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  • Development of Isthmocele Symptom Severity and Quality of Life Scale

    Patients with isthmocele symptoms three months after cesarean delivery will be included in the study.The study will not include findings that may be confused with isthmocele symptoms, such as uterine fibroids and endometrial polyps. Patients with acute vaginitis and pelvic inflammatory disease will not be included in the study.

    Phase

    N/A

    Span

    157 weeks

    Sponsor

    Hilal Yuvacı

    Sakarya

    Recruiting

  • A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 1)

    Phase

    3

    Span

    136 weeks

    Sponsor

    Sanofi

    Sakarya

    Recruiting

  • Safety, Effectiveness, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

    Each substudy contains a Phase 2 part followed by a Phase 3 part. Participants will be randomized to one of two dose levels of BNT327 plus chemotherapy for the Phase 2 part of each substudy. After the analysis of the Phase 2 data (efficacy, safety, and exposure-response), an internal review committee (IRC) will decide whether participants will be treated with BNT327 at dose level 1 or 2 in the Phase 3 part of the substudies. After dose selection, the selected dose will be used for all participants in the study. For the Phase 3 parts of both substudies, an independent data monitoring committee (IDMC) will be established as needed to provide independent review of the data during the study. The sponsor may decide not to perform or stop recruiting participants in the Phase 2 part of the study depending on data generated in the BNT327-01 (NCT06449209) and BNT327-02 (NCT06449222) studies. The sponsor may also choose not to continue all substudies.

    Phase

    2/3

    Span

    312 weeks

    Sponsor

    BioNTech SE

    Sakarya

    Recruiting

  • A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)

    Phase

    3

    Span

    180 weeks

    Sponsor

    Bristol-Myers Squibb

    Sakarya

    Recruiting

  • A Trial to Learn if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

    Phase

    3

    Span

    265 weeks

    Sponsor

    Regeneron Pharmaceuticals

    Sakarya

    Recruiting

  • A Study to Learn More About How Well BAY 2927088 Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Human Epidermal Growth Factor Receptor 2 (HER2)

    Phase

    3

    Span

    244 weeks

    Sponsor

    Bayer

    Sakarya

    Recruiting

  • Motivation in Learning Medical Terminology

    Medical Terminology is a specialized language system that expresses the meanings and structures of terms used in the field of medicine. These terms are often of Latin and Greek origin and are widely used in medical documentation, communication, and education (Ismayilli Karakoc, 2020). The education of medical terminology is crucial for healthcare professionals to communicate effectively, understand medical documents, and have accurate knowledge about diseases. Additionally, the use of correct terms helps prevent errors (Antoniou et al., 2011). Traditionally, textbooks and courses have played a fundamental role in teaching medical terminology to students, presenting structured content for learning basic terms (Sharipov et al., 2023). Nowadays, active methods used in medical terminology education include Flashcards, Online Resources and Applications, Scenario-Based Learning, and Mind Mapping (Alizadeh et al., 2021; Grezes & Decety, 2001; Hsu & Chen, 2023; Liu et al., 2017). According to the literature, students' motivation has a significant impact on language education. Motivated students show more participation in classes, dedicate more time to the learning process, and achieve higher success (Grezes & Decety, 2001). Medical terminology education is especially important for nursing and midwifery students. Studies suggest that using correct terms in these professions ensures effective communication with patients and the accurate execution of treatment processes (Stedman, 2005). In this study, students studying medical terminology at the Faculty of Health Sciences were evaluated for their learning motivation. The study population consists of students in the 2nd year of the Nursing and Midwifery Department at Sakarya University Faculty of Health Sciences between October 2023 and January 2024. This study is based on the voluntary participation of students. The participants were divided into three groups based on their preferences. In addition to the traditional teaching methods (PowerPoint), one group will receive medical terminology English training through the "Funny Scenario-Based Learning" method, while the other group will receive training through the "Mind Mapping" method. Through this mechanism, they were able to cultivate a sense of responsibility and a sense of ownership in their educational journey. Consequently, it is anticipated that such autonomy could boost their motivation and engagement, potentially enhancing their educational performance. Specifically, students who engage in funny scenario-based education prefer to collaborate with peers who share similar interests and learning styles, which makes preparing scenarios more enjoyable. A self-directed grouping likely fosters an environment of idea exchange, mutual encouragement, and collaborative assistance, resulting in a synergistic and supportive learning culture. As a result of peer support, students may be motivated by peer recognition, receive constructive feedback, and experience social interaction. Meanwhile, in the mind-mapping groups, students draw on their creative skills to deconstruct and assimilate unfamiliar terms, utilizing their sense of humor and artistic competencies. As a result of this approach, students are required to engage actively with the content, allowing them to encode information in a creative and effective way. The control group will only receive traditional teaching methods (PowerPoint). After the study, the control group will also experience "Funny Scenario-Based Learning" and "Mind Mapping." The researchers will use the Scale of English Learning Motivation for Students Studying in the Faculty of Health Sciences as a pre-test and post-test for data collection. The motivation levels of all three groups will be evaluated both before and after using the "English Learning Motivation Scale." Data collection tools include: 1. Student Information Questionnaire: This questionnaire consists of approximately 10 questions, capturing students' identifying information, including sociodemographic and academic details. 2. Scale of English Learning Motivation for Students in the Faculty of Health Sciences: This scale, developed by DEMİR and HAMARAT in 2022, comprises 14 items divided into three sub-dimensions (intrinsic motivation with 5 items, extrinsic (instrumental) motivation with 5 items, and integrative motivation with 4 items). All items on the scale are arranged in a five-point Likert scale ranging from "completely disagree" to "completely agree." The scoring of items on the scale is done on a Likert scale of 1 = definitely disagree to 5 = definitely agree. The evaluation of scores is based on the sum of item scores obtained from each factor. The scores obtained from each dimension of the scale can be ranked as follows: "Intrinsic motivation" and "Extrinsic motivation" factors can range from 5 to 25, while the "Integrative motivation" factor can range from 4 to 20. The total of the scale cannot be found by adding up the total scores because the scale is not a summation. A higher score obtained from any dimension indicates effectiveness in learning motivation. Additionally, there are no items reversed in the scale, and all items are formulated with positive expressions.

    Phase

    N/A

    Span

    31 weeks

    Sponsor

    Sakarya University

    Sakarya

    Recruiting

    Healthy Volunteers

  • A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With Previously Treated Aggressive B-cell Non-Hodgkin Lymphoma

    Phase

    3

    Span

    170 weeks

    Sponsor

    Regeneron Pharmaceuticals

    Sakarya

    Recruiting

  • Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab

    Phase

    3

    Span

    217 weeks

    Sponsor

    Amgen

    Sakarya

    Recruiting

  • A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Participants With Follicular Lymphoma

    Phase

    3

    Span

    278 weeks

    Sponsor

    Regeneron Pharmaceuticals

    Sakarya

    Recruiting

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