Manic Disorders Clinical Trials

A listing of Manic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 230 clinical trials
The CAG Bipolar the CAG Bipolar RCT

)) improves lives and outcomes for patients with bipolar disorder (N= 1000 patients).

bipolar disorder
  • 2 views
  • 24 Jan, 2021
  • 1 location
Enhancing Cognitive Reserve of the Offsprings of Bipolar and Schizophrenic Patients

The high hereditary component and the contribution of neurodevelopmental processes in bipolar disorder and schizophrenia means implies the children of these patients are considered a high risk

  • 0 views
  • 22 Jan, 2021
Optimal Electrical Stimulus During Electroconvulsive Therapy

(decrease of 50% on the MADRS-S) number of ECTs in the treatment series readmission and suicide rate within 6 months Study population: patients with unipolar or bipolar depression. Sample size: 800 patients

remission
suicide
depressive episode
depressed mood
depression
  • 98 views
  • 25 Jan, 2021
  • 2 locations
A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive With or Without Mixed Features

(i.e. index episode) is manic or depressive, with or without mixed features; 2) To evaluate the efficacy and safety of cariprazine at a target dose of 1.5 mg/d compared with placebo in prevention of

bipolar i disorder
mania
cariprazine
tension
psychiatric disorder
  • 8584 views
  • 31 May, 2021
  • 157 locations
Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors

The goals of this study are to replicate previous findings of genetic predictors of response to clozapine and other antipsychotic drugs.

clozapine
schizophrenia
major depressive disorder
depression
psychosis
  • 300 views
  • 07 Nov, 2020
  • 1 location
Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach

The purpose of this research is to determine whether there is more extensive inflammation in the brain of people with clinical evidence of neuropsychiatric syndromes, such as mood disorder, chronic pain syndrome, dementia, traumatic brain injury, or substance abuse. The research will also explore whether there is more inflammation in …

  • 6 views
  • 22 Jan, 2021
  • 1 location
Definitive Selection of Neuroimaging Biomarkers for the Diagnosis and Treatment to Common Mental Disorders

To explore the whole-brain anatomical and functional abnormalities in drug-naive patients with schizophrenia ,drug-naive patients with BD, drug-naive patients with MDD and healthy controls by using a combination of cross-sectional and longitudinal study designs, including a longitudinal study with 8 weeks of drugs treatment. And explore whether there are shared …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Treatment of Marijuana Withdrawal Syndrome Using Escitalopram and Cognitive-Behavior Therapy

Recent studies have established the reliability, validity and time course of the cannabis withdrawal syndrome. This study will investigate the effects of combined treatment of Escitalopram with cognitive-behavior therapy in alleviating the symptoms of the marijuana withdrawal syndrome in regular chronic users of marijuana. We predict that combined pharmacological treatment …

cannabis withdrawal
withdrawal symptoms
escitalopram
  • 14 views
  • 07 Nov, 2020
  • 1 location
add-on Low Dose Memantine in Middle-to-old Aged Bipolar II Disorder Patients

The investigators hypothesized that add-on memantine (MM) 5 mg/day may reduce chronic inflammation, and subsequently improve neuro-progression process and cognitive function in middle-to-old aged bipolar II disorder (BP-II) patients. In current proposal, the investigators will conduct a randomized double-blind placebo-controlled study. The investigators will recruit 100-120 patients with BP-II who …

  • 0 views
  • 19 Mar, 2021
  • 1 location
Repetitive Transcranial Magnetic Stimulation for Adolescent Depression: Efficacy Predictive Biomarkers and Mechanisms

This study will be an open-label 6-week (30 session) trial of active repetitive transcranial magnetic stimulation (rTMS) using a fixed frequency (10 Hz) but varying stimulation intensities using a 3+3 study design for safety and tolerability amongst adolescents. This means that we will only enroll 3 participants at a time …

depressive disorder
transcranial magnetic stimulation
  • 113 views
  • 25 Jan, 2021
  • 1 location