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Manic Disorders Clinical Trials

A listing of Manic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (164) clinical trials

Pregnant Women Taking Lamictal for Bipolar Disorder

There is an increased risk of recurrence of Bipolar Disorder (BD) episodes or worsening symptoms in pregnancy after the discontinuation of mood stabilizers. Similarly, changes in medication concentration due to the physiological changes in pregnancy may effectively reduce the medication dose and thus its efficacy in pregnancy. Therapeutic dose monitoring ...

Phase N/A

Emotions in Schizophrenia and Bipolar Disorders: a Common Vulnerability?

The aim of this proposal is to investigate disturbances of understanding of "emotional language" in schizophrenia and bipolar disorder. By "emotional langague", the investigators mean emotions wich can be drawn from utterances, thanks to affective valence of words or phrases, expression of emotional state or prosody. Schizophrenia and bipolar disorder ...

Phase N/A

Study of the Genetic and Environmental Factors of Vulnerability in Bipolar Disorders

Bipolar disorder is a complex, multifactorial disorder with the intervention of genetic vulnerability factors. To help the identification of these genetic factors and to improve genotype-phenotype correlation, the identification of endophenotype through the exploration of vulnerability characteristics in unaffected first degree relatives have been recommended. For this purpose, the investigator ...

Phase N/A

Mental Time Travel and Identity in Bipolar Disorder Patients

Study design: case / control study in inclusion prospective, single center. population: A group of 30 patients aged 18 to 60 years and followed in the psychiatry department of adult CHU Reims for bipolar disorder type I (DSM-IV criteria). A group of 30 control subjects with no personal or family ...

Phase N/A

Effectiveness of TCC Followed by MBCT and Predictive Factors (Genetic Clinical and Cognitive) Response

In recent years, various controlled studies showed that psychoeducational interventions have been effective in decreasing relapse and improving outcomes for bipolar disorders. However, samples were often small, compromising statistical power, and with a large variety of patients. The investigators therefore tested if a CBT group psychoeducation program + MBCT decreased ...

Phase N/A

Effects of Erythropoietin on Cognition and Neural Activity in Bipolar Disorder

This trial will include healthy first-degree relatives (sub-study 1) and bipolar disorder (BD) patients in partial or full remission (defined as a score of 14 on the Hamilton Depression Rating Scale 17-items and the Young Mania Rating Scale (sub-study 2) with objectively-verified cognitive dysfunction. Participants will be recruited from Psychiatric ...


Pharmacoepigenetics of Bipolar Disorder Treatment

This study will be composed of 2 visits. The first visit will be used as a screening visit for inclusion of the three groups of patients for the second visit where the outcomes will be collected (e.g., tissue samples for DNA methylation and lipidomic analysis).

Phase N/A

DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder

The primary objective of this study is to evaluate under double blind conditions the dose tolerance and safety of extended release Equetro (carbamazepine) versus placebo followed by an open label and long term maintenance treatment on extended release Equetro in children and adolescents aged 10-17 year diagnosed with acute manic ...


PET and MRI Brain Imaging of Bipolar Disorder

PET and MRI imaging will be used to investigate the aims described above in patients who have bipolar disorder or unipolar depression and are currently experiencing a depressive episode. Both healthy controls and depressed participants with bipolar disorder or unipolar depression will be recruited. Patients who are on medication before ...

Phase N/A

Magnesium Variations and Cardiometabolic Risk in Patients With Antipsychotic Drugs

This is a pilot single-center prospective cohort. After inclusion, patients status (including magnesium levels) will be evaluated (1 and 3 months of treatment) and that status will define the exposure criterion. Included patients will be followed for 1 year during which cardiometabolic markers will be measured. Patients will be recruited ...

Phase N/A