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Depression (Major/Severe) Clinical Trials

A listing of Depression (Major/Severe) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (45) clinical trials

The California Clinical Trials Medical Group managed by PAREXEL located in Glendale, CA is looking for people with depression to participate in a research study that will evaluate the efficacy of a new investigational medication for the treatment of depression. The study may involve up to 2 screening visits, 5 ...

Phase

This study will evaluate the long-term safety and tolerability of rapastinel as an adjunctive to antidepressant therapy (ADT) in patients with major depressive disorder (MDD).

Phase

The purpose of this study is to evaluate the efficacy, safety, and tolerability of levomilnacipran ER relative to placebo in adolescent outpatients (12-17 years) with Major Depressive Disorder (MDD). In addition, the study is designed to obtain pharmacokinetics (PK) data to guide dose selection for future pediatric studies of levomilnacipran.

Phase

Dr. Charles Conway is conducting a research study looking at adaptive enhanced transcranial direct current stimulation (tDCS) as adjunctive therapy for major depression. This study lasts 6 weeks. There will be up to 24 study visits that will last 30 minutes to 3 hours each. Participants will undergo 20 sessions ...

Phase N/A

This study will evaluate the efficacy, safety and tolerability of rapastinel 450 milligrams (mg) intravenous (IV) once weekly or once every 2 weeks versus placebo as an adjunctive treatment to ongoing anti-depressive therapy (ADT) in the prevention of relapse in participants with Major Depressive Disorder (MDD).

Phase

This study will assess the safety and efficacy of an investigational medication in patients with Major Depressive Disorder who have had a partial response to their antidepressant treatment. Each patient will receive a weekly intravenous dose of the investigational medication in addition to the current dose of their antidepressant.

Phase N/A

Looking for individuals to participate in a nationwide clinical research study of an investigational drug for Major Depressive Disorder and currently taking medication for it.

Phase

A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MUTLICENTER STUDY OF RAPASTINEL AS ADJUNCTIVE THERAPY IN MAJOR DEPRESSIVE DISORDER

Phase

A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MUTLICENTER STUDY OF RAPASTINEL AS ADJUNCTIVE THERAPY IN MAJOR DEPRESSIVE DISORDER

Phase

A clinical research study to evaluate the safety, effectiveness and tolerability of an investigational drug for individuals with Major Depressive Disorder.

Phase