Advanced Malignancies Clinical Trials

A listing of Advanced Malignancies medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 856 clinical trials
None
Phase I Study of CPI-300 in Patients With Advanced Tumors

This is a prospective, open-label, single arm, non-randomized study of CPI-300 in patients with advanced tumors. CPI-300 is administered via intravenous infusion using an accelerated titration

  • 0 views
  • 10 Aug, 2021
  • 2 locations
None
A Phase I Open-label Study for Subjects With Advanced Malignancies

This is a first-in-human (FIH) Phase 1 dose escalation study to evaluate the safety, tolerability, PK, PD, and preliminary activity of PT01 administered IV in subjects with advanced malignancies

  • 0 views
  • 22 Aug, 2021
  • 3 locations
None
Hepatic Impairment Study for Lorlatinib in Cancer Patients

This is a phase 1 study in advanced cancer patients with varied hepatic fucntions to evaluate the potential effect of hepatic impairment on pharmacokinetics and safety of lorlatinib and provide

  • 0 views
  • 25 Sep, 2021
  • 19 locations
None
A Study Evaluating the Safety Tolerability and Initial Efficacy of IBI110 in Subjects With Advanced Malignant Tumors

This is an open-label, dose escalation, Phase I study to evaluate the safety, tolerability, pharmacokinetics and efficacy of IBI110 in subjects with advanced malignancies.

measurable disease
lymphoma
solid tumor
  • 3 views
  • 24 Jan, 2021
None
A Study Evaluating the Safety Tolerability and Initial Efficacy of Recombinant Human Anti-T-cell Immunoreceptor With Ig and ITIM Domains (TIGIT) Monoclonal Antibody Injection (IBI939) in Subjects With Advanced Malignant Tumors

This is an open-label, dose escalation, Phase I study to evaluate the safety, tolerability, pharmacokinetics and efficacy of IBI939 in subjects with advanced malignancies

  • 0 views
  • 27 Jan, 2021
  • 1 location
None
A Clinical Trial to Evaluate AZD7648 Alone and in Combination With Other Anti-cancer Agents in Patients With Advanced Cancers.

-cancer agents in participants with advanced malignancies.

oophorectomy
antineoplastic
  • 14 views
  • 01 Nov, 2021
  • 6 locations
None
Phase I Clinical Trial of Human Anti-PD-L1 Antibody Injection (LDP) in Patients With Advanced Malignant Tumors

This is a phase I, open-label, multiple-dose, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics and anti-tumor activity of LDP in subjects with advanced malignant

  • 5 views
  • 23 Jan, 2021
  • 1 location
None
To Evaluate the Safety and Pharmacokinetics of Parscaclisib in Participants With Normal Renal Function and Renal Impairment.

The purpose of the study is to evaluate the pharmacokinetics and safety of parsaclisib in participants With normal renal function and participants with renal impairment.

  • 0 views
  • 25 May, 2021
  • 3 locations
None
To Evaluate the Safety and Pharmacokinetics of Parscaclisib in Participants With Normal Hepatic Function and Hepatic Impairment.

The purpose of the study is to evaluate the pharmacokinetics and safety of parsaclisib in participants With normal hepatic function and participants with hepatic impairment.

  • 0 views
  • 02 May, 2021
  • 4 locations
None
A Phase I Study of HRS2300 or Combined With SHR-1316 or SHR-1701 or Trametinib or Almonertinib in Patients With Advanced Malignancies

The study is being conducted to evaluate the safety and tolerability of HRS2300 and combined with SHR-1316 or SHR-1701 or trametinib or Almonertinib.To Determine the maximum tolerated dose (MTD) and recommended Dose (RP2D) for HRS2300 monotherapy and combination therapy.

  • 0 views
  • 10 Nov, 2021
  • 1 location