Manic Disorders Clinical Trials

A listing of Manic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 69 clinical trials
Multi-modal Assessment of GABA Function in Psychosis (GABAmech)

The purpose of this study is to better understand mental illness and will test the hypotheses that while viewing affective stimuli, patient groups will show increased blood oxygenation level dependent (BOLD) signal by fMRI after lorazepam. This study will enroll participants between the ages of 16 and 60, who have …

bipolar disorder
psychotic symptoms
major depressive disorder
psychosis
remission
  • 165 views
  • 12 Oct, 2022
  • 1 location
Can Neural Network Instability in Schizophrenia be Improved With a Very Low Carbohydrate Ketogenic Diet?

Wide ranging cognitive deficits are major drivers of functional decline and poor outcomes in people with schizophrenia (SZ) and bipolar disorder (BD). Medications do not target

diabetes
cognitive impairment
schizophrenia
schizoaffective disorder
scid
  • 0 views
  • 21 Oct, 2022
  • 1 location
Enhancement of a Psychotherapeutic Intervention Through Transcranial Direct Current Stimulation (tDCS)

participants with several neuropsychiatric disorders, including major depression, bipolar disorder, schizophrenia and substance use disorder are encouraging. The clinical effects of tDCS are broad; the

depression
depressive disorder
substance use
schizophrenia
bipolar disorder
  • 0 views
  • 11 Oct, 2022
  • 1 location
Passive Mobile Self-Tracking of Mental Health by Veterans With Serious Mental Illness

Serious mental illnesses require years of monitoring and adjustments in treatment. Stress, substance abuse or reduced medication adherence cause rapid worsening of symptoms, with consequences that include job loss, homelessness, suicide, incarceration, and hospitalization. Treatment visits can be infrequent. Illness exacerbations usually occur with no clinician awareness, leaving little opportunity …

suicide
schizophrenia
schizoaffective disorder
bipolar disorder
psychiatric symptoms
  • 23 views
  • 24 Oct, 2022
  • 1 location
ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention

Psychosis is a disabling condition that typically has its onset in adolescence and early adulthood. Many young people with psychosis have difficulty navigating services or are reluctant to engage in treatment until their illness becomes an emergency. Consequently, nearly half of all new psychotic disorders are diagnosed in the emergency …

addiction
psychosis
  • 30 views
  • 07 Oct, 2022
  • 1 location
Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

This research study evaluates the effects of an FDA-approved medication Gabapentin in individuals with Bipolar Disorder who smoke marijuana. Participants in the study will will be assigned to

divalproex sodium
brain imaging
lithium
carbamazepine
schizoaffective disorder
  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy of the Mobile Application for Prediction and Prevention of Mood Episode Recurrence Based on Machine Learning

depressive disorders, bipolar disorders type 1 and 2) based on machine learning.

depressive disorder
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Feasibility Study of Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

Background People with TRD are often helped by electroconvulsive therapy (ECT). But ECT can affect memory and thinking. Researchers want to study a treatment called TEST that uses less electricity. Objective To study the safety and feasibility of TEST and assess its antidepressant effects. Eligibility Adults aged 25-64 with major …

depression
depressed mood
electroconvulsive therapy
  • 6 views
  • 22 Oct, 2022
  • 1 location
A 6-week, Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled Study of the Efficacy and Safety of Cariprazine in Pediatric Participants (10 to 17 Years of Age) in the Treatment of Depressive Episodes Associated With Bipolar I Disorder

Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive

depressive episode
depressed mood
mood disorder
  • 46 views
  • 25 Oct, 2022
  • 25 locations
Academic-Community EPINET (AC-EPINET): Mitigating Barriers to Care PILOT (AC-EPINET)

The investigators propose to examine the effects of CSC services delivered via TH (CSC-TH) versus the standard clinic-based CSC model (CSC-SD) on engagement and outcomes in a 12-month, randomized trial.

depression
bipolar disorder
a 12
schizophrenia
  • 9 views
  • 23 Oct, 2022
  • 6 locations