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Macular Degeneration Clinical Trials

A listing of Macular Degeneration medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (153) clinical trials

Study of Dark Adaptation in Age-Related Macular Degeneration

Objective: This study is designed to investigate the use of dark adaptation as a functional endpoint for progression of eyes with no to intermediate age-related macular degeneration (AMD). Study Population: Two hundred forty (240) participants will be initially accrued; however, up to 280 participants who meet the eligibility criteria may ...

Phase N/A

Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias

If you decide to participate in this study, we will collect 1 tablespoon (15 milliliters) of blood during the first/screening visit in order to extract your DNA. The sample will be sent to the research laboratory of Dr Stefan Pulst at the University of Utah for the study of genetic ...

Phase N/A

Aflibercept in Recurrent or Persistent CNV

Age-related macular degeneration (AMD) and diabetic retinopathy are among the most common disorders causing visual disability in elderly people. AMD leads to dysfunction and loss of photoreceptors in the central retina. Neovascular AMD (nAMD) affects visual function early in the disease process. The purpose of the study is to evaluate ...

Phase N/A

Phase I/II Follow-up Study of SAR422459 in Patients With Stargardt's Macular Degeneration

Patients will be followed for 15 years after completion/early termination from the previous TDU13583 study (NCT01367444). No treatment with study drug is administered in this LTS13588 study. Patients are only followed after treatment with SAR422459 in previous TDU13583 study.

Phase

High Resolution Retinal Imaging

Studying the morphology and function of the normal and diseased retina in vivo is needed for advancing the detection, diagnosis, and treatment of retinal disease. This protocol uses an adaptive optics scanning laser ophthalmoscope (AOSLO) to image the normal and diseased retina with individual cellular resolution non-invasively. The primary objective ...

Phase N/A

Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection

Ascertain the long term safety and efficacy of ziv-aflibercept in a large variety of ocular diseases and over a long-term after its proven safety and efficacy in the laboratory, in phase one study and in isolated case report. Background and Significance: Anti-VEGF therapy is currently one of the mainstay of ...

Phase

Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degeneration

Objective: Age-related macular degeneration (AMD), the leading cause of blindness in people over age 65 in the United States, is a heterogeneous clinical entity in which retinal degeneration occurs predominantly in the macula in the context of aging and leads to impairment of central visual acuity (VA). AMD occurs in ...

Phase

Smartphone Flicker Fusion Test for Patients With Optic Disorders.

The smartphone app developed is a flicker fusion that presents the subject with a series of stimuli consisting of a flickering pattern of bars above or below a static rectangle. For each stimulus presentation, the user has to tap the region that is flickering. The duration of the app is ...

Phase N/A

Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pseudodrusen) and Delayed Dark Adaptation

Objective: The objective of this study is to investigate the potential efficacy of vitamin A palmitate in improving dark adaptation in participants with age-related macular degeneration (AMD) and abnormal dark adaptation. Study Population: Ten participants will be initially accrued, however, up to twenty participants with AMD who meet the eligibility ...

Phase N/A

Vitamin A Palmitate Supplementation in Patients With Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation

Objective: The objective of this study is to investigate the potential efficacy of vitamin A palmitate in improving dark adaptation in participants with reticular pseudodrusen (RPD) and abnormal dark adaptation. Study Population: Ten participants will be initially accrued, however, up to twenty participants with RPD who meet the eligibility criteria ...

Phase N/A