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Depression (Major/Severe) Clinical Trials

A listing of Depression (Major/Severe) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (60) clinical trials

Dr. Charles Conway is conducting a research study looking at adaptive enhanced transcranial direct current stimulation (tDCS) as adjunctive therapy for major depression. This study lasts 6 weeks. There will be up to 24 study visits that will last 30 minutes to 3 hours each. Participants will undergo 20 sessions ...

Phase N/A

This study will evaluate the efficacy, safety and tolerability of rapastinel 450 milligrams (mg) intravenous (IV) once weekly or once every 2 weeks versus placebo as an adjunctive treatment to ongoing anti-depressive therapy (ADT) in the prevention of relapse in participants with Major Depressive Disorder (MDD).

Phase

A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MUTLICENTER STUDY OF RAPASTINEL AS ADJUNCTIVE THERAPY IN MAJOR DEPRESSIVE DISORDER

Phase

A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MUTLICENTER STUDY OF RAPASTINEL AS ADJUNCTIVE THERAPY IN MAJOR DEPRESSIVE DISORDER

Phase

The purpose of this study is to evaluate the efficacy of sirukumab as adjunctive treatment to antidepressant therapy, where sirukumab is measured over a 12 week study period for treatment of depression symptoms.

Phase

The purpose of the study aims to determine whether different concentrations of nitrous oxide (N2O) have different antidepressant effects for adults with treatment-resistant major depression. There are up to 14 study visits ranging from 1 to 4 hours each. There will be vital sign collection, and questionnaires throughout the study. ...

Phase N/A

California Neuroscience Research is conducting a research study to evaluate an investigational medication in persons with treatment resistant Major Depressive Disorder. Study Description A Randomized, Double-blind, Active- controlled Trial to Assess the Efficacy and Safety of Administered Orally to Subjects with Treatment Resistant Major Depressive Disorder.

Phase N/A

A Research Study is being conducted to evaluate an investigational product to be used for the treatment of Major Depressive Disorder (or MDD) in women. Qualified participants receive study-related care, and exams at no charge, in addition to compensation for time and effort.

Phase N/A

To assess the long-term safety and tolerability of ALKS 5461 for use as an adjunctive therapy to antidepressants for the treatment of major depressive disorder (MDD)

Phase

To evaluate the efficacy of ALKS 5461 for the adjunctive treatment of major depressive disorder (MDD) in adults who have an inadequate response to antidepressant therapy (ADT). To evaluate the safety and tolerability of ALKS 5461 in adults who have MDD and an inadequate response to ADT.

Phase