children's Hospital
 (6.3 away) Contact site
  • 0 views
  • 24 Jan, 2021
  • +23 other locations
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)

This is a prospective, multicenter, open-label, randomized, controlled, parallel group, group-sequential, event-driven Phase 3 study to evaluate efficacy, safety and pharmacokinetics (PK) of macitentan in children.

heart disease
connective tissue disease
hypertension
macitentan
Lady Cilento Children's Hospital
 (6.3 away) Contact site
  • 172 views
  • 16 Jun, 2021
  • +106 other locations
A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

rituximab
bendamustine
cyclin d1
acalabrutinib
Research Site
 (4.3 away) Contact site
  • 1270 views
  • 24 Jul, 2021
  • +250 other locations
Androgen Deprivation Therapy in Treating Patients With Prostate Cancer

RATIONALE: Androgens can cause the growth of prostate cancer cells. Androgen deprivation therapy may stop the adrenal glands from making androgens. PURPOSE: This randomized phase III trial is studying how well androgen deprivation therapy works in treating patients with prostate cancer.

antiandrogens
antiandrogen therapy
androgen suppression
androgens
orchiectomy
Royal Brisbane and Women's Hospital
 (4.2 away) Contact site
  • 401 views
  • 07 Nov, 2020
  • +8 other locations
Phase ll Study of Pirfenidone in Patients With RAILD (TRAIL1)

The purpose of this study is to to assess the safety and tolerability of pirfenidone 2403 mg/day for the treatment of RA-associated interstitial lung disease.

Royal Prince Alfred Hospital
 (460.9 away) Contact site
  • 207 views
  • 23 Jan, 2021
  • +30 other locations