Rosario, Argentina Clinical Trials

A listing of Rosario, Argentina clinical trials actively recruiting patients volunteers.

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Found 6 clinical trials
Dolutegravir and Darunavir Evaluation in Adults Failing Therapy

DEFT is a randomised, open-label study in HIV-1 infected patients failing first-line antiretroviral therapy (ART). The study compares 2 regimens of second-line ART (dolutegravir and darunavir pharmaco-enhanced with ritonavir and dolutegravir and 2 prespecified NRTIs) with the WHO recommended regimen of 2NRTIs plus a ritonavir-boosted PI (Standard of Care (SOC)). …

antiretroviral
dolutegravir
reverse transcriptase inhibitor
HIV Vaccine
darunavir
Hospital Dr Diego Paroissien
 (167.9 away) Contact site
  • 1172 views
  • 25 Mar, 2021
  • +31 other locations
Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis (PBC) is a serious, life-threatening, bile acid related liver disease of unknown cause. Without treatment, it frequently progresses to liver fibrosis and eventual cirrhosis requiring liver transplantation or resulting in death. The investigational drug, Obeticholic Acid (OCA) is a modified bile acid and FXR agonist that is …

fibrosis
glutaric acid
cholangitis
investigational drug
obeticholic acid
Hospital Provincial del Centenario
 (5.6 away) Contact site
  • 402 views
  • 27 May, 2021
  • +322 other locations
Durvalumab Long-Term Safety and Efficacy Study

The aims of the study are to monitor the long-term safety of durvalumab, to provide continued treatment or retreatment with durvalumab to eligible patients, and to collect overall survival (OS) information.

cancer treatment
antineoplastic
Research Site
 (2.6 away) Contact site
  • 23 views
  • 20 Jul, 2021
  • +176 other locations
Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity Mortality and NT-proBNP Change in Patients With CCC

The purpose of this study is to evaluate the effect of sacubitril/valsartan 200 mg BID compared with enalapril 10 mg BID, in addition to conventional heart failure (HF) treatment, in improving a hierarchical composite of cardiovascular (CV) events (i.e. CV death or the occurrence of first HF hospitalization) and causing …

natriuretic peptide
valsartan
serology test
ejection fraction
nt-probnp
Novartis Investigative Site
 (2.6 away) Contact site
  • 0 views
  • 09 Apr, 2021
  • +4 other locations
A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)

The goal of this study is to evaluate the efficacy and safety of pembrolizumab combined with carboplatin and paclitaxel as first line treatment in participants with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). No statistical hypothesis will be tested in this study.

carboplatin
carcinoma
squamous cell carcinoma
paclitaxel
mk-3475
Hospital Provincial del Centenario ( Site 0304)
 (2.6 away) Contact site
  • 0 views
  • 19 Jul, 2021
  • +28 other locations
Comparison of Vortioxetine and Desvenlafaxine in Adult Patients Suffering From Depression

The purpose of this study is to compare the efficacy of vortioxetine versus desvenlafaxine after 8 weeks of treatment in patients that have tried one available treatment without getting the full benefit

antidepressants
selective serotonin reuptake inhibitors
sertraline
vortioxetine
paroxetine
CIAP (Centro de Investigacion y Asistencia en Psiquiatria) (AR1013)
 (1.4 away) Contact site
  • 0 views
  • 28 Jun, 2021
  • +85 other locations